Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Naomi Motoji"'
Autor:
Hiroyuki Fukuda, Akiyo Shigematsu, Naomi Motoji, Mitsunobu Okuyama, Takaho Watayo, Masaaki Ebara, Hiromitsu Saisho, Masaharu Yoshikawa, Nobuyuki Sugiura, Ryo Shimizu
Publikováno v:
Carcinogenesis. 23:2019-2023
The aim of this study was to determine the metabolizing activities in the liver of patients with hepatocellular carcinoma (HCC). Thin-layer chromatography autoradioluminography was used to measure metabolizing activities. Succinate-producing activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a714c8cd4fa67d1ef45c7b1897942686
https://doi.org/10.1093/carcin/23.12.2019
https://doi.org/10.1093/carcin/23.12.2019
Publikováno v:
Experimental and Molecular Pathology. 69:119-143
In an attempt to improve liver slice culture for in vitro tests of newly developed drugs, we found that a relatively thick 2-mm slice was much more viable, long-lived, and metabolically functional than the conventionally used 300-μm-thick slices. Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a22691210f95ae7c4d411330c02f6b02
https://doi.org/10.1006/exmp.2000.2325
https://doi.org/10.1006/exmp.2000.2325
Autor:
Naomi Motoji, Yuko Hamai, Michiaki Aihara, Yasuhiko Hatori, Sadahiko Iwai, Kenji Miura, Akiyo Shigematsu, Masashi Ogawa, Masayasu Asaumi
Publikováno v:
Experimental and Molecular Pathology. 67:75-90
To assess recent improvements in quantitative whole-body autoradioluminography (QWBA), the entire QWBA procedure was divided into five processes. Each process was then investigated carefully to determine whether there were any problems in defining a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71125e7340f7472145bd39ef71b429e3
https://doi.org/10.1006/exmp.1999.2272
https://doi.org/10.1006/exmp.1999.2272
Autor:
Noriaki Tatsuta, Naomi Suzuki, Keizo Koya, Takae Mochizuki, Naomi Motoji, Masayuki Kawakami, Lan Bo Chen, Akiyo Shigematsu, Tadao Shishido, Hiroyuki Kuroiwa
Publikováno v:
Cancer Chemotherapy and Pharmacology. 43:295-301
MKT-077 (1-ethyl-2-[[3-ethyl-5-(3-methylbenzothiazolin-2-yliden)]-4- oxothiazolidin-2-ylidenemethyl] pyridinium chloride), a novel rhodacyanine dye in phase I/II clinical trials, may provide a new approach to cancer therapy based on the accumulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37c3bb8746ada93f3d77f655600bdf8c
https://doi.org/10.1007/s002800050898
https://doi.org/10.1007/s002800050898
Autor:
Yukio Kato, Yuki Izumi, Yuichi Sugiyama, Akiyo Shigematsu, Hiroshi Kiwada, Tatsuro Irimura, Kazuhiko Shirota, Naomi Motoji, Hideyoshi Harashima, Naomi Mizuno
Publikováno v:
Journal of Hepatology. 28:878-885
Background/Aims/Methods: The distribution characteristics of a human colon carcinoma cell line, KM12-HX cells, were examined. After intraportal vein (i.p.v.) or intravenous (i.v.) injection into rats, almost all the injected tumor cells are distribut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44ba6f00855ef76c551a060322fd441
https://doi.org/10.1016/s0168-8278(98)80239-0
https://doi.org/10.1016/s0168-8278(98)80239-0
Publikováno v:
Drug Metabolism and Pharmacokinetics. 11:331-346
The absorption, distribution, and excretion of radioactivity were investigated following a single oral administration of 14C-cabergoline to rats. The protein binding of the drug was also investigated in vivo and in vitro. 1. After oral administration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::711a7c3df403e6c8362b4b0234ada12e
https://doi.org/10.2133/dmpk.11.331
https://doi.org/10.2133/dmpk.11.331
Publikováno v:
Drug Metabolism and Pharmacokinetics. 11:347-357
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcb59e2b47020c94c2458746d48f7ed0
https://doi.org/10.2133/dmpk.11.347
https://doi.org/10.2133/dmpk.11.347
Publikováno v:
Biological and Pharmaceutical Bulletin. 18:89-93
The process of obtaining 3H-autoradiographic (ARG) images has been expected for a long time. A few X-ray films with no protection layer are commercially available, however, they do not give a reliable image which can be quantitated and can give good
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd2ff7af53451d677ee8b7134b014fa
https://doi.org/10.1248/bpb.18.89
https://doi.org/10.1248/bpb.18.89
Publikováno v:
Biological and Pharmaceutical Bulletin. 18:108-114
Phosphor Imaging plates (IPs) with high sensitivity to both low- and high-energy radiation have been on the market since 1988. The TLC-autoradioluminography (ARLG) method was developed utilizing such IPs. The conventional TLC method was suited for di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb0edb55306ec3ba5814082ab2b1353
https://doi.org/10.1248/bpb.18.108
https://doi.org/10.1248/bpb.18.108
Autor:
Kazuhiro KANEKO, Kyoichi TADANO, Kiyomi NAKAJIMA, Teruaki YUZURIHA, Naomi MOTOJI, Naoshi KAWAI, Shinichi HASEGAWA, Akiyo SHIGEMATSU
Publikováno v:
Drug Metabolism and Pharmacokinetics. 9:171-183
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26563d928cb32908c3804c008083a4fa
https://doi.org/10.2133/dmpk.9.171
https://doi.org/10.2133/dmpk.9.171