Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Naomi Moris"'
Autor:
Hyung Chul Lee, Nidia M. M. Oliveira, Cato Hastings, Peter Baillie-Benson, Adam A. Moverley, Hui-Chun Lu, Yi Zheng, Elise L. Wilby, Timothy T. Weil, Karen M. Page, Jianping Fu, Naomi Moris, Claudio D. Stern
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Many amniote vertebrate species including humans can form identical twins from a single embryo, but this only occurs rarely. It has been suggested that the primitive-streak-forming embryonic region emits signals that inhibit streak formation
Externí odkaz:
https://doaj.org/article/9c08b08f731a4b5bbf4643f49d1dc0e7
Publikováno v:
Developmental Biology. 488:35-46
Gastrulation is a fundamental and critical process of animal development whereby the mass of cells that results from the proliferation of the zygote transforms itself into a recognizable outline of an organism. The last few years have seen the emerge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1c64d0f1c1d74fd22bf1a3b80843f3
https://doi.org/10.1016/j.ydbio.2022.05.002
https://doi.org/10.1016/j.ydbio.2022.05.002
Autor:
Naomi, Moris, Marta, Shahbazi
Publikováno v:
Seminars in Cell & Developmental Biology. 131:1-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bfe7c18bb24b1524d5466c22bbe9d3a
https://doi.org/10.1016/j.semcdb.2022.06.012
https://doi.org/10.1016/j.semcdb.2022.06.012
Autor:
Yoshihiro Yamanaka, Kumiko Yoshioka-Kobayashi, Sofiane Hamidi, Sirajam Munira, Kazunori Sunadome, Yi Zhang, Yuzuru Kurokawa, Ai Mieda, Jamie L. Thompson, Janet Kerwin, Steven Lisgo, Takuya Yamamoto, Naomi Moris, Alfonso Martinez-Arias, Taro Tsujimura, Cantas Alev
The segmented body plan of vertebrates is established during somitogenesis, a well-studied process in model organisms, but remains largely elusive in humans due to ethical and technical limitations. Despite recent advances with pluripotent stem cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0182152730d919cb08c0787152d23dd0
https://doi.org/10.1101/2022.06.03.494621
https://doi.org/10.1101/2022.06.03.494621
Publikováno v:
Stem Cell Reports
In recent years, a diverse array of in vitro cell-derived models of mammalian development have been described that hold immense potential for exploring fundamental questions in developmental biology, particularly in the case of the human embryo where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9b23e6b3feee8dddd163196c2d6716
http://europepmc.org/articles/PMC8185435
http://europepmc.org/articles/PMC8185435
Autor:
Naomi Moris, Julia Schröder, Sabitri Ghimire, Alexander van Oudenaarden, Susanne C. van den Brink, Alfonso Martinez Arias, Tina Balayo, Kerim Anlas, Anna Alemany
Publikováno v:
Nature, 582(7812), 410-415. Nature Publishing Group
Nature
Nature
The body plan of the mammalian embryo is shaped through the process of gastrulation, an early developmental event that transforms an isotropic group of cells into an ensemble of tissues that is ordered with reference to three orthogonal axes1. Althou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e426d3042fc0f6f8722ca81b317059
https://doi.org/10.1038/s41586-020-2383-9
https://doi.org/10.1038/s41586-020-2383-9
Autor:
Christopher B. Cooke, Naomi Moris
Publikováno v:
Development (Cambridge, England). 148(23)
Primordial germ cells (PGCs) form early in embryo development and are crucial precursors to functioning gamete cells. Considerable research has focussed on identifying the transcriptional characteristics and signalling pathway requirements that confe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7749c92f8ea47af23f8454e3d8476a46
https://pubmed.ncbi.nlm.nih.gov/34854891
https://pubmed.ncbi.nlm.nih.gov/34854891
Autor:
Manuela Jaklin, Naomi Moris, Alfonso Martinez Arias, Veronika Mantziou, Stefan Kustermann, Peter Baillie-Benson
Pharmaceuticals that are intended for use in patients of childbearing potential need to be tested for teratogenicity before marketing. Several pharmaceutical companies use animal-free in vitro models which allow a more rapid selection of lead compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50ab59d11b10a3d93154364e5922b71e
https://doi.org/10.1101/2021.03.30.437698
https://doi.org/10.1101/2021.03.30.437698
Autor:
Stefan Kustermann, Manuela Jaklin, Peter Baillie-Benson, Veronika Mantziou, Alfonso Martinez Arias, Naomi Moris
Publikováno v:
Reproductive Toxicology (Elmsford, N.y.)
Highlights • Gastruloids are a new in vitro platform for teratogenicity testing. • Teratogens disrupt gastruloid gene expression and morphology with imaging readout. • Medium-throughput gastruloid cultures are quantifiable with statistical robu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9cf1b134dc9480f0b0e2fbc3a212015
http://hdl.handle.net/10230/52710
http://hdl.handle.net/10230/52710
Publikováno v:
Developmental biology. 474
Technical and ethical limitations create a challenge to study early human development, especially following the first 3 weeks of development after fertilization, when the fundamental aspects of the body plan are established through the process called
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c0e1d1adff3c9123546e78e81f77c55
https://pubmed.ncbi.nlm.nih.gov/33484705
https://pubmed.ncbi.nlm.nih.gov/33484705