Výsledky vyhledávání - "Naomi M. Scott"

Akademický článek

Transplacental Innate Immune Training via Maternal Microbial Exposure: Role of XBP1-ERN1 Axis in Dendritic Cell Precursor Programming

Autor: Kyle T. Mincham, Anya C. Jones, Marie Bodinier, Naomi M. Scott, Jean-Francois Lauzon-Joset, Philip A. Stumbles, Anthony Bosco, Patrick G. Holt, Deborah H. Strickland

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

We recently reported that offspring of mice treated during pregnancy with the microbial-derived immunomodulator OM-85 manifest striking resistance to allergic airways inflammation, and localized the potential treatment target to fetal conventional de

Externí odkaz: https://doaj.org/article/3423c042a44e49cba6ba800a4faaeb34

Zobrazit plný text záznamu

Protection against neonatal respiratory viral infection via maternal treatment during pregnancy with the benign immune training agent OM-85

Autor: Deborah H. Strickland, Philip A. Stumbles, Jean Francois Lauzon-Joset, Patrick G. Holt, Kyle T Mincham, Yasmine Khandan, Naomi M. Scott

Publikováno v: Clinical & Translational Immunology
Clinical & Translational Immunology, Vol 10, Iss 7, Pp n/a-n/a (2021)

Objectives Incomplete maturation of immune regulatory functions at birth is antecedent to the heightened risk for severe respiratory infections during infancy. Our forerunner animal model studies demonstrated that maternal treatment with the microbia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91f762dc168cac6e9ca46f4a335666f
https://pubmed.ncbi.nlm.nih.gov/34249358

Zobrazit plný text záznamu

Protection against neonatal respiratory viral infection via maternal treatment during pregnancy with the benign immune training agent OM-85

Autor: Patrick G. Holt, Deborah H. Strickland, Yasmine Khandan, Jean Francois Lauzon-Joset, Naomi M. Scott, Kyle T Mincham, Philip A. Stumbles

ObjectivesIncomplete maturation of immune regulatory functions at birth are antecedent to the heightened risk for severe respiratory infections during infancy. Our forerunner animal model studies demonstrated that maternal treatment with the benign m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::088e1d3e747b905326f832b42073bd0c
https://doi.org/10.1101/2021.03.02.433517

Zobrazit plný text záznamu

Transplacental Innate Immune Training via Maternal Microbial Exposure: Role of XBP1-ERN1 Axis in Dendritic Cell Precursor Programming

Autor: Jean Francois Lauzon-Joset, Naomi M. Scott, Anya C. Jones, Marie Bodinier, Kyle T Mincham, Deborah H. Strickland, Patrick G. Holt, Philip A. Stumbles, Anthony Bosco

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2020, 11, pp.601494. ⟨10.3389/fimmu.2020.601494⟩
Frontiers in Immunology, Vol 11 (2020)

International audience; We recently reported that offspring of mice treated during pregnancy with the microbial-derived immunomodulator OM-85 manifest striking resistance to allergic airways inflammation, and localized the potential treatment target

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a00ed74816f2205bcb083fd0a1efc3e
https://doi.org/10.3389/fimmu.2020.601494

Zobrazit plný text záznamu

Nasal Delivery of a Commensal Pasteurellaceae Species Inhibits Nontypeable Haemophilus influenzae Colonization and Delays Onset of Otitis Media in Mice

Autor: Sharon L. Clark, Peter Richmond, Camilla de Gier, Katrien M. J. Sutherland, Lea-Ann S. Kirkham, Janessa Pickering, Ruth B. Thornton, Caitlyn Granland, Naomi M. Scott, Jean-Francois Lauzon-Joset, Jeroen D. Langereis, Deborah H. Strickland

Publikováno v: Infection and Immunity, 88
Infection and Immunity
Infection and Immunity, 88, 4

Nasopharyngeal colonization with nontypeable Haemophilus influenzae (NTHi) is a prerequisite for developing NTHi-associated infections, including otitis media. Therapies that block NTHi colonization may prevent disease development. We previously demo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97886c4543f1032da2c590c64ca64463
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/218895

Zobrazit plný text záznamu

PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo

Autor: Philip Newsholme, Leonard I. Zon, Terence McGonigle, Amy R. Dwyer, Prue H. Hart, Naomi M. Scott, Helen S. Goodridge, Kevin N. Keane, Fiona J. Pixley, Eloise L Greenland

Publikováno v: Experimental Hematology. 56:64-68

Monocytes/macrophages differentiating from bone marrow (BM) cells pulsed for 2 hours at 37°C with a stabilized derivative of prostaglandin E2, 16,16-dimethyl PGE2 (dmPGE2), migrated less efficiently toward a chemoattractant than monocytes/macrophage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e01faa4acd81d8b941a9988d484513b1
https://doi.org/10.1016/j.exphem.2017.08.002

Zobrazit plný text záznamu

UV Irradiation of Skin Enhances Glycolytic Flux and Reduces Migration Capabilities in Bone Marrow–Differentiated Dendritic Cells

Autor: Kim W. Carter, Fiona J. Pixley, Amy R. Dwyer, Prue H. Hart, Helen S. Goodridge, Naomi M. Scott, Philip Newsholme, Kevin N. Keane, Simon Ghaly, Terence McGonigle, Eloise L Greenland, Denise Anderson

Publikováno v: The American Journal of Pathology. 187:2046-2059

A systemic immunosuppression follows UV irradiation of the skin of humans and mice. In this study, dendritic cells (DCs) differentiating from the bone marrow (BM) of UV-irradiated mice had a reduced ability to migrate toward the chemokine (C-C motif)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140b54d13d3cf40eb982ecf3b7fe60c7
https://doi.org/10.1016/j.ajpath.2017.06.003

Zobrazit plný text záznamu

Transplacental innate immune training via maternal microbial exposure: the XBP1-ERN1 axis in programming dendritic cell precursors

Autor: Marie Bodinier, Patrick G. Holt, Anthony Bosco, Jean-Francois Lauzon-Joset, Deborah H. Strickland, Anya C Jones, Kyle T Mincham, Naomi M. Scott, Philip A. Stumbles

We recently reported that the offspring of mice treated during pregnancy with the microbial-derived immunomodulator OM-85 manifest striking resistance postnatally to allergic airways inflammation, and localised the potential treatment target to the f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::238ca17680f37d687ae8f26750b3caec
https://doi.org/10.1101/848242

Zobrazit plný text záznamu

Early life ovalbumin sensitization and aerosol challenge for the induction ofallergic airway inflammation in a BALB/c murine model

Autor: Deborah H. Strickland, Patrick G. Holt, Jonatan Leffler, Kyle T Mincham, Philip A. Stumbles, Jean-Francois Lauzon-Joset, Naomi M. Scott

Publikováno v: Bio Protoc

The early life period represents a time of immunological plasticity whereby the functionally immature immune system is highly susceptible to environmental stimulation. Perennial aeroallergen and respiratory viral infection induced sporadic episodes o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc143072982b957bce90a8e18579e22
https://europepmc.org/articles/PMC7854073/

Zobrazit plný text záznamu

Quantification of serum ovalbumin-specific immunoglobulin E titrevia

Autor: Kyle T Mincham, Patrick G. Holt, Jean-Francois Lauzon-Joset, Naomi M. Scott, Philip A. Stumbles, Deborah H. Strickland, Jonatan Leffler

Publikováno v: Bio Protoc

Murine models of allergic airway disease are frequently used as a tool to elucidate the cellular and molecular mechanisms of tissue-specific asthmatic disease pathogenesis. Paramount to the success of these models is the induction of experimental ant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8549f8f92ca25b9dd4680915d44af5
https://pubmed.ncbi.nlm.nih.gov/33654986

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání