Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Naomi M. Fast"'
Autor:
Vojtečh Žárský, Anna Karnkowska, Vittorio Boscaro, Morelia Trznadel, Thomas A. Whelan, Markus Hiltunen-Thorén, Ioana Onut-Brännström, Cathryn L. Abbott, Naomi M. Fast, Fabien Burki, Patrick J. Keeling
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background Intracellular symbionts often undergo genome reduction, losing both coding and non-coding DNA in a process that ultimately produces small, gene-dense genomes with few genes. Among eukaryotes, an extreme example is found in microsp
Externí odkaz:
https://doaj.org/article/14aeb87960734657a8ad4087ac77e9f7
Autor:
Corbin S. Black, Thomas A. Whelan, Erin L. Garside, Andrew M. MacMillan, Naomi M. Fast, Stephen D. Rader
Publikováno v:
RNA. 29:531-550
Premessenger RNA splicing is catalyzed by the spliceosome, a multimegadalton RNA–protein complex that assembles in a highly regulated process on each intronic substrate. Most studies of splicing and spliceosomes have been carried out in human orS.
Publikováno v:
The Journal of eukaryotic microbiologyREFERENCES.
The Cyanidiales are a group of mostly thermophilic and acidophilic red algae that thrive near volcanic vents. Despite their phylogenetic relationship, the reduced genomes of Cyanidioschyzon merolae and Galdieria sulphuraria are strikingly different w
Autor:
Peter Sarkies, Murray E Selkirk, John T Jones, Vivian Blok, Thomas Boothby, Bob Goldstein, Ben Hanelt, Alex Ardila-Garcia, Naomi M Fast, Phillip M Schiffer, Christopher Kraus, Mark J Taylor, Georgios Koutsovoulos, Mark L Blaxter, Eric A Miska
Publikováno v:
PLoS Biology, Vol 13, Iss 2, p e1002061 (2015)
Small RNA pathways act at the front line of defence against transposable elements across the Eukaryota. In animals, Piwi interacting small RNAs (piRNAs) are a crucial arm of this defence. However, the evolutionary relationships among piRNAs and other
Externí odkaz:
https://doaj.org/article/601dc193696d4431b695f3cd4f773700
Autor:
Naomi M. Fast
Publikováno v:
Current biology : CB. 31(14)
Summary Whereas most eukaryotic genes are interrupted by introns removed by the U2 (major) spliceosome, U12-type introns are extremely rare. New work uncovers a case of extensive U12-type intron gain, and an unexpectedly flexible and efficient U12 (m
Publikováno v:
Genome Biology and Evolution
Spliceosomal introns are ubiquitous features of eukaryotic genomes, but the mechanisms responsible for their loss and gain are difficult to identify. Microsporidia are obligate intracellular parasites that have significantly reduced genomes and, as a
Publikováno v:
Journal of Eukaryotic Microbiology. 68
Pre-mRNA splicing is a highly conserved eukaryotic process, but our understanding of it is limited by a historical focus on well-studied organisms such as humans and yeast. There is considerable diversity in mechanisms and components of pre-mRNA spli
Autor:
Niels Van Steenkiste, Jingwen Pan, Denis V. Tikhonenkov, Vittorio Boscaro, Jürgen F. H. Strassert, Filip Husnik, Thomas A. Whelan, Emma E. George, Floyd T. Bardell, Noriko Okamoto, Brian S. Leander, Vera Tai, Greg S. Gavelis, Nicholas A.T. Irwin, Fabien Burki, Ryan M.R. Gawryluk, Martin Kolisko, Matthew Whalen, Elisabeth Hehenberger, Cameron J. Grisdale, Jan Janouškovec, Elizabeth C. Cooney, Anna Cho, Mitchell J. Syberg-Olsen, David Roy Smith, Behzad Imanian, Jean-François Pombert, Varsha Mathur, Patrick J. Keeling, Rebecca Fiorito, Javier del Campo, India Stephenson, Alexandros A. Pittis, Juan F. Saldarriaga, Laura Wegener Parfrey, Anna Karnkowska, Racquel A. Singh, Rhea D. Sanders, María Herranz, Thierry J. Heger, Rachael N. Gomm-Kolisko, Erick R. James, Naomi M. Fast, Ferdous Nawar, Donald Wong, Waldan K. Kwong, Yoshihisa Hirakawa, Mona Sabetrasekh
Publikováno v:
Aquatic Ecosystem Health & Management. 23:17-18
Denis,It’s ironic that when facing a problem like this – being asked to write a piece about the way you affected us in the labs we share – our first instinct would be to come and talk to you, to ge...
Autor:
Naomi M. Fast, Andrew M. MacMillan, Martha R. Stark, T.A. Whelan, Erin L. Garside, Stephen D. Rader
Publikováno v:
Journal of molecular biology. 431(14)
Conformational rearrangements are critical to regulating the assembly and activity of the spliceosome. The spliceosomal protein Prp8 undergoes multiple conformational changes during the course of spliceosome assembly, activation, and catalytic activi
Publikováno v:
Genome Biology and Evolution
Eukaryotic genes are interrupted by introns that are removed in a conserved process known as pre-mRNA splicing. Though well-studied in select model organisms, we are only beginning to understand the variation and diversity of this process across the