Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Naomi M Walsh"'
Autor:
Naomi M Walsh, Michael R Botts, Andrew J McDermott, Sébastien C Ortiz, Marcel Wüthrich, Bruce Klein, Christina M Hull
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007777 (2019)
The majority of invasive human fungal pathogens gain access to their human hosts via the inhalation of spores from the environment into the lung, but relatively little is known about this infectious process. Among human fungal pathogens the most freq
Externí odkaz:
https://doaj.org/article/96e7a6ae9231499f8b7c44a9e0c8c633
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173866 (2017)
Phagocytosis by innate immune cells is an important process for protection against multiple pathologies and is particularly important for resistance to infection. However, phagocytosis has also been implicated in the progression of some diseases, inc
Externí odkaz:
https://doaj.org/article/6de3d77159274ec0938275d7f2012e1e
Autor:
Marcel Wüthrich, Michael R. Botts, Christina M. Hull, Sébastien C. Ortiz, Bruce S. Klein, Andrew J. McDermott, Naomi M. Walsh
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007777 (2019)
PLoS Pathogens
PLoS Pathogens
The majority of invasive human fungal pathogens gain access to their human hosts via the inhalation of spores from the environment into the lung, but relatively little is known about this infectious process. Among human fungal pathogens the most freq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3896af3fd9478783b3c515d4fccc838b
https://doaj.org/article/96e7a6ae9231499f8b7c44a9e0c8c633
https://doaj.org/article/96e7a6ae9231499f8b7c44a9e0c8c633
Autor:
Christina M. Hull, Leslie A. Rank, Fang Yun Lim, Samuel H. Gellman, Nancy P. Keller, Naomi M. Walsh
Publikováno v:
mSphere
mSphere, Vol 3, Iss 3, p e00223-18 (2018)
mSphere, Vol 3, Iss 3 (2018)
mSphere, Vol 3, Iss 3, p e00223-18 (2018)
mSphere, Vol 3, Iss 3 (2018)
Fungi reside in all ecosystems on earth and impart both positive and negative effects on human, plant, and animal health. Fungal disease is on the rise worldwide, and there is a critical need for more effective and less toxic antifungal agents. Nylon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b6e737f31c454ca8b73c7ec1969b0f
http://europepmc.org/articles/PMC5967195
http://europepmc.org/articles/PMC5967195
Autor:
Nancy P. Keller, Naomi M. Walsh, Mingwei Huang, Fang Yun Lim, Runhui Liu, Samuel H. Gellman, Jin Woo Bok, Christina M. Hull, Leslie A. Rank
Publikováno v:
Antimicrobial Agents and Chemotherapy. 61
Invasive fungal diseases are generally difficult to treat and often fatal. The therapeutic agents available to treat fungi are limited, and there is a critical need for new agents to combat these deadly infections. Antifungal compound development has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ffdff7772488a970bf8e465c0904c5d
https://doi.org/10.1128/aac.00204-17
https://doi.org/10.1128/aac.00204-17
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 3, p e0173866 (2017)
PLoS ONE, Vol 12, Iss 3, p e0173866 (2017)
Phagocytosis by innate immune cells is an important process for protection against multiple pathologies and is particularly important for resistance to infection. However, phagocytosis has also been implicated in the progression of some diseases, inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28cbc7b8a1bf6e2b6252775c7c8b5a01
http://europepmc.org/articles/PMC5345868
http://europepmc.org/articles/PMC5345868
Publikováno v:
Integrative biology : quantitative biosciences from nano to macro. 8(5)
Germination of spores into actively growing cells is a process essential for survival and pathogenesis of many microbes. Molecular mechanisms governing germination, however, are poorly understood in part because few tools exist for evaluating and int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7dc6790b3cd4e9fd589eb490a88031a
https://pubmed.ncbi.nlm.nih.gov/27026574
https://pubmed.ncbi.nlm.nih.gov/27026574
Publikováno v:
Proceedings of the National Academy of Sciences. 108:9101-9106
Phospholamban (PLN) is a type II membrane protein that inhibits the sarcoplasmic reticulum Ca 2+ -ATPase (SERCA), thereby regulating calcium homeostasis in cardiac muscle. In membranes, PLN forms pentamers that have been proposed to function either a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d501ce27efffe4869174c85ef85b652
https://doi.org/10.1073/pnas.1016535108
https://doi.org/10.1073/pnas.1016535108
Autor:
Gianluigi Veglia, Raffaello Verardi, Neha Abrol, Kailey J. Soller, Naomi M. Walsh, Michael T. Bowser, Seth L. Robia, Meng Jing, Jing Yang, Vitaly V. Vostrikov
Publikováno v:
Scientific Reports
The membrane protein complex between sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) and phospholamban (PLN) is a prime therapeutic target for reversing cardiac contractile dysfunctions caused by calcium mishandling. So far, however, efforts to deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::251ad3a3351d7e75558c200a6da3c583
https://doi.org/10.1038/srep13000
https://doi.org/10.1038/srep13000
Autor:
Leslie A. Rank, Naomi M. Walsh, Fang Yun Lim, Samuel H. Gellman, Nancy P. Keller, Christina M. Hull
Publikováno v:
mSphere, Vol 3, Iss 3 (2018)
ABSTRACT Understanding the dimensions of fungal diversity has major implications for the control of diseases in humans, plants, and animals and in the overall health of ecosystems on the planet. One ancient evolutionary strategy organisms use to mana
Externí odkaz:
https://doaj.org/article/7868c5f32cd746d6b36bc6d4367326c2