Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Naomi Kraus-Friedmann"'
Autor:
Naomi Kraus-Friedmann
Publikováno v:
Metabolism. 51:79-91
Previous data from our laboratory indicated a role for the cytoskeleton in the hormonal stimulation of gluconeogenesis. To gain further insight into the role of the cytoskeleton in the regulation of gluconeogenesis, we performed further experiments t
Autor:
Naomi Kraus-Friedmann
Publikováno v:
Cell Calcium. 27:127-138
Cyclic nucleotide-gated channels represent a class of ion channels activated directly by the binding of either cyclic-GMP or cyclic-AMP. They carry both mono and divalent cations, but select calcium over sodium. In the majority of the cases studied,
Publikováno v:
Metabolism. 48:1241-1247
Previous studies have suggested a role for the actin cytoskeleton in hormonally evoked Ca2+ signaling in the liver. Here, we present evidence supporting a connection between filamentous actin (F-actin) organization and the ability of vasopressin and
Autor:
Li Feng, Naomi Kraus-Friedmann
Publikováno v:
Biochemical Pharmacology. 48:2157-2162
The mechanism of action of the immunosuppressant FK506 in the liver was studied. The hypothesis was tested that FK506 exerts its effect in the liver by interacting with the ryanodine-binding Ca2+ release channel. Two types of experiments were carried
Autor:
Li Feng, Naomi Kraus-Friedmann
Publikováno v:
Biochemical and Biophysical Research Communications. 205:291-297
Hepatic parenchymal cells possess two receptors for 1,4,5-trisphosphate, one isolated with the plasma membrane fraction and another isolated with the nuclear fraction. Their interaction with antibodies generated against the receptor in the cerebellum
Autor:
Naomi Kraus-Friedmann
Publikováno v:
Cell Motility and the Cytoskeleton. 28:279-284
Publikováno v:
The Journal of Biochemistry. 107:550-553
The mechanism by which GTP induces Ca2+ release from Ca2(+)-preloaded rat hepatic microsomes was studied. In the same concentration range as that for Ca2+ release, GTP inhibited the initial rate of ATP-driven Ca2+ uptake. It also inhibited the format
Autor:
Naomi Kraus-Friedmann, Li Feng
Publikováno v:
Metabolism: clinical and experimental. 45(3)
A hypothesis for the hormonal regulation of gluconeogenesis, in which increases in cytosolic free-Ca2+ levels ([Ca2+]i) play a major role, is presented. This hypothesis is based on the observation that gluconeogenic hormones evoke a common pattern of
Autor:
Liliana Hernandez, Roberto Barbosa Bazotte, Naomi Kraus-Friedmann, Salvador Uribe, Bethany Pereira, Li Feng
Publikováno v:
Biochemical pharmacology. 44(3)
The effects of ryanodine, a plant alkaloid which alters Ca 2+ sequestration in the liver, on O 2 uptake and gluconeogenesis were measured. Ryanodine administration to perfused rat liver resulted in the stimulation of O 2 uptake and of gluconeogenesis
Autor:
Naomi Kraus-Friedmann, Varda Shoshan-Barmatzt, Sandra C. Higham, Bethany Pereira, Roberto Barbosa Bazotte
Publikováno v:
Biochemical pharmacology. 42(9)
Ryanodine, a highly toxic alkaloid known to react specifically with the Ca2+ release channels in sarcoplasmic reticulum (SR), was employed to study Ca2+ sequestration in the liver. Ryanodine at a 200 microM concentration increased cytosolic free Ca2+