Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Naomi Kanai"'
Autor:
Nobukazu Tsukamoto, Akihiro Yamamura, Fuyuhiko Motoi, Takuya Moriya, Keiko Abe, Hiroki Hayashi, Masanori Akada, Makoto Sunamura, Naoyuki Kaneko, Kentaro Shima, Michiaki Unno, Yuriko Saiki, Satoru Yokoyama, Hisashi Abe, Shinichi Egawa, Kazuyuki Ishida, Akira Horii, Zhaodi Gu, Emiko Kondo, Naomi Kanai, Takahiro Tabata
Publikováno v:
Pancreas. 42:1027-1033
Objectives Pancreatic cancer is one of the most lethal malignancies; its poor prognosis is strongly associated with invasion and metastasis. Expression of S100A4 has been reported to correlate with poor prognosis in various cancers. We have investiga
Publikováno v:
Journal of Human Genetics. 50:159-167
Our previous study indicated that DUSP6/MKP-3/PYST1 could act as a tumor suppressor in human pancreatic cancer. DUSP6 was frequently underexpressed in primary pancreatic cancer tissues by an unknown mechanism. In this study, we demonstrated that hype
Publikováno v:
Oncogene. 25(35)
DUSP6/MKP-3, a specific inhibitor of MAPK1/ERK2, frequently loses its expression in primary pancreatic cancer tissues. This evidence suggests that constitutive activation of MAPK1 synergistically induced by frequent mutation of KRAS2 and the loss of
Autor:
Toru Furukawa, Akira Horii, Kazunori Takeda, Tadayoshi Abe, Yoshitaro Yoshida, Rumi Fujisaki, Makoto Sunamura, Seiki Matsuno, Naomi Kanai
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 18(8)
DUSP6/MKP-3 is identified as a candidate tumor suppressor gene for pancreatic cancer. The aim of this study was to elucidate the roles of DUSP6 in the pancreatic carcinogenesis through the pancreatic intraepithelial neoplasia and/or intraductal papil
Publikováno v:
International Journal of Cardiology. 150:227-228