Výsledky vyhledávání - "Naomi I. Nakano"

Correlation between salivary and plasma levels of acetaminophen

Autor: Naomi I. Nakano, Kaoru Iwasaka, Masahiro Nakano, Shoko Funada

Publikováno v: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 19:549-553

A single oral dose of 500 mg of acetaminophen was administered to each of six female volunteers. Twenty-four paired plasma and saliva samples were obtained and the saliva to-plasma concentration ratio (S/P) was determined to be 0. 95 with a correlati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cdb0331467af93a204c18d4bbef63ad5
https://doi.org/10.3999/jscpt.19.549

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Preparation and drug adsorption characteristics of activated carbon beads suitable for oral administration

Autor: Naomi I. Nakano, Yoshimitsu Shimamori, Misako Umehashi, Masahiro Nakano

Publikováno v: Chemical and Pharmaceutical Bulletin. 32:699-707

An activated carbon preparation suitable for oral administration as an intestinal adsorbent was prepared by drying spherical beads of 48 to 250 mesh in which 8% activated carbon powder was dispersed. The final preparation, dried activated carbon bead

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e501ae1739573dc3ccb50a0406f0189b
https://doi.org/10.1248/cpb.32.699

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Quantitative Study of Drug-Protein Interactions by High Performance Liquid Chromatography : Use of Albumin Immobilized Porous Glass Beads

Autor: Naomi I. Nakano, Yoshimitsu Shimamori

Publikováno v: YAKUGAKU ZASSHI. 103:771-775

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1fa9350ac73c3fd118c3a31fad015069
https://doi.org/10.1248/yakushi1947.103.7_771

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Binding capacities of human serum albumin monomer and dimer by continuous frontal affinity chromatography

Autor: Naomi I. Nakano, Yoshimitsu Shimamori, Shigenori Yamaguchi

Publikováno v: Journal of Chromatography A. 237:225-232

Human serum albumin monomer and dimer obtained by fractionation of a commercial preparation were immobilized on CH-Sepharose 4B by covalent coupling. For salicylic acid, warfarin, phenylbutazone, mefenamic acid, sulphamethizole and sulphonylureas, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a614af35332411bc0c45b26d285298
https://doi.org/10.1016/s0021-9673(00)83229-x

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[Untitled]

Autor: Reiko Iwaoku, Naomi I. Nakano, Yoshiteru Honda, Masahiro Nakano

Publikováno v: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 15:437-443

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::25f2002aef6591522d09648e551f36fd
https://doi.org/10.3999/jscpt.15.437

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Study of Drug-Protein Binding by Affinity Chromatography: Interaction of Bovine Serum Albumin and Salicylic Acid

Autor: Takashi Amiya, Naomi I. Nakano, Yukio Fujimqto, Takayuki Oshio

Publikováno v: Journal of Pharmaceutical Sciences. 67:1005-1008

The affinity chromatographic technique was used to study the interaction of bovine serum albumin and salicylic acid at 3.3 +/- 1.1 degrees. Beaded agarose gel, on which the albumin was immobilized by covalent linkage, was packed in a column as an aff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4e8dfaf9f907c4730906d84f3298f3
https://doi.org/10.1002/jps.2600670737

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Mutual displacement interactions in the binding of two drugs to human serum albumin by frontal affinity chromatography

Autor: Naomi I. Nakano, Shigenori Yamaguchi, Yoshimitsu Shimamori

Publikováno v: Journal of Chromatography A. 188:347-356

A continuous frontal analysis chromatographic method was developed for studying the simultaneous binding of two drugs or ligands with an immobilized macromolecule. The usefulness of this method was demonstrated in the interactions of sulphamethizole

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee76bd2cd540a9a217ce023b6d93090a
https://doi.org/10.1016/s0021-9673(00)81257-1

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Nucleophilic and bifunctional catalysis. Mechanism, reactivity, and transition-state structure in the hydrolysis of 2-chloro-4-isopropylamino-6-cyclopropylamino-s-triazine by N-hydroxysuccinimide and 1-hydroxy-2-piperidone

Autor: Naomi I. Nakano, Richard L. Schowen, Edward E. Smissman

Publikováno v: The Journal of Organic Chemistry. 38:4396-4401

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d2eb8eb6f140868a452db1cb2f82657
https://doi.org/10.1021/jo00965a010

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In vitro adsorption characteristics of bile salt anions by activated carbon beads for oral administration

Autor: Naomi I. Nakano, Masahiro Nakano, Shoko Funada, Yoshiteru Honda

Publikováno v: Chemical and Pharmaceutical Bulletin. 32:4096-4102

Adsorption characteristics of bile salt anions by activated carbon beads consisting of about 67% activated carbon powder in agar were studies in vitro and compared with those of a cholestyramine preparation from the standpoint of usefulness for seque

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86eece98f8ce1b99dbfda79789ff1977
https://doi.org/10.1248/cpb.32.4096

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