Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Naomi Hachiya"'
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250277 (2021)
Post-translational modifications are often detected in age-related diseases associated with protein misfolding such as cataracts from aged lenses. One of the major post-translational modifications is the isomerization of aspartate residues (L-isoAsp)
Externí odkaz:
https://doaj.org/article/ef9bf45bcce54e939e6486f208909283
Autor:
Yuki Kawaguchi, Masato Taoka, Takahiro Takekiyo, Takamasa Uekita, Ikuo Shoji, Naomi Hachiya, Tohru Ichimura
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169436 (2017)
The spontaneous and energy-releasing reaction of protein aggregation is typically prevented by cellular quality control machinery (QC). TRIM32 is a member of the TRIM (tripartite motif-containing) ubiquitin E3 ligases, and when overexpressed in cultu
Externí odkaz:
https://doaj.org/article/b283b85d83ab415ea79ba3ed71c9711a
Autor:
Hiroki Miyahara, Jian Dai, Ying Li, Xiaoran Cui, Hibiki Takeuchi, Naomi Hachiya, Fuyuki Kametani, Masahide Yazaki, Masayuki Mori, Keiichi Higuchi
Publikováno v:
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.
Amyloidosis refers to a group of degenerative diseases that are characterized by the deposition of misfolded protein fibrils in various organs. Deposited amyloid may be removed by a phagocyte-dependent innate immune system; however, the precise mecha
Autor:
Naomi, Hachiya
Publikováno v:
東京医科大学雑誌. 72(1):12-18
Autor:
Katsuyoshi Mihara, Kitaru Suda, Gottfried Schatz, Martin Horst, Trevor Lithgow, Naomi Hachiya
Publikováno v:
Nature. 376:705-709
We have reconstituted the initial steps of mitochondrial protein import with a purified precursor protein, a purified, ATP-dependent, cytosolic chaperone selective for mitochondrial precursors (mitochondrial import stimulating factor; MSF), and eithe
Autor:
Naomi, Hachiya, Kiyotoshi, Kaneko
Publikováno v:
Nihon rinsho. Japanese journal of clinical medicine. 69
Autor:
Naomi, Hachiya, Kiyotoshi, Kaneko
Publikováno v:
Nihon rinsho. Japanese journal of clinical medicine. 69
Autor:
Kiyotoshi, Kaneko, Naomi, Hachiya
Publikováno v:
Nihon rinsho. Japanese journal of clinical medicine. 69
Publikováno v:
Journal of Biological Chemistry. 269:30893-30897
MSF, a mitochondrial import stimulation factor purified from rat liver cytosol, is an ATP-dependent precursor protein conformational modulator. As a step toward understanding the specificity of substrate recognition by MSF, various synthetic peptides
Autor:
Katsuyoshi Mihara, Tsuneo Omura, Rashidul Alam, Shun Ichiro Kawabata, Masao Sakaguchi, Masato Kitajima, Naomi Hachiya, Sadaaki Iwanaga
Publikováno v:
The Journal of Biochemistry. 116:416-425
We identified a liver cytosolic protein factor that stimulated the import of wheat germ lysate-synthesized precursor proteins into mitochondria. It was termed mitochondrial import stimulation factor or MSF [Hachiya, N. et al. (1993) EMBO J. 12, 1579-