Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Naomi Friedmann"'
Autor:
Naomi Friedmann, George E. Dambach
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 596:180-185
In the perfused rat liver, administration of glucagon causes a hyperpolarization of the liver cell membrane and increases gluconeogenesis. Insulin, a hormone which is known to antagonize the effect of glucagon on gluconeogenesis also blocks the hyper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b86a1bd8b9593ae8898d57c6914cd955
https://doi.org/10.1016/0005-2736(80)90352-1
https://doi.org/10.1016/0005-2736(80)90352-1
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 630:165-175
The characteristics and kinetics of calcium uptake activity were studied in isolated hepatic microsomes. The sustained accumulation of calcium was ATP- and oxalate-dependent. Glucagon increased microsomal Ca2+ uptake upon either in vivo injection, or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4003d0f347fa2a805dde11f23a658e3e
https://doi.org/10.1016/0304-4165(80)90418-3
https://doi.org/10.1016/0304-4165(80)90418-3
Autor:
Naomi Friedmann
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 428:495-508
Although it is known that protein kinases are activated by cyclic AMP, the role of the activated kinase in the gluconeogenic response to cyclic AMP is not known. Therefore, we examined whether the inhibition of the gluconeogenic response in the liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c9dc38c247bbf843fdf9468679c48ea
https://doi.org/10.1016/0304-4165(76)90058-1
https://doi.org/10.1016/0304-4165(76)90058-1
Autor:
George Dambach, Naomi Friedmann
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 332:374-386
In the rat liver perfused in situ with Krebs-Ringer bicarbonate buffer, glucagon or cyclic AMP administration is followed by increased glucose production, hyper-polarization of the liver cells and a large efflux of intracellular Na. Total substitutio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4172df5d3986cfd1477e40dbd31cab6c
https://doi.org/10.1016/0005-2736(74)90360-5
https://doi.org/10.1016/0005-2736(74)90360-5
Publikováno v:
Biochemical and Biophysical Research Communications. 82:603-608
The effects of glucagon and insulin on hepatic microsomal calcium uptake were investigated. Microsomes isolated from perfused rat liver accumulated calcium in the presence of ATP and oxalate. Addition of glucagon to the perfusate significantly increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec730a9d1543bd2a2819c99ca0a8083
https://doi.org/10.1016/0006-291x(78)90917-8
https://doi.org/10.1016/0006-291x(78)90917-8
Autor:
Ellen Hee-Aik Wong, John H. Exton, Jackie D. Corbin, Naomi Friedmann, Charles R. Park, J. Parke Brineaux
Publikováno v:
Journal of Biological Chemistry. 247:3579-3588
The effects of glucagon and epinephrine on gluconeogenesis and glycogenolysis in liver and of catecholamines and adrenocorticotrophic hormone on lipolysis in adipose tissue were examined in normal and adrenalectomized rats. Glucagon or epinephrine st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3594b8b0f54e7c6a34afd44c8bc9fbe
https://doi.org/10.1016/s0021-9258(19)45180-6
https://doi.org/10.1016/s0021-9258(19)45180-6
Autor:
Naomi Friedmann, Howard Rasmussen
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 222:41-52
In the isolated perfused rat liver, administration of either glucagon or 3′,5′-AMP is followed by an efflux of Ca 2+ and enhanced glucose formation from lactate or pyruvate. The release of Ca 2+ precedes the increase in glucose production. The Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbbbac2d0014e08034726321f7586710
https://doi.org/10.1016/0304-4165(70)90349-1
https://doi.org/10.1016/0304-4165(70)90349-1
Autor:
H.E. Wertheimer, Naomi Friedmann
Publikováno v:
Metabolism. 15:222-229
2-Deoxyglucose (2DG) an inhibitor of glucose metabolism,1 induced hyperglycemia and increased endogenic gluconeogenesis. These effects are seen 5–10 minutes after the administration of 2DG. Two hours later an increased liver glycogen content was fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed189b7154e75297b9a600c2098c4a55
https://doi.org/10.1016/0026-0495(66)90019-9
https://doi.org/10.1016/0026-0495(66)90019-9
Publikováno v:
Annals of the New York Academy of Sciences. 185:108-114
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc78295c275b003a0403285a9fd8e36
https://doi.org/10.1111/j.1749-6632.1971.tb45241.x
https://doi.org/10.1111/j.1749-6632.1971.tb45241.x
Publikováno v:
Science. 171:400-402
Cyclic adenosine monophosphate, cyclic guanosine monophosphate, glucagon, and isoproterenol each hyperpolarized perfused rat liver cells. The hyperpolarization followed a time course similar to the stimulated increase in potassium efflux and was prec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b01ea556ae8bf15c664e05b2e9b540
https://doi.org/10.1126/science.171.3969.400
https://doi.org/10.1126/science.171.3969.400