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Autor:
Guy Rosner, Naomi Fliss-Issakov, Shai Carmi, Nathan Gluck, Oren Shibolet, Sivan Aharon-Caspi, Dani Bercovich, Revital Kariv, Merav Ben-Yehoyada, Efrat Kellerman, Hana Strul
Publikováno v:
Diseases of the colon and rectum. 61(9)
Germline mutations in the DNA polymerase genes POLD1 and POLE confer high risk for multiple colorectal adenomas and colorectal cancer. However, prevalence and the clinical phenotype of mutation carriers are still not fully characterized.The purpose o