Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Naomi Feinstein"'
Publikováno v:
Journal of Structural Biology. 177:106-112
The nuclear lamina is a major structural element of the nucleus and is predominately composed of the intermediate filament lamin proteins. Missense mutations in the human lamins A/C cause a family of laminopathic diseases, with no known mechanistic l
Autor:
Eitan Erez Zahavi, Mor Nitzan, Michael S. Donnenberg, Joshua A. Lieberman, Naomi Feinstein, Kobi Baruch, Ilan Rosenshine, Benjamin Aroeti, Jerrold R. Turner, Naomi Melamed-Book, Efrat Zlotkin-Rivkin
Publikováno v:
Molecular Biology of the Cell
Enteropathogenic Escherichia coli (EPEC) and other pathogenic bacteria use dynamic type IV pili to adhere to the host. Here we show that the capacity of the EPEC type IV pili to retract is required for the breakdown of the host epithelial tight-junct
Autor:
Erin M. Bank, Oren Lotan, Kfir Ben-Harush, Naama Wiesel-Motiuk, Naomi Feinstein, Yosef Gruenbaum, Ohad Medalia, Rachel Barkan
Publikováno v:
Molecular Biology of the Cell
Mutations in human LMNA cause Emery-Dreifuss muscular dystrophy; however, a mechanistic link between the effect of mutations on lamin filament assembly and disease phenotype has not been established. Here we show that changes in lamin filament struct
Autor:
Esther Neufeld, Benjamin Podbilewicz, Yosef Gruenbaum, Naomi Feinstein, Ayelet Margalit, Katherine L. Wilson
Publikováno v:
The Journal of Cell Biology
Barrier to autointegration factor (BAF) binds double-stranded DNA, selected histones, transcription regulators, lamins, and LAP2–emerin–MAN1 (LEM) domain proteins. During early Caenorhabditis elegans embryogenesis, BAF-1 is required to organize c
Publikováno v:
Journal of Molecular Neuroscience. 10:17-29
The muscarinic acetylcholine receptors are important in a variety of physiological processes such as induction of secretion from various glands and regulation of pacemaker activity, muscle tone, and neurotransmission. To date, the muscarinic receptor
Autor:
Or Kakhlon, Tatsuo Terashima, Hasan O. Akman, Otto Baba, Salvatore DiMauro, Naomi Feinstein, Yan Liu, Hava Glickstein, Alexander Lossos
Publikováno v:
Journal of neurochemistry. 127(1)
Uncontrolled elongation of glycogen chains, not adequately balanced by their branching, leads to the formation of an insoluble, presumably neurotoxic, form of glycogen called polyglucosan. To test the suspected pathogenicity of polyglucosans in neuro
Publikováno v:
European Journal of Neuroscience. 7:742-752
In this report we show that alpha-latrotoxin from black widow spider venom is a potent activator of neurotransmitter release in synaptosomes from the Torpedo electric organ. Binding of the purified toxin (5 nM) to the synaptosomal fraction occurs alr
Autor:
Adam J. Zahand, Katherine L. Wilson, Rachel Barkan, Jun Liu, Yosef Gruenbaum, Kfir Sharabi, Erin Haithcock, Naomi Feinstein, Ayelet T. Lamm
Publikováno v:
Molecular Biology of the Cell
ETOC: Caenorhabditis elegans lacking both Ce-emerin and LEM-2 show that these proteins are essential for development of specific lineages, mitosis in somatic cells, and smooth muscle activity. Reduced life span and smooth muscle activity of LEM-2–n
Publikováno v:
Cell motility and the cytoskeleton. 66(10)
Specific mutations in human LMNA or loss of ZMPSTE26 activity cause abnormal processing of lamin A and early aging diseases, including Hutchinson Gilford progeria syndrome (HGPS). HGPS fibroblasts in culture undergo age-dependent progressive changes
The adult mammalian brain maintains a prominent stem cell niche in the subventricular zone supplying new neurons to the olfactory bulb. We examined the dynamics of synaptogenesis by imaging the formation and elimination of clusters of a postsynaptic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::279b1b964a90a0cd2402557885662fdd
https://europepmc.org/articles/PMC6664905/
https://europepmc.org/articles/PMC6664905/