Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Naomi Curimjee"'
Autor:
Caitlin A. Nichols, William J. Gibson, Meredith S. Brown, Jack A. Kosmicki, John P. Busanovich, Hope Wei, Laura M. Urbanski, Naomi Curimjee, Ashton C. Berger, Galen F. Gao, Andrew D. Cherniack, Sirano Dhe-Paganon, Brenton R. Paolella, Rameen Beroukhim
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
In tumors, hundreds of genes can undergo loss of heterozygosity (LOH). Here, the authors investigate the potential for this LOH as a class of non-driver cancer vulnerabilities.
Externí odkaz:
https://doaj.org/article/86a1e531ffce47339d04b2ee5dc0b8e0
Autor:
Ashton C. Berger, John P. Busanovich, Naomi Curimjee, Hope Wei, Sirano Dhe-Paganon, Jack A. Kosmicki, Meredith S. Brown, Andrew D. Cherniack, Rameen Beroukhim, Galen F. Gao, Brenton R. Paolella, Caitlin A. Nichols, Laura M. Urbanski, William J. Gibson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
Alterations in non-driver genes represent an emerging class of potential therapeutic targets in cancer. Hundreds to thousands of non-driver genes undergo loss of heterozygosity (LOH) events per tumor, generating discrete differences between tumor and