Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Naomi C. Wake"'
Autor:
Dean Gentle, Richard C. Trembath, Eamonn R. Maher, Farida Latif, Mariam Jafri, Naomi C. Wake, Tom L. Blundell, Astrid Weber, Michael A. Simpson, David B. Ascher, Mark R. Morris, Eleanor Rattenberry, Alan Donaldson, Emma R. Woodward, Douglas E. V. Pires
Publikováno v:
Cancer Discovery. 5:723-729
Familial renal cell carcinoma (RCC) is genetically heterogeneous and may be caused by mutations in multiple genes, including VHL, MET, SDHB, FH, FLCN, PTEN, and BAP1. However, most individuals with inherited RCC do not have a detectable germline muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e3d53b64a1ea1f7c421c3d82371ba5
https://doi.org/10.1158/2159-8290.cd-14-1096
https://doi.org/10.1158/2159-8290.cd-14-1096
Autor:
Johanna Dieguez Navas, John Watkinson, Patrick J. Morrison, Martin L. Read, Christopher McCabe, Eamonn R. Maher, Neil V. Morgan, Mercedes Robledo, Eric Y. Lian, Dom Mcmullan, Stan B. Sidhu, Emma R. Woodward, Fiona S. Togneri, Joel Smith, Beth Bradshaw, Trevor Cole, Jon Hoffman, Lois M. Mulligan, Vicki Smith, Naomi C. Wake, Justin S. Gundara, Rachel M. Brown, Richard C. Trembath, Christopher Campbell, Yvonne Wallis, Michael A. Simpson, Fiona Eatock, Susan Stewart
Familial medullary thyroid cancer (MTC) and its precursor, C cell hyperplasia (CCH), is associated with germline RET mutations causing multiple endocrine neoplasia type 2. However, some rare families with apparent MTC/CCH predisposition do not have a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e774a5c94f9d1970ddf7cc55e6a173
https://www.repository.cam.ac.uk/handle/1810/254346
https://www.repository.cam.ac.uk/handle/1810/254346
Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility
Autor:
Irene Stolte-Dijkstra, Eamonn R. Maher, John M. Opitz, Ger J. M. Pruijn, Harmeet Gill, Trevor Cole, Giovanni Neri, Patrick Rump, Mark R. Morris, Farida Latif, Salwati Shuib, Dean Gentle, Anthonie J. van Essen, Dewi Astuti, Raymond H.J. Staals, Wendy N. Cooper, Naomi C. Wake, Graham A Fews, Christopher J. Ricketts, Richard A. van Lingen, Ferenc Müller
Publikováno v:
Nature Genetics, 44(3), 277-U75. Nature Publishing Group
Nature Genetics, 44, 277-284
Nature Genetics, 44, 3, pp. 277-284
Nature Genetics, 44, 277-284
Nature Genetics, 44, 3, pp. 277-284
Perlman syndrome is a congenital overgrowth syndrome inherited in an autosomal recessive manner that is associated with Wilms tumor susceptibility. We mapped a previously unknown susceptibility locus to 2q37.1 and identified germline mutations in DIS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad013294c966078d7e15ae511f4a1418
https://doi.org/10.1038/ng.1071
https://doi.org/10.1038/ng.1071
Autor:
Christopher M. Bunce, Jonathan P. Ride, Claire Pearce, Naomi C. Wake, Jane Birtwistle, James K. Chipman, Rachel E. Hayden, Farhat L. Khanim, Nicholas J. Davies, Richard M. Green, Heinrich Schrewe
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 662:67-74
The aldo-keto reductase AKR1C3, has been shown to regulate myelopoiesis via its ability to metabolise prostaglandin D2 (PGD2). Other studies have demonstrated the oxidative activation of polycyclic aromatic hydrocarbon (PAH) procarcinogens by AKR1C3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876da9ef67bd0de8e875f4e96107542a
https://doi.org/10.1016/j.mrfmmm.2008.12.010
https://doi.org/10.1016/j.mrfmmm.2008.12.010
Autor:
Naomi C. Wake, Emy Bosseboeuf, Eamonn R. Maher, Martin L. Read, Vicki Smith, Christopher McCabe, Emma R. Woodward, John Watkinson, Yvonne Wallis, Joel Smith
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39620591f5884e5825bed7b6a7574653
https://doi.org/10.1530/endoabs.38.oc5.1
https://doi.org/10.1530/endoabs.38.oc5.1
Autor:
Martin L. Read, Christopher McCabe, Yvonne Wallis, Neil V. Morgan, Vicki Smith, Joel Smith, Emma R. Woodward, Eamonn R. Maher, Naomi C. Wake, John Watkinson
Publikováno v:
European Journal of Cancer. 61:S20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd30d4fdd2323ee2c768f396641dc33a
https://doi.org/10.1016/s0959-8049(16)61059-6
https://doi.org/10.1016/s0959-8049(16)61059-6
Autor:
Emma R. Woodward, Eamonn R. Maher, Michael D Brown, Farida Latif, Dean Gentle, Christopher J. Ricketts, Noel W. Clarke, Naomi C. Wake, Mark R. Morris
Publikováno v:
Ricketts, C J, Morris, M R, Gentle, D, Brown, M, Wake, N, Woodward, E R, Clarke, N, Latif, F & Maher, E R 2012, ' Genome-wide CpG island methylation analysis implicates novel genes in the pathogenesis of renal cell carcinoma ', Epigenetics : official journal of the DNA Methylation Society, vol. 7, no. 3, pp. 278-290 . https://doi.org/10.4161/epi.7.3.19103
Ricketts, C J, Morris, M R, Gentle, D, Brown, M, Wake, N, Woodward, E R, Clarke, N, Latif, F & Maher, E R 2012, ' Genome-wide CpG island methylation analysis implicates novel genes in the pathogenesis of renal cell carcinoma ', Epigenetics: official journal of the DNA Methylation Society, vol. 7, no. 3, pp. 278-290 . https://doi.org/10.4161/epi.7.3.19103
Ricketts, C J, Morris, M R, Gentle, D, Brown, M, Wake, N, Woodward, E R, Clarke, N, Latif, F & Maher, E R 2012, ' Genome-wide CpG island methylation analysis implicates novel genes in the pathogenesis of renal cell carcinoma ', Epigenetics: official journal of the DNA Methylation Society, vol. 7, no. 3, pp. 278-290 . https://doi.org/10.4161/epi.7.3.19103
In order to identify novel candidate tumor suppressor genes (TSGs) implicated in renal cell carcinoma (RCC), we performed genome-wide methylation profiling of RCC using the HumanMethylation27 BeadChips to assess methylation at >14,000 genes. Two hund
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6769b45a5b299ab69c83e20dcf98af
https://doi.org/10.4161/epi.7.3.19103
https://doi.org/10.4161/epi.7.3.19103