Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.

Autor: Nancy L Saccone, Robert C Culverhouse, Tae-Hwi Schwantes-An, Dale S Cannon, Xiangning Chen, Sven Cichon, Ina Giegling, Shizhong Han, Younghun Han, Kaisu Keskitalo-Vuokko, Xiangyang Kong, Maria Teresa Landi, Jennie Z Ma, Susan E Short, Sarah H Stephens, Victoria L Stevens, Lingwei Sun, Yufei Wang, Angela S Wenzlaff, Steven H Aggen, Naomi Breslau, Peter Broderick, Nilanjan Chatterjee, Jingchun Chen, Andrew C Heath, Markku Heliövaara, Nicole R Hoft, David J Hunter, Majken K Jensen, Nicholas G Martin, Grant W Montgomery, Tianhua Niu, Thomas J Payne, Leena Peltonen, Michele L Pergadia, John P Rice, Richard Sherva, Margaret R Spitz, Juzhong Sun, Jen C Wang, Robert B Weiss, William Wheeler, Stephanie H Witt, Bao-Zhu Yang, Neil E Caporaso, Marissa A Ehringer, Tim Eisen, Susan M Gapstur, Joel Gelernter, Richard Houlston, Jaakko Kaprio, Kenneth S Kendler, Peter Kraft, Mark F Leppert, Ming D Li, Pamela A F Madden, Markus M Nöthen, Sreekumar Pillai, Marcella Rietschel, Dan Rujescu, Ann Schwartz, Christopher I Amos, Laura J Bierut

Publikováno v: PLoS Genetics, Vol 6, Iss 8, p e1001053 (2010)

Recently, genetic association findings for nicotine dependence, smoking behavior, and smoking-related diseases converged to implicate the chromosome 15q25.1 region, which includes the CHRNA5-CHRNA3-CHRNB4 cholinergic nicotinic receptor subunit genes.

Externí odkaz: https://doaj.org/article/ec22c1d8d2fc40a4a6583be408b4a69a

Supplementary Table 2 from The CHRNA5-CHRNA3-CHRNB4 Nicotinic Receptor Subunit Gene Cluster Affects Risk for Nicotine Dependence in African-Americans and in European-Americans

Autor: Laura J. Bierut, Alison M. Goate, John P. Rice, Meng Wu, Joseph Henry Steinbach, Anthony L. Hinrichs, Louis Fox, Robert C. Culverhouse, John Budde, Weimin Duan, Lingwei Sun, Richard A. Grucza, Scott F. Saccone, Dorothy Hatsukami, Eric O. Johnson, Naomi Breslau, Jen C. Wang, Nancy L. Saccone

Supplementary Table 2 from The CHRNA5-CHRNA3-CHRNB4 Nicotinic Receptor Subunit Gene Cluster Affects Risk for Nicotine Dependence in African-Americans and in European-Americans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244502039fc6dfb3a7c973f24e870061
https://doi.org/10.1158/0008-5472.22378976.v1

Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression

Autor: Lucy Bowes, Richard Burns, Alex Hatzimanolis, Gonneke Willemsen, Martin A. Kennedy, Kathryn J. Lester, Katerina A.B. Gawronski, Udo Dannlowski, Alison Goate, Carolyn Coffey, Matthias Nauck, David Stacey, Ricardo Araya, Frank Bellivier, Cecilia Åslund, Catherine Toben, Catharine Jawahar, Karen Ritchie, Emilie Olié, Gyorgy Bagdy, Nicholas G. Martin, Robert Culverhouse, Isabelle Jaussent, Peter Petschner, Eric O. Johnson, Nancy L. Saccone, Sandra Villafuerte, Mohamed Lajnef, John I. Nurnberger, Volker Arolt, Laura Mandelli, Philippe Courtet, Henry Völzke, Yinjiao Ma, Craig A. Olsson, Y. Tian, Bernhard T. Baune, Keriann Little, Wouter J. Peyrot, Nicholas W.J. Wainwright, Helen L. Fisher, Brenda W.J.H. Penninx, Manfred Laucht, E.J.C. de Geus, Jan Smit, Sébastien Guillaume, J. M. Scheid, S Van der Auwera, Christian Schwahn, Hans-Jörgen Grabe, Kent W. Nilsson, Xenia Gonda, Dana A. Glei, Gabriella Juhasz, Bruno Etain, C. Holzman, Maxine Weinstein, Thalia C. Eley, Kaarin J. Anstey, Marco Sarchiapone, John Francis William Deakin, Naomi Breslau, P. G. Surtees, John Kramer, J-J Hottenga, Enda M. Byrne, Marcus R. Munafò, Christine Jennen-Steinmetz, Laura J. Bierut, Albertine J. Oldehinkel, Noreen Goldman, Dorret I. Boomsma, Simon Easteal, Margit Burmeister, John Horwood, George C Patton, Tobias Banaschewski, David M. Fergusson, Amy C. Horton, Mary A. Whooley, J. C. Wang, Esther Nederhof, H. M. Zu Schwabedissen, Grant C.B. Sinnamon, Christian Otte, Sarah Cohen-Woods, Ian M. Anderson, William L. Coventry, Tracy Air, Christel M. Middeldorp, Nicholas C. Stefanis, Alessandro Serretti, Johan Ormel

Publikováno v: Culverhouse, R C, Saccone, N L, Horton, A C, Ma, Y, Anstey, K J, Banaschewski, T, Burmeister, M, Cohen-Woods, S, Etain, B, Fisher, H L, Goldman, N, Guillaume, S, Horwood, J, Juhasz, G, Lester, K J, Mandelli, L, Middeldorp, C M, Olié, E, Villafuerte, S, Air, T M, Araya, R, Bowes, L, Burns, M R, Byrne, E M, Coffey, J C, Coventry, W L, Gawronski, K A B, Glei, D, Hatzimanolis, A, Hottenga, J-J, Jaussent, I, Jawahar, C, Jennen-Steinmetz, C, Kramer, J R, Lajnef, M, Little, K, Meyer zu Schwabedissen, H, Nauck, M, Nederhof, E, Petschner, P, Peyrot, W J, Schwahn, C, Sinnamon, G, Stacey, D, Tian, Y, Toben, C, Van der Auwera, S, Wainwright, N W, Wang, J-C, Willemsen, G, Anderson, I M, Arolt, V, Åslund, C, Bagdy, G, Baune, B T, Bellivier, F, Boomsma, D I, Courtet, P, Dannlowski, U, de Geus, E J C, Deakin, J F W, Easteal, S, Eley, T C, Fergusson, D M, Goate, A M, Gonda, X, Grabe, H J, Holzman, C, Johnson, E O, Kennedy, D M, Laucht, M, Martin, N G, Munafò, M R, Nilsson, K W, Oldehinkel, A J, Olsson, C A, Ormel, J, Otte, C, Patton, G C, Penninx, B W J H, Ritchie, K, Sarchiapone, M, Scheid, J M, Serretti, A, Smit, J H, Stefanis, N C, Surtees, P G, Völzke, H, Weinstein, M, Whooley, M A, Nurnberger, J I, Breslau, N & Bierut, L J 2018, ' Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression ', Molecular Psychiatry, vol. 23, no. 1, pp. 133-142 . https://doi.org/10.1038/mp.2017.44
Culverhouse, R C, Saccone, N L, Horton, A C, Ma, Y, Anstey, K J, Banaschewski, T, Burmeister, M, Cohen-Woods, S, Etain, B, Fisher, H L, Goldman, N, Guillaume, S, Horwood, J, Juhasz, G, Lester, K J, Mandelli, L, Middeldorp, C M, Olié, E, Villafuerte, S, Air, T M, Araya, R, Bowes, L, Burns, R, Byrne, E M, Coffey, C, Coventry, W L, Gawronski, K A B, Glei, D, Hatzimanolis, A, Hottenga, J-J, Jaussent, I, Jawahar, C, Jennen-Steinmetz, C, Kramer, J R, Lajnef, M, Little, K, Zu Schwabedissen, H M, Nauck, M, Nederhof, E, Petschner, P, Peyrot, W J, Schwahn, C, Sinnamon, G, Stacey, D, Tian, Y, Toben, C, Van der Auwera, S, Wainwright, N, Wang, J-C, Willemsen, G, Anderson, I M, Arolt, V, Åslund, C, Bagdy, G, Baune, B T, Bellivier, F, Boomsma, D I, Courtet, P, Dannlowski, U, de Geus, E J C, Deakin, J F W, Easteal, S, Eley, T, Fergusson, D M, Goate, A M, Gonda, X, Grabe, H J, Holzman, C, Johnson, E O, Kennedy, M, Laucht, M, Martin, N G, Munafò, M R, Nilsson, K W, Oldehinkel, A J, Olsson, C A, Ormel, J, Otte, C, Patton, G C, Penninx, B W J H, Ritchie, K, Sarchiapone, M, Scheid, J M, Serretti, A, Smit, J H, Stefanis, N C, Surtees, P G, Völzke, H, Weinstein, M, Whooley, M, Nurnberger, J I, Breslau, N & Bierut, L J 2017, ' Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression ', Molecular Psychiatry, vol. 23, pp. 133–142 . https://doi.org/10.1038/mp.2017.44
Molecular Psychiatry, 23, 133-142. Nature Publishing Group
Molecular Psychiatry, 23(1), 133-142. Nature Publishing Group
Culverhouse, R C, Saccone, N L, Horton, A C, Anstey, K J, Banaschewski, T, Burmeister, M, Cohen-Woods, S, Etain, B, Fisher, H L, Goldman, N, Guillaume, S, Horwood, J, Juhasz, G, Lester, K J, Mandelli, L, Middeldorp, C M, Olié, E, Villafuerte, S, Air, T M, Araya, R, Bowes, L, Byrne, E M, Coffey, C, Coventry, W L, Gawronski, K A B, Glei, D, Hatzimanolis, A, Hottenga, J-J, Jaussent, I, Jawahar, C, Jennen-Steinmetz, C, Kramer, J R, Lajnef, M, Zu Schwabedissen, H M, Nauck, M, Nederhof, E, Petschner, P, Peyrot, W J, Schwahn, C, Sinnamon, G, Tian, Y, Toben, C, Van der Auwera, S, Wainwright, N, Willemsen, G, Anderson, I M, Arolt, V, Åslund, C, Bagdy, G, Baune, B T, Bellivier, F, Boomsma, D I, Courtet, P, Dannlowski, U, de Geus, E J C, Deakin, J F W, Easteal, S, Eley, T, Fergusson, D M, Goate, A M, Gonda, X, Grabe, H J, Holzman, C, Laucht, M, Munafò, M R, Nilsson, K W, Oldehinkel, A J, Olsson, C A, Ormel, J, Otte, C, Patton, G C, Penninx, B W J H, Ritchie, K, Sarchiapone, M, Scheid, J M, Serretti, A, Stefanis, N C, Surtees, P G, Völzke, H, Weinstein, M, Whooley, M, Nurnberger, J I, Breslau, N & Bierut, L J 2018, ' Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression ', Molecular Psychiatry, vol. 23, no. 1, pp. 133-142 . https://doi.org/10.1038/mp.2017.44
Molecular Psychiatry
Molecular Psychiatry, Nature Publishing Group, 2018, 23 (1), pp.133--142. ⟨10.1038/mp.2017.44⟩
Culverhouse, R C, Saccone, N L, Horton, A C, Ma, Y, Anstey, K J, Banaschewski, T, Burmeister, M, Cohen-Woods, S, Etain, B, Fisher, H L, Goldman, N, Guillaume, S, Horwood, J, Juhasz, G, Lester, K J, Mandelli, L, Middeldorp, C M, Olié, E, Villafuerte, S, Air, T M, Araya, R, Bowes, L, Burns, R, Byrne, E M, Coffey, C, Coventry, W L, Gawronski, K A B, Glei, D, Hatzimanolis, A, Hottenga, J J, Jaussent, I, Jawahar, C, Jennen-Steinmetz, C, Kramer, J R, Lajnef, M, Little, K, Zu Schwabedissen, H M, Nauck, M, Nederhof, E, Petschner, P, Peyrot, W J, Schwahn, C, Sinnamon, G, Stacey, D, Tian, Y, Toben, C, Van Der Auwera, S, Wainwright, N, Wang, J C, Willemsen, G, Anderson, I M, Arolt, V, Aslund, C, Bagdy, G, Baune, B T, Bellivier, F, Boomsma, D I, Courtet, P, Dannlowski, U, De Geus, E J C, Deakin, J F W, Easteal, S, Eley, T, Fergusson, D M, Goate, A M, Gonda, X, Grabe, H J, Holzman, C, Johnson, E O, Kennedy, M, Laucht, M, Martin, N G, Munafò, M R, Nilsson, K W, Oldehinkel, A J, Olsson, C A, Ormel, J, Otte, C, Patton, G C, Penninx, B W J H, Ritchie, K, Sarchiapone, M, Scheid, J M, Serretti, A, Smit, J H, Stefanis, N C, Surtees, P G, Völzke, H, Weinstein, M, Whooley, M, Nurnberger, J I, Breslau, N & Bierut, L J 2018, ' Collaborative meta-Analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression ', Molecular Psychiatry, vol. 23, no. 1, pp. 133-142 . https://doi.org/10.1038/mp.2017.44
Molecular psychiatry

The hypothesis that the S allele of the 5-HTTLPR serotonin transporter promoter region is associated with increased risk of depression, but only in individuals exposed to stressful situations, has generated much interest, research and controversy sin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6e272421cf2db41f79fb4339d34947
https://hdl.handle.net/1871.1/a867d0ad-f3ba-415d-8864-2e5179ee0216

Latent classes of childhood trauma exposure predict the development of behavioral health outcomes in adolescence and young adulthood

Autor: Carla L. Storr, Naomi Breslau, Shelley R. Hart, Elizabeth D. Ballard, Holly C. Wilcox, Rashelle J. Musci, K. Van Eck

Publikováno v: Psychological Medicine. 45:3305-3316

BackgroundTo develop latent classes of exposure to traumatic experiences before the age of 13 years in an urban community sample and to use these latent classes to predict the development of negative behavioral outcomes in adolescence and young adult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6690817b1e75fc2ed40fa18ffe2ad693
https://doi.org/10.1017/s0033291715001300

Multiple distinct CHRNB3-CHRNA6 variants are genetic risk factors for nicotine dependence in African Americans and European Americans

Autor: Dorothy K. Hatsukami, Naomi Breslau, Brooke Sadler, Alison Goate, Laura J. Bierut, Andrew Brooks, Robert Culverhouse, Marc A. Schuckit, Jay A. Tischfield, Victor Hesselbrock, Nancy L. Saccone, Eric O. Johnson

Publikováno v: Addiction. 109:814-822

Aims Studies have shown association between common variants in the α6-β3 nicotinic receptor subunit gene cluster and nicotine dependence in European ancestry populations. We investigate whether this generalizes to African Americans, whether the ass

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2730b9572835697645317e52277af838
https://doi.org/10.1111/add.12478