Figure S6 from TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis

Autor: Paul J. Grippo, Barbara Jung, Hidayatullah G. Munshi, David J. Bentrem, Deyu Fang, David W. Dawson, Boris Pasche, Rosa Hwang, Naomi Akagi, Andrew M. Diaz, Elizabeth A. Wayne, Emman Mascariñas, Brian DeCant, Daniel R. Principe

Figure S6. Global TGFBR-Deficiency does not Alter Non-Peripheral Tregs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0048aca13df700f66e9f2843438082f5
https://doi.org/10.1158/0008-5472.22411965.v1

Data from TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis

Autor: Paul J. Grippo, Barbara Jung, Hidayatullah G. Munshi, David J. Bentrem, Deyu Fang, David W. Dawson, Boris Pasche, Rosa Hwang, Naomi Akagi, Andrew M. Diaz, Elizabeth A. Wayne, Emman Mascariñas, Brian DeCant, Daniel R. Principe

In early pancreatic carcinogenesis, TGFβ acts as a tumor suppressor due to its growth-inhibitory effects in epithelial cells. However, in advanced disease, TGFβ appears to promote tumor progression. Therefore, to better understand the contributions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b2d20fdfcd03c23f3ba4c88ae7a4b58
https://doi.org/10.1158/0008-5472.c.6508338.v1

SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood

Autor: Michael P. Busch, Mars Stone, Kent Truong, Edward Thornborrow, Alicia Sotomayor-Gonzalez, Jeffrey D. Whitman, Claudia Sanchez San Martin, Jill Hakim, Chuanyi M. Lu, Naomi Akagi, Elaine Hsu, Charles Y. Chiu, Daniel Qazi, Sagar P. Bapat, Susan L. Stramer, Gregory M. Goldgof, Venice Servellita, Li Du, Fariba Alazzeh, Mary A. Rodgers, Neil M. Neumann, Sergej Franz, Nancy K. Hills, Joanna Balcerek, Candace Wang, Kevin Reyes, John Hackett, Sandra Pearce, Dustin R. Glasner, Satish K. Pillai, Andrea Granados, Andrew G. Levine, Lucy M. Han, John Prostko, Steve Miller, Valerie Green, Ching Ying Oon, Wei Gu, Kirk Sujishi, Yale A. Santos, Brian R. Shy, David N. Nguyen, Dianna Ng, Graham Simmons, Phillip C. Williamson, Theodore W. Kurtz, Lori Pham, Kelly E. Coller, Brian Custer

Publikováno v: Nature communications, vol 11, iss 1
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
medRxiv
article-version (status) pre
article-version (number) 2

Given the limited availability of serological testing to date, the seroprevalence of SARS-CoV-2-specific antibodies in different populations has remained unclear. Here, we report very low SARS-CoV-2 seroprevalence in two San Francisco Bay Area popula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0fc0e7a75357cb212d49a53b38b46d3
https://escholarship.org/uc/item/8430p046

Rapid Improvement in Gemcitabine-associated Thrombotic Microangiopathy After a Single Dose of Eculizumab: Case Report and Review of the Literature

Autor: Lloyd E. Damon, Andrew H. Ko, Naomi Akagi, Zoltan Laszik, Shohei Burns

Publikováno v: Anticancer research. 40(7)

We present here the case of a 39-year-old man with metastatic pancreatic carcinoma receiving chemotherapy with the combination of gemcitabine and nab-paclitaxel as part of a clinical trial. Despite an impressive response to therapy, he ultimately dev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af1f69e617affbd7feb8c6872d7ca607
https://pubmed.ncbi.nlm.nih.gov/32620643

TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis

Autor: Emman Mascariñas, Naomi Akagi, Deyu Fang, Elizabeth A. Wayne, Hidayatullah G. Munshi, Brian DeCant, Paul J. Grippo, David W. Dawson, Rosa F. Hwang, Boris Pasche, Barbara Jung, Andrew M. Diaz, David J. Bentrem, Daniel R. Principe

Publikováno v: Cancer Research. 76:2525-2539

In early pancreatic carcinogenesis, TGFβ acts as a tumor suppressor due to its growth-inhibitory effects in epithelial cells. However, in advanced disease, TGFβ appears to promote tumor progression. Therefore, to better understand the contributions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1f0a29d1bb644c4d18adb2c8dc5d90
https://doi.org/10.1158/0008-5472.can-15-1293