Zobrazeno 1 - 10
of 388
pro vyhledávání: '"Naomi, Nakagata"'
Autor:
Yuta Ishizuka, Satohiro Nakao, Tsutomu Kamisako, Katsuma Yamaga, Naomi Nakagata, Hiroyoshi Ishizaki, Toru Takeo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract The cryopreservation of rat embryos is useful for efficiently archiving rat resources in bioresource repositories. The cryopreserved fertilized oocytes can be quickly reanimated to rats with homozygous mutations using embryo transfer. In add
Externí odkaz:
https://doaj.org/article/ed4839877c5a4a6281293419d5904b1f
Autor:
Rahmawati Aisyah, Noriyasu Ohshima, Daiki Watanabe, Yoshiko Nakagawa, Tetsushi Sakuma, Felix Nitschke, Minako Nakamura, Koji Sato, Kaori Nakahata, Chihiro Yokoyama, Charlotte R. Marchioni, Thanutchaporn Kumrungsee, Takahiko Shimizu, Yusuke Sotomaru, Toru Takeo, Naomi Nakagata, Takashi Izumi, Shinji Miura, Berge A. Minassian, Takashi Yamamoto, Masanobu Wada, Noriyuki Yanaka
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Glycerophosphocholine (GPC) is an important precursor for intracellular choline supply in phosphatidylcholine (PC) metabolism. GDE5/Gpcpd1 hydrolyzes GPC into choline and glycerol 3-phosphate; this study aimed to elucidate its physiological
Externí odkaz:
https://doaj.org/article/cb2483d665d74748b78e1920755b6628
Autor:
Katsuma YAMAGA, Satohiro NAKAO, Nobuyuki MIKODA, Jorge Mario SZTEIN, Naomi NAKAGATA, Toru TAKEO
Publikováno v:
The Journal of Reproduction and Development, Vol 70, Iss 2, Pp 131-137 (2024)
Cold transport of the cauda epididymides is a useful technique for shipping laboratory rat sperm. Cold transport of rat sperm avoids potential risks of microbiological infection, animal escape or death, and animal welfare issues. Previously, we repor
Externí odkaz:
https://doaj.org/article/45abf663ee8648a78d934ba8b1618e99
Publikováno v:
The Journal of Reproduction and Development, Vol 70, Iss 2, Pp 123-130 (2024)
Genetically modified rats are valuable models in human disease research. We recently developed an improved system for rat sperm cryopreservation and in vitro fertilization (IVF) that facilitates the efficient production and preservation of geneticall
Externí odkaz:
https://doaj.org/article/b035477e0d91437eb1856a4064ad4a07
Autor:
Yusei Yamada, Madoka Fukaura‐Nishizawa, Asami Nishiyama, Akira Ishii, Tatsuya Kawata, Aina Shirakawa, Mayuko Tanaka, Yuki Kondo, Toru Takeo, Naomi Nakagata, Toru Miwa, Hiroki Takeda, Yorihisa Orita, Keiichi Motoyama, Taishi Higashi, Hidetoshi Arima, Takahiro Seki, Yuki Kurauchi, Hiroshi Katsuki, Katsumi Higaki, Kentaro Minami, Naoki Yoshikawa, Ryuji Ikeda, Muneaki Matsuo, Tetsumi Irie, Yoichi Ishitsuka
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 8, Pp n/a-n/a (2023)
Abstract Background Niemann–Pick disease type C (NPC) is a fatal neurodegenerative disorder caused by abnormal intracellular cholesterol trafficking. Cyclodextrins (CDs), the most promising therapeutic candidates for NPC, but with concerns about ot
Externí odkaz:
https://doaj.org/article/4e90738b28c44e4c9ddaf53a1c5805b3
Autor:
Takafumi Utsunomiya, Tatsuma Yao, Hiroko Itoh, Yufuko Kai, Yoko Kumasako, Miwa Setoguchi, Naomi Nakagata, Osamu Tsutsumi, Kaoru Yanagida, Yoshinori Fukuda, Tomohiro Kono
Publikováno v:
Fertility & Reproduction, Vol 05, Iss 04, Pp 318-318 (2023)
Background and Aims: Although culture conditions were recognized as key points, an optimal culture medium formulation, which closely resembles natural human oviduct fluid (HOF), has not been obtained yet. Our aim is to make an ideal embryo culture me
Externí odkaz:
https://doaj.org/article/89e8c7ec69df4d7aaeca1f5a71474082
Autor:
Satohiro Nakao, Kotono Ito, Chihiro Sugahara, Hitomi Watanabe, Gen Kondoh, Naomi Nakagata, Toru Takeo
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281330 (2023)
The number of sperm that reaches the oocytes in mammalian species is limited. In mice, 8-10 oocytes are ovulated, a similar number of sperm reaches the oocytes, and nearly all oocytes are fertilized via natural mating. Meanwhile, our improved superov
Externí odkaz:
https://doaj.org/article/f9318075d01941a88ebea707ed0c06be
Quercetin-treated rat sperm enables refrigerated transport with motility and fertility for five days
Autor:
Katsuma Yamaga, Satohiro Nakao, Nobuyuki Mikoda, Hidetaka Yoshimoto, Ena Nakatsukasa, Naomi Nakagata, Toru Takeo
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Shipment of laboratory rats between animal facilities is frequently performed using special containers. However, the shipment of live animals is associated with potential risks of infectious diseases, escape and death during shipment and ani
Externí odkaz:
https://doaj.org/article/d9562981f159469689a0ae9bc2299f33
Autor:
Shinichi WATANABE, Megumi MIURA, Hiromi MORITA, Moeka NISHI, Shin-ichi YOKOTA, Shosaku HATTORI, Hiromichi MATSUMOTO, Emiko FUKUI, Ken Takeshi KUSAKABE, Masanori OCHI, Naomi NAKAGATA, Yasuo KISO, Chieko KAI, Midori YOSHIZAWA
Publikováno v:
The Journal of Reproduction and Development, Vol 67, Iss 4, Pp 265-272 (2021)
Advanced reproductive technologies are being applied for the propagation of squirrel monkeys, to ensure their preservation as a genetic resource and the effective use of their gametes in the future. In the present study, oocytes and spermatozoa were
Externí odkaz:
https://doaj.org/article/f8b9de966608437b9b04300b81979121
Autor:
Hiroshi Watanabe, Rui Fujimura, Yuto Hiramoto, Ryota Murata, Kento Nishida, Jing Bi, Tadashi Imafuku, Hisakazu Komori, Hitoshi Maeda, Ayumi Mukunoki, Toru Takeo, Naomi Nakagata, Motoko Tanaka, Kazutaka Matsushita, Masafumi Fukagawa, Toru Maruyama
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The molecular mechanism for acute kidney injury (AKI) and its progression to chronic kidney disease (CKD) continues to be unclear. In this study, we investigated the pathophysiological role of the acute phase protein α1-acid glycoprotein (A
Externí odkaz:
https://doaj.org/article/39863770c8144052b17dfd1f72939b0f