Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Naoko Toyofuku"'
Autor:
Piyusha Mongia, Naoko Toyofuku, Ziyi Pan, Ran Xu, Yakumo Kinoshita, Keitaro Oki, Hiroki Takahashi, Yoshitoshi Ogura, Tetsuya Hayashi, Takuro Nakagawa
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Rad51 maintains genome integrity, whereas Rad52 causes non-canonical homologous recombination leading to gross chromosomal rearrangements (GCRs). Here we find that fission yeast Srr1/Ber1 and Skb1/PRMT5 promote GCRs at centromeres. Genetic a
Externí odkaz:
https://doaj.org/article/04436d1c7a394189943f565a4b8ec0e8
Publikováno v:
PLoS Genetics, Vol 17, Iss 7, p e1009671 (2021)
Gross chromosomal rearrangements (GCRs), including translocation, deletion, and inversion, can cause cell death and genetic diseases such as cancer in multicellular organisms. Rad51, a DNA strand exchange protein, suppresses GCRs by repairing spontan
Externí odkaz:
https://doaj.org/article/89a007c032634961b84e6246ff9712ec
Autor:
Piyusha Mongia, Naoko Toyofuku, Ziyi Pan, Ran Xu, Keitaro Oki, Hiroki Takahashi, Yoshitoshi Ogura, Tetsuya Hayashi, Takuro Nakagawa
Rad51 faithfully repairs DNA damage, whereas Rad52 promotes non-canonical homologous recombination leading to gross chromosomal rearrangements (GCRs). However, the GCR mechanism remains unclear. Here we find that fission yeast Srr1/Ber1 and Skb1/PRMT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c41aa760b235fe816b58cb605c41075b
https://doi.org/10.21203/rs.3.rs-2165921/v1
https://doi.org/10.21203/rs.3.rs-2165921/v1
Rad52 recombinase can cause gross chromosomal rearrangements (GCRs). However, the mechanism of Rad52-dependent GCRs remains unclear. Here, we show that fission yeast Rad8/HLTF facilitates Rad52-dependent GCRs through the ubiquitination of lysine 107
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b777cb3bdabc870567252db9b154912
https://doi.org/10.1101/2021.01.05.425428
https://doi.org/10.1101/2021.01.05.425428
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 17, Iss 7, p e1009671 (2021)
PLoS Genetics, Vol 17, Iss 7, p e1009671 (2021)
Gross chromosomal rearrangements (GCRs), including translocation, deletion, and inversion, can cause cell death and genetic diseases such as cancer in multicellular organisms. Rad51, a DNA strand exchange protein, suppresses GCRs by repairing spontan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b846d0ab36ebfffdabb0ea38faf159a3
https://doi.org/10.1371/journal.pgen.1009671
https://doi.org/10.1371/journal.pgen.1009671
Autor:
Minami Sagawa, Takahiro Inoue, Akiko K. Okita, Rei Matsuyama, Naoko Toyofuku, Faria Zafar, Tatsuro S. Takahashi, Takuro Nakagawa, Atsushi T. Onaka, Jie Su, Hisao Masukata, Takeshi Shitanda
Publikováno v:
Nucleic Acids Research
Centromeres consist of DNA repeats in many eukaryotes. Non-allelic homologous recombination (HR) between them can result in gross chromosomal rearrangements (GCRs). In fission yeast, Rad51 suppresses isochromosome formation that occurs between invert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f180d3a0a3879a93996aa4ebc2edb27e
https://pubmed.ncbi.nlm.nih.gov/27697832
https://pubmed.ncbi.nlm.nih.gov/27697832
Autor:
Onaka, Atsushi T., Naoko Toyofuku, Takahiro Inoue, Okita, Akiko K., Minami Sagawa, Jie Su, Takeshi Shitanda, Rei Matsuyama, Faria Zafar, Takahashi, Tatsuro S., Hisao Masukata, Takuro Nakagawa
Publikováno v:
Nucleic Acids Research; 12/15/2016, Vol. 44 Issue 22, p10744-10757, 14p