Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Naoko Orii"'
Autor:
Hideaki Hasegawa, Izuru Mizoguchi, Naoko Orii, Shinya Inoue, Yasuhiro Katahira, Toshihiko Yoneto, Mingli Xu, Toru Miyazaki, Takayuki Yoshimoto
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Among various cytokines, interleukin (IL)-12 family cytokines have very unique characteristics in that they are composed of two distinct subunits and these subunits are shared with each other. IL-23, one of the IL-12 family cytokines, consis
Externí odkaz:
https://doaj.org/article/88cfd12351954441be5fab9535e4e725
Autor:
Hideaki Hasegawa, Izuru Mizoguchi, Naoko Orii, Shinya Inoue, Yasuhiro Katahira, Toshihiko Yoneto, Mingli Xu, Toru Miyazaki, Takayuki Yoshimoto
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/d1117b1069064f01be449785aed5fab8
Autor:
Naoko Orii, Izuru Mizoguchi, Yukino Chiba, Hideaki Hasegawa, Mio Ohashi, Mingli Xu, Taro Nagai, Nakaba Ochiai, Yuki Mochizuki, Toshiyuki Owaki, Takayuki Yoshimoto
Publikováno v:
OncoImmunology, Vol 7, Iss 5 (2018)
Interleukin (IL)-27 is a multifunctional cytokine that belongs to the IL-6/IL-12 family and has potent antitumor activity through various mechanisms. Our novel findings indicate that IL-27 directly acts on hematopoietic stem cells and promotes their
Externí odkaz:
https://doaj.org/article/a964effe11f54bc38921a60a6811dbcc
Autor:
Shinya Inoue, Yasuhiro Katahira, Mingli Xu, Hideaki Hasegawa, Takayuki Yoshimoto, Toru Miyazaki, Toshihiko Yoneto, Naoko Orii, Izuru Mizoguchi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Scientific Reports
Scientific Reports
Among various cytokines, interleukin (IL)-12 family cytokines have very unique characteristics in that they are composed of two distinct subunits and these subunits are shared with each other. IL-23, one of the IL-12 family cytokines, consists of p19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b110f5b436fab1b8fd4568b6b1bdf5b2
https://doaj.org/article/88cfd12351954441be5fab9535e4e725
https://doaj.org/article/88cfd12351954441be5fab9535e4e725
Autor:
Mio Ohashi, Toshiyuki Owaki, Hideaki Hasegawa, Takayuki Yoshimoto, Yukino Chiba, Taro Nagai, Naoko Orii, Izuru Mizoguchi, Mingli Xu, Yasunori Miyamoto, Miyaka Sugahara
Publikováno v:
Cellular and Molecular Life Sciences. 75:1363-1376
Hematopoiesis is hierarchically orchestrated by a very small population of hematopoietic stem cells (HSCs) that reside in the bone-marrow niche and are tightly regulated to maintain homeostatic blood production. HSCs are predominantly quiescent, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ba53a7f031789d7a10226451bf136c
https://doi.org/10.1007/s00018-017-2724-5
https://doi.org/10.1007/s00018-017-2724-5
Autor:
Chiaki Kawana, Naoko Orii, Yukino Chiba, Kouji Matsushima, Katsuko Sudo, Masahiko Kuroda, Hideaki Hasegawa, Mio Ohashi, Koji Fujita, Mingli Xu, Shin-ichi Hashimoto, Izuru Mizoguchi, Takayuki Yoshimoto, Shinya Inoue
Publikováno v:
J Clin Invest
Epstein-Barr virus–induced gene 3 (EBI3) is a subunit common to IL-27, IL-35, and IL-39. Here, we explore an intracellular role of EBI3 that is independent of its function in cytokines. EBI3-deficient naive CD4(+) T cells had reduced IFN-γ product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ab240f5d8ec2ec14d09ddb330010b2
https://pubmed.ncbi.nlm.nih.gov/32809973
https://pubmed.ncbi.nlm.nih.gov/32809973
Autor:
Takayuki Yoshimoto, Yukino Chiba, Hideaki Hasegawa, Mio Ohashi, Taro Nagai, Mingli Xu, Nakaba Ochiai, Naoko Orii, Izuru Mizoguchi, Toshiyuki Owaki, Yuki Mochizuki
Publikováno v:
OncoImmunology, Vol 7, Iss 5 (2018)
Interleukin (IL)-27 is a multifunctional cytokine that belongs to the IL-6/IL-12 family and has potent antitumor activity through various mechanisms. Our novel findings indicate that IL-27 directly acts on hematopoietic stem cells and promotes their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e42f58e22caf58e132fc565fdfd31f
https://doi.org/10.1080/2162402x.2017.1421892
https://doi.org/10.1080/2162402x.2017.1421892
Autor:
Izuru Mizoguchi1, Mio Ohashi1, Hideaki Hasegawa1, Yukino Chiba1, Naoko Orii1, Shinya Inoue1, Chiaki Kawana1, Mingli Xu1, Katsuko Sudo2, Koji Fujita3, Masahiko Kuroda3, Shin-ichi Hashimoto4, Kouji Matsushima5, Takayuki Yoshimoto1, Mizoguchi, Izuru6, Ohashi, Mio6, Hasegawa, Hideaki6, Chiba, Yukino6, Orii, Naoko6, Inoue, Shinya6
Publikováno v:
Journal of Clinical Investigation. Nov2020, Vol. 130 Issue 11, p6124-6140. 17p. 2 Color Photographs, 1 Black and White Photograph, 5 Graphs.