Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Naoko Matsuura"'
Autor:
Rie Nomizu, Toshiko Sakai, Taemi Murase, Ai Taira, Naoko Matsuura, Azusa Fukuoka, Ai Aoi, Shigenori Ito
Publikováno v:
Cardiovascular Intervention and Therapeutics Japanese Edition. 4:133-139
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb8691d90b8d462057093100271d3566
https://doi.org/10.15245/cvit.4.133
https://doi.org/10.15245/cvit.4.133
Autor:
Motohiko Kometani, Ichiro Umemura, Naoko Matsuura, Ikuo Sugiyama, Yuko Hitomi, Takeru Ehara, Takatoshi Kosaka, Keiichi Masuya, Naoki Teno, Genji Iwasaki, Noriko Uchiyama, Kazuhiro Toriyama, Osamu Irie, Takahiro Miyake, Hiroaki Fukaya, Kazuhiko Nonomura
Publikováno v:
Journal of Medicinal Chemistry. 51:5459-5462
On the basis of the pyrrolopyrimidine core structure that was previously discovered, cathepsin K inhibitors having a spiro amine at the P3 have been explored to enhance the target, bone marrow, tissue distribution. Several spiro structures were ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bdb3283586e240e5700f0f269569870
https://doi.org/10.1021/jm800626a
https://doi.org/10.1021/jm800626a
Autor:
Ha-Soon, Choi, Zhicheng, Wang, Wendy, Richmond, Xiaohui, He, Kunyong, Yang, Tao, Jiang, Donald, Karanewsky, Xiang-ju, Gu, Vicki, Zhou, Yi, Liu, Jianwei, Che, Christian C, Lee, Jeremy, Caldwell, Takanori, Kanazawa, Ichiro, Umemura, Naoko, Matsuura, Osamu, Ohmori, Toshiyuki, Honda, Nathanael, Gray, Yun, He
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:2689-2692
A series of 2-amino-9-aryl-7H-pyrrolo[2,3-d]pyrimidines were designed and synthesized as focal adhesion kinase (FAK) inhibitors using molecular modeling in conjunction with a co-crystal structure. Chemistry was developed to introduce functionality on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be35e5a884056fb032ae480935f96970
https://doi.org/10.1016/j.bmcl.2006.02.032
https://doi.org/10.1016/j.bmcl.2006.02.032
Publikováno v:
ChemInform. 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23acb94717a361f960f9e604e13ba4e9
https://doi.org/10.1002/chin.199932230
https://doi.org/10.1002/chin.199932230
Autor:
Genji Iwasaki, Keiichi Masuya, Sachiyo Tada, Sandra W. Cowan-Jacob, Yuko Hitomi, Miyuki Horiuchi, Naoki Teno, Motohiko Kometani, Martin Missbach, Takeru Ehara, Keigo Gohda, Ichiro Umemura, Osamu Ohmori, Naoko Matsuura, Kazuhiko Nonomura, Takahiro Miyake, Osamu Irie, Hiroki Gunji, Claudia Betschart, Atsuko Iwasaki, Junichi Sakaki, Rene Lattmann
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(22)
Pyrrolopyrimidine, a novel scaffold, allows to adjust interactions within the S3 subsite of cathepsin K. The core intermediate 10 facilitated the P3 optimization and identified highly potent and selective cathepsin K inhibitors 11-20.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::294c9e7f93f4b97d4c94dbe37e9b8f8b
https://pubmed.ncbi.nlm.nih.gov/17911019
https://pubmed.ncbi.nlm.nih.gov/17911019
Autor:
Osamu Ohmori, Zhicheng Wang, Ha-Soon Choi, Yi Liu, Toshiyuki Honda, Jeremy S. Caldwell, Xiang-ju Gu, Wendy Richmond, Vicki Zhou, Takanori Kanazawa, Nathanael S. Gray, Kunyong Yang, Ichiro Umemura, Naoko Matsuura, Yun He, Donald S. Karanewsky, Tao Jiang, Christian C. Lee, Jianwei Che, Xiaohui He
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(8)
A series of 2-amino-9-aryl-7H-pyrrolo[2,3-d]pyrimidines were designed and synthesized to target focal adhesion kinase (FAK). A number of these pyrrolopyrimides exhibited low micromolar inhibitory activities against focal adhesion kinase, and their pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b2a9e17bc1cfd7311f5e69f0fb17cbf
https://pubmed.ncbi.nlm.nih.gov/16458503
https://pubmed.ncbi.nlm.nih.gov/16458503
Publikováno v:
HETEROCYCLES. 51:975
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e53dafcba6e0e3128e3db06b82d1318f
https://doi.org/10.3987/com-99-8499
https://doi.org/10.3987/com-99-8499
Autor:
Naoki Teno, Keiichi Masuya, Takeru Ehara, Takatoshi Kosaka, Takahiro Miyake, Osamu Irie, Yuko Hitomi, Naoko Matsuura, Ichiro Umemura, Genji Iwasaki, Hiroaki Fukaya, Kazuhiro Toriyama, Noriko Uchiyama, Kazuhiko Nonomura, Ikuo Sugiyama, Motohiko Kometani
Publikováno v:
Journal of Medicinal Chemistry; Jul2008, Vol. 51 Issue 17, p5459-5462, 4p
Publikováno v:
Surface and Coatings Technology. 30:191-198
Anodic oxidation of cobalt ferrous ferrites in ammonia-containing solutions proceeds by oxidation of iron and cobalt ions in the octahedral sites of the ferrites. Ammonia accelerates the oxidation of cobalt ions by forming ammine-aquo complexes at th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46156b8e81a25f5f464271084303ca77
https://doi.org/10.1016/0257-8972(87)90143-5
https://doi.org/10.1016/0257-8972(87)90143-5