Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Naoko Kawakami"'
Autor:
Caterina Riillo, Marco Rossi, Matthew Welsch, Tanya Berbasova, Lawrence Iben, Luca Rastelli, Pierfrancesco Tassone, Naoko Kawakami, Enrique Alvarez, Anna Bunin, David Spiegel, Takayuki Nagasawa, Ann Marie Rossi, Masaki Ohuchi
Publikováno v:
Blood. 134:4411-4411
Background: Antibody recruiting molecules (ARM) are novel, immunotherapeutic bifunctional molecules composed of two active termini connected by a linker. One of the termini binds to a target molecule on a cancer cell. The other terminus, called unive
Publikováno v:
Bioconjugate Chemistry. 19:65-69
We previously prepared the oligonucleotides (ODNs) conjugated to an anthraquinone (AQ) group via one carbon linker at the 2'-sugar position. When these modified ODNs bind to cDNA sequences, the AQ moiety can be intercalated into the predetermined bas
Autor:
Kimiko Miyagawa, Noshi Minamiura, Naoko Kawakami, Mutsumi Matsumoto, Shigeki Yabuno, Masaru Iizuka, Tasuku Hamaguchi, Kazuo Ito
Publikováno v:
Journal of Applied Glycoscience. 54:139-146
Endo-β-N-acetylglucosaminidases hydrolyze N,N´-diacetylchitobiose linkages of asparagine-linked oligosaccharides. They can also cleave the linkage with suitable agents having hydroxyl groups and transfer the released oligosaccharides to the agents.
Autor:
Manabu Nakano, Takamitsu Soma, Osamu Takikawa, Misato Hayashi, Atsushi Oda, Soichi Miwa, Lingyun Lu, Mitsuhiro Fukao, Tadashi Nishiya, Emi Kajita, Kazuhiko Nagai, Hiroyoshi Fujita, Naoko Kawakami
Publikováno v:
Archives of Biochemistry and Biophysics. 452(1):29-37
Acetylcarnitine exerts therapeutic effects on some neurological disorders including Alzheimer's disease. OCTN2 is known as a transporter for acetylcarnitine, but its expression in the brain is very low. To examine a brain-specific transporter for ace
Autor:
Yves Delneste, Tatsuya Sawamura, Jean-François Gauchat, Jean-François Haeuw, Pascale Jeannin, Jean-Yves Bonnefoy, Naoko Kawakami-Honda, Jean-Pierre Aubry, Kayo Nakamura, Giovanni Magistrelli, Liliane Goetsch
Publikováno v:
Immunity
Immunity, Elsevier, 2002, 17, pp.353-362
Immunity, Elsevier, 2002, 17, pp.353-362
International audience; Some exogenous antigens, such as heat shock proteins or apoptotic bodies, gain access to the MHC class I processing pathway and initiate CTL responses, a process called cross-priming. To be efficient in vivo, this process requ
Autor:
Naoko Kawakami, Shun Shimohama, Teruhide Yamaguchi, George Perry, Sadaki Fujimoto, Hiroomi Kodama, Akihiko Nunomura, Mark A. Smith, Takao Hayakawa, Naoki Okamura, Hiroko Tanino, Shigeru Chiba
Publikováno v:
Biochemical and Biophysical Research Communications. 273:5-9
The present study is the first to show that superoxide (O(-)(2)) forming NADPH oxidase is activated in Alzheimer's disease (AD) brains by demonstrating the marked translocation of the cytosolic factors p47-phox and p67-phox to the membrane. In conjun
Autor:
Shun Shimohama, Takao Hayakawa, Naoki Okamura, Hiroaki Takemasa, Naoko Kawakami, Sadaki Fujimoto
Publikováno v:
Biological and Pharmaceutical Bulletin. 22:556-560
Calyculin A, a protein phosphatase inhibitor, enhanced phorbol 12-myristate 13-acetate (PMA)-induced superoxide anion (O2-) production and translocation of the cytosolic NADPH oxidase factor, p47phox, to the plasma membrane in guinea pig polymorphonu
Publikováno v:
General Pharmacology: The Vascular System. 31:469-475
1. myo-Inositol monophosphatase (E.C. 3.1.3.25) hydrolyzes inositol monophosphate to form free myo-inositol, the precursor for the inositol phospholipid second-messenger signaling systems. The biochemical properties of the enzyme were examined in det
Autor:
Naoko Kawakami, Hiroshi Nakamura, Eiko Hibi, Yoshihiro Terazawa, Tomomi Watanabe-Kato, Takeshi Ikeda, Koji Nakayama, Toshihide Noguchi, C.I. Hoover, Fuminobu Yoshimura, Jun-ichiro Hayashi
Publikováno v:
Microbial Pathogenesis. 24:25-35
Fimbriae are considered to be an important virulence factor of Porphyromonas gingivalis. In order to identify genes essential for fimbriation, other than fimA which encodes the major subunit protein of fimbriae, transposon mutagenesis and immunologic
Autor:
Mikiko Kasugai-Sawada, Chikako Mitsuoka, Nozomu Hiraiwa, Makoto Kiso, Kenichi Toda, Naoko Kawakami-Kimura, Reiji Kannagi, Hideharu Ishida, Akira Hasegawa
Publikováno v:
Biochemical and Biophysical Research Communications. 230:546-551
Endothelial cells of high endothelial venules (HEV) in human peripheral lymph nodes expressed a distinct type of sialyl Lewis X antigen, which was detected preferentially with a set of anti-sialyl Lewis X antibodies, 2F3, 2H5 and HECA-452 in immunohi