Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Naoko Karino"'
Autor:
Mayumi Matsubara, Rei Hasegawa, Aya Masaoka, Hiroshi Ide, Hiroaki Terato, and Akira Matsuda, Yoshihiko Ohyama, Tamon Tanaka, Naoko Karino, Satofumi Kurisu
Publikováno v:
Biochemistry. 42:5003-5012
In the accompanying paper [Matsubara, M., et al. (2003) Biochemistry 42, 4993-5002], we have partially purified and characterized rat 5-formyluracil (fU)-DNA glycosylase (FDG). Several lines of evidence have indicated that FDG is a rat homologue of s
Publikováno v:
Biophysical Chemistry. 95:227-233
To investigate the role of divalent cations in crystal packing, a Dickerson-Drew-type dodecamer with the sequence d(CGCGAATXCGCG), containing 2'-deoxy-5-formyluridine at X, was crystallized under several conditions with Ba(2+) ion instead of Mg(2+) i
Autor:
Naoko Murata-Kamiya, Naoko Karino, Yoshihito Ueno, Akira Matsuda, Hiroyuki Kamiya, Hiroshi Kasai
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 513:213-222
Oxidatively damaged thymine, 5-formyluracil (5-fU), was incorporated into a predetermined site of double-stranded shuttle vectors. The nucleotide sequences in which the modified base was incorporated were 5'-CFTAAG-3' and 5'-CTFAAG-3' (F represents 5
Publikováno v:
Nucleic Acids Research. 29:2456-2463
Oligodeoxynucleotides (ODNs) containing 5-formyl-2′-deoxycytidine (fC) were synthesized by the phosphoramidite method and subsequent oxidation with sodium periodate. The stabilities of duplexes containing A, G, C or T opposite fC were studied by th
Autor:
Yoshihito Ueno, Naoko Murata-Kamiya, Akira Matsuda, Hiroyuki Kamiya, Hiroshi Kaji, Hiroshi Kasai, Naoko Karino
Publikováno v:
Nucleic Acids Research. 27:4385-4390
5-methyl-2'-deoxycytidine (5-Me-dC) is formed by the enzymatic methylation of dC, primarily in CpG sequences in DNA, and is involved in the regulation of gene expression. In the present study, 5-Me-dC and double-stranded DNA fragments containing 5-Me
Autor:
Akira Matsuda, Hiroyuki Kamiya, Naoko Karino, Naoko Murata-Kamiya, Yoshihito Ueno, Hiroshi Kasai
Publikováno v:
Nucleic acids symposium series. (44)
5-Formyluracil, a major oxidized form of thymine, was incorporated into a predetermined site of one of the leading and lagging template strands of a double-stranded vector, and the DNA replication efficiency and the mutation frequency of 5-formylurac
Autor:
Naoko Karino, Tomoko Sunami, Akio Takénaka, Akira Matsuda, T. Sakaue, Satoko Naito, Masaru Tsunoda, Yoshihito Ueno
Publikováno v:
Nucleic acids research. Supplement (2001). (1)
It is known that formylation of thymine base induces purine transition in DNA replication. In order to establish the structural basis for such mutagenesis, crystal structures of two kinds of DNA dodecamers d(CGCGRATf5UCGCG) with f5U = 2'-deoxy-5-form
Autor:
Yoshihito Ueno, Hideyoshi Harashima, Hiroyuki Tsuchiya, Naoko Karino, Akira Matsuda, Hiroyuki Kamiya
Publikováno v:
Journal of biochemistry. 132(4)
To examine the mutagenicity of 5-formylcytosine (5-fC), an oxidation product of 5-methylcytosine (5-mC), 5-fC was incorporated into predetermined sites of double-stranded shuttle vectors. The nucleotide sequences in which the modified base was incorp
Publikováno v:
Biochemistry. 41(29)
We have carried out an in vitro selection to obtain an allosteric hairpin ribozyme, which has cleavage activity in the presence of an exogenous short oligonucleotide as a regulator. Random sequences were inserted in a region corresponding to the hair
Publikováno v:
Bioconjugate chemistry. 11(6)
To construct the nuclease-resistant oligodeoxynucleotides (ODNs) with natural phosphodiester linkages, we synthesized ODNs that contain 6'alpha-[N-(aminoalkyl)carbamoyloxy]-carbocyclic-thymidines (4, 5, and 6). The stability of these ODNs to nuclease