Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Naoko Kakusho"'
Autor:
Sayuri Ito, Ai Ishii, Naoko Kakusho, Chika Taniyama, Satoshi Yamazaki, Rino Fukatsu, Asako Sakaue-Sawano, Atsushi Miyawaki, Hisao Masai
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36372 (2012)
BACKGROUND: Depletion of replication factors often causes cell death in cancer cells. Depletion of Cdc7, a kinase essential for initiation of DNA replication, induces cancer cell death regardless of its p53 status, but the precise pathways of cell de
Externí odkaz:
https://doaj.org/article/a56f2f0886fe4e928491b46f09122641
Publikováno v:
Biochemical and Biophysical Research Communications. 531:75-83
G-quadrupex is now known to play crucial roles in various biological reactions. However, direct evidence for its presence in cells has been limited, due to the lack of versatile and non-biased methodology. We use Rif1 binding sites on the fission yea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a31d36219c9096941140e296ec2ac77d
https://doi.org/10.1016/j.bbrc.2020.05.191
https://doi.org/10.1016/j.bbrc.2020.05.191
Publikováno v:
Journal of Biological Chemistry. 293:17033-17049
G-quadruplexes (G4s) are four-stranded DNA structures comprising stacks of four guanines, are prevalent in genomes, and have diverse biological functions in various chromosomal structures. A conserved protein, Rap1-interacting factor 1 (Rif1) from fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d98d6c778695136783017a1cbdba443
https://doi.org/10.1074/jbc.ra118.005240
https://doi.org/10.1074/jbc.ra118.005240
Autor:
Kazuo Nagasawa, Yutaka Kanoh, Naoko Kakusho, Yue Ma, Kenji Moriyama, Hisao Masai, Rino Fukatsu, Keisuke Iida
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Rif1 is a conserved protein regulating replication timing and binds preferentially to the vicinity of late-firing/dormant origins in fission yeast. The Rif1 binding sites on the fission yeast genome have an intrinsic potential to generate G-quadruple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b59d1fb5671b396ad45b94fe196a86
https://doi.org/10.1038/s41598-019-44736-9
https://doi.org/10.1038/s41598-019-44736-9
Autor:
Naoko Kakusho, Seiji Matsumoto, Rino Fukatsu, Yutaka Kanoh, Shigeru Chaen, Hisao Masai, Shunsuke Kobayashi
Publikováno v:
Molecular and Cellular Biology
Rif1 is a key factor for spatiotemporal regulation of DNA replication. Rif1 suppresses origin firing in the mid-late replication domains by generating replication-suppressive chromatin architecture and by recruiting a protein phosphatase.
Rif1 i
Rif1 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe594ae66dcd0bda657d021a4a4e478
https://doi.org/10.1128/mcb.00364-18
https://doi.org/10.1128/mcb.00364-18
Autor:
Pierre Thibault, Zhiying You, Alain Verreault, Marlene Gharib, Krassimir Yankulov, Hisao Masai, Naoko Kakusho, Erin Drury, Daniel Jeffery, Brandon A. Wyse, Michael Weinreich
Publikováno v:
Cell Cycle. 14:74-85
Chromatin Assembly Factor I (CAF-I) plays a key role in the replication-coupled assembly of nucleosomes. It is expected that its function is linked to the regulation of the cell cycle, but little detail is available. Current models suggest that CAF-I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c7a10a6b2cf9e29de4d09de2d1aa4d
https://doi.org/10.4161/15384101.2014.973745
https://doi.org/10.4161/15384101.2014.973745
Autor:
Seiji Matsumoto, Michie Shimmoto, Naoko Kakusho, Hisao Masai, Rino Fukatsu, Motoshi Hayano, Kyosuke Ueda, Yutaka Kanoh
Publikováno v:
Molecular and Cellular Biology. 37
Mrc1 is a conserved checkpoint mediator protein that transduces the replication stress signal to the downstream effector kinase. The loss of mrc1 checkpoint activity results in the aberrant activation of late/dormant origins in the presence of hydrox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f3ee5a0adaa9a09ea3cce8a7fe0f390
https://doi.org/10.1128/mcb.00355-16
https://doi.org/10.1128/mcb.00355-16
Autor:
Naoko Kakusho, Gaik-theng Toh, Rino Fukatsu, Ho-Jin Chang, Satoshi Yamazaki, Hisao Masai, Kazuo Yanagi, Ryo Kitamura, Chika Taniyama, Naoko Arai, Yong-Soon Cho
Publikováno v:
Journal of Biological Chemistry. 286:23031-23043
Cdc7 is a serine/threonine kinase conserved from yeasts to human and is known to play a key role in the regulation of initiation at each replication origin. Its catalytic function is activated via association with the activation subunit Dbf4/activato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2e4c3e9e9dea37ae04ba5612671b448
https://doi.org/10.1074/jbc.m111.243311
https://doi.org/10.1074/jbc.m111.243311
Autor:
Yutaka Kanoh, Motoshi Hayano, Naoko Kakusho, Mika Yokoyama, Hisao Masai, Paul Russell, Seiji Matsumoto, Michie Shimmoto
Publikováno v:
Cell Cycle. 9:4627-4637
In fission yeast, replication fork arrest activates the replication checkpoint effector kinase Cds1Chk2/Rad53 through the Rad3ATR/Mec1-Mrc1Claspin pathway. Hsk1, the Cdc7 homolog of fission yeast required for efficient initiation of DNA replication,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16b3d08b688ae2767c06a1334129f2a5
https://doi.org/10.4161/cc.9.23.13937
https://doi.org/10.4161/cc.9.23.13937
Autor:
Lena R. Kundu, Takemi Enomoto, Shusuke Tada, Yuji Kumata, Asako Furukohri, Naoko Kakusho, Saori Watanabe, Masayuki Seki, Hisao Masai, Shou Waga
Publikováno v:
Nucleic Acids Research
Mcm2–7 is recruited to eukaryotic origins of DNA replication by origin recognition complex, Cdc6 and Cdt1 thereby licensing the origins. Cdc6 is essential for origin licensing during DNA replication and is readily destabilized from chromatin after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5553d035eb86d3d71c6f1b74ec0f6ac4
http://europepmc.org/articles/PMC2938227
http://europepmc.org/articles/PMC2938227