Zobrazeno 1 - 10 of 16 pro vyhledávání: '"Naoko Irako"'
1
An Efficient Synthesis of Sulfobacin A (Flavocristamide B), Sulfobacin B, and Flavocristamide A
Autor: Takayuki Shioiri, Naoko Irako
Publikováno v: Tetrahedron. 56:9129-9142
Sulfobacin A (flavocristamide B, 1), sulfobacin B (2), and flavocristamide A (3), biologically active sulfonolipids, have been efficiently synthesized utilizing the asymmetric aldol reaction of the Schiff base 8 derived from glycine ester and (+)-2-h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aa35f122dd41319728d7c292d6a1e6f0
https://doi.org/10.1016/s0040-4020(00)00768-7
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2
Synthesis of topostins B567 and D654 (WB-3559D, flavolipin), DNA topoisomerase I inhibitors of bacterial origin
Autor: Yoshihiro Terao, Toyohiko Aoyama, Takayuki Shioiri, Naoko Irako
Publikováno v: Tetrahedron. 54:15701-15710
Topostins B567 (2b) and D654 (3b) (WB-3559D, flavolipin) have been efficiently synthesized from 1, 10-decanediol (5) in 11 and 13 steps, respectively, involving an asymmetric hydrogenation of the β-keto ester14 using(R)-BINAP ruthenium bromide and a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e65fe37f8ecf230fcf504b521685f1d0
https://doi.org/10.1016/s0040-4020(98)00984-3
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3
Total synthesis of sulfobacin A (flavocristamide B)
Autor: Takayuki Shioiri, Naoko Irako
Publikováno v: Tetrahedron Letters. 39:5793-5796
Sulfobacin A (1), a novel von Willcbrand factor receptor antagonist isolated from the culture broth of Chryseobacterium sp. NR 2993, was efficiently synthesized for the first time.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::68ccd87b3c95e96ddc8e481701dab03c
https://doi.org/10.1016/s0040-4039(98)01177-0
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4
A New Asymmetric Synthesis of (S)-Dolaphenine and Its Heteroaromatic Congeners Utilizing (+)-2-Hydroxy-3-pinanone and (−)-3-Hydroxy-2-caranone as Chiral Auxiliaries
Autor: Yasumasa Hamada, Naoko Irako, Takayuki Shioiri
Publikováno v: Tetrahedron. 51:12731-12744
(+)-2-Hydroxy-3-pinanone ((+)-HyPN, (+)-2a) and (−)-3-hydroxy-2-caranone ((−) 2b) were respectively converted to the corresponding Schiff bases 18a and 18b with 1-(2 thiazolyl)methylamine (17). Alkylation followed by removal of the chiral auxilia
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d68acc7999c221b238478097eecfd83
https://doi.org/10.1016/0040-4020(95)00828-v
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5
ChemInform Abstract: A New Asymmetric Synthesis of (S)-Dolaphenine and Its Heteroaromatic Congeners Utilizing (+)-2-Hydroxy-3-pinanone and (-)-3-Hydroxy-2- caranone as Chiral Auxiliaries
Autor: Naoko Irako, Takayuki Shioiri, Yasumasa Hamada
Publikováno v: ChemInform. 27
(+)-2-Hydroxy-3-pinanone ((+)-HyPN, (+)-2a) and (−)-3-hydroxy-2-caranone ((−) 2b) were respectively converted to the corresponding Schiff bases 18a and 18b with 1-(2 thiazolyl)methylamine (17). Alkylation followed by removal of the chiral auxilia
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cba06a81bc1e34b7f825cb9040a8f545
https://doi.org/10.1002/chin.199611245
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7
ChemInform Abstract: Total Synthesis of Sulfobacin A (Flavocristamide B)
Autor: Naoko Irako, Takayuki Shioiri
Publikováno v: ChemInform. 29
Sulfobacin A (1), a novel von Willcbrand factor receptor antagonist isolated from the culture broth of Chryseobacterium sp. NR 2993, was efficiently synthesized for the first time.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cbf0351be74529d099ba383e1da890ff
https://doi.org/10.1002/chin.199843274
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8
ChemInform Abstract: Synthesis of Topostins B567 and D654 (WB-3559D, Flavolipin), DNA Topoisomerase I Inhibitors of Bacterial Origin
Autor: Naoko Irako, Yoshihiro Terao, Toyohiko Aoyama, Takayuki Shioiri
Publikováno v: ChemInform. 30
Topostins B567 (2b) and D654 (3b) (WB-3559D, flavolipin) have been efficiently synthesized from 1, 10-decanediol (5) in 11 and 13 steps, respectively, involving an asymmetric hydrogenation of the β-keto ester14 using(R)-BINAP ruthenium bromide and a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::58976e441a8caf9950261a79029cb047
https://doi.org/10.1002/chin.199918223
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10
A new efficient synthesis of (S)-dolaphenine ((S)-2-phenyl-1-(2-thiazolyl)ethylamine), the C-terminal unit of dolastatin 10
Autor: Naoko Irako, Yasumasa Hamada, Takayuki Shioiri
Publikováno v: Tetrahedron. 48:7251-7264
Four methods for the preparation of (S)-dolaphenine ((S)-2-phenyl-1-(2-thiazolyl)ethylamine, 2), which constitutes the C-termina unit of dolastatin 10 (1) having strong anticancer activity, has been investigated. Of these, the most efficient one invo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de3ea9f732435204ce7f3e5906eda800
https://doi.org/10.1016/s0040-4020(01)88264-8
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