Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Naoko Higashijima"'
Autor:
Shun Horaguchi, Yoshiro Nakahara, Yuka Igarashi, Taku Kouro, Feifei Wei, Kenta Murotani, Seiichi Udagawa, Naoko Higashijima, Norikazu Matsuo, Shuji Murakami, Terufumi Kato, Tetsuro Kondo, Huihui Xiang, Rika Kasajima, Hidetomo Himuro, Kayoko Tsuji, Yasunobu Mano, Mitsuru Komahashi, Yohei Miyagi, Haruhiro Saito, Koichi Azuma, Shuichiro Uehara, Tetsuro Sasada
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1831 (2024)
Neutrophil extracellular traps (NETs) released from neutrophils are related to cancer progression. However, the relationship between the therapeutic effects of immune checkpoint inhibitors (ICIs) such as anti-PD-1 and anti-PD-L1 antibodies and plasma
Externí odkaz:
https://doaj.org/article/4b39897048e4485b88664befbd1be51d
Autor:
Yoshiro Nakahara, Taku Kouro, Satoru Motoyama, Masatomo Miura, Kazuma Fujita, Yuka Igarashi, Naoko Higashijima, Norikazu Matsuo, Hidetomo Himuro, Feifei Wei, Shun Horaguchi, Kayoko Tsuji, Yasunobu Mano, Mitsuru Komahashi, Haruhiro Saito, Koichi Azuma, Tetsuro Sasada
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Introduction: Clinical roles of plasma IL-6 levels have been reported in patients with various cancers, including non-small cell lung cancer (NSCLC), treated with immune checkpoint inhibitors (ICIs). However, the roles of other IL-6 signaling compone
Externí odkaz:
https://doaj.org/article/c99406045248454083cba711ad18ebf5
Autor:
Ken Aizawa, Youko Takahari, Naoko Higashijima, Kenichi Serizawa, Kenji Yogo, Nobuhiko Ishizuka, Koichi Endo, Naoto Fukuyama, Katsuya Hirano, Hideyuki Ishida
Publikováno v:
Journal of Pharmacological Sciences, Vol 127, Iss 3, Pp 284-291 (2015)
Sirolimus (SRL) is widely used to prevent restenosis after percutaneous coronary intervention. However, its beneficial effect is hampered by complications of thrombosis. Several studies imply that reactive oxygen species (ROS) play a critical role in
Externí odkaz:
https://doaj.org/article/01879e53d2854fec8cd3a5c71ae56ccc
Autor:
Hidetomo Himuro, Yoshiro Nakahara, Yuka Igarashi, Taku Kouro, Naoko Higashijima, Norikazu Matsuo, Shuji Murakami, Feifei Wei, Shun Horaguchi, Kayoko Tsuji, Yasunobu Mano, Haruhiro Saito, Koichi Azuma, Tetsuro Sasada
Publikováno v:
Cancer Immunology, Immunotherapy.
Introduction Immune checkpoint inhibitors (ICI) have significantly improved the prognosis of non-small cell lung cancer (NSCLC). However, only a limited proportion of patients can benefit from this therapy, and clinically useful predictive biomarkers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c321377dcd9c3e0e6a11b6b4d157ca35
https://doi.org/10.1007/s00262-023-03464-w
https://doi.org/10.1007/s00262-023-03464-w
Autor:
Yagnesh Tailor, Kelley S. Yan, Moritz Middelhoff, Sozaburo Ihara, Yoku Hayakawa, Yoshihiro Hirata, Yohko Hikiba, Woosook Kim, Yukiko Oya, Chandan Guha, Naoko Higashijima, Tetsuo Ushiku, Samuel Asfaha, Kazuhiko Koike, Masashi Fukayama, Hiroto Kinoshita, Mayo Tsuboi, Mitsuru Konishi, Masahiro Hata, Timothy C. Wang, Ryota Niikura
Publikováno v:
Paediatrics Publications
Background & Aims The intestinal epithelium is maintained by long-lived intestinal stem cells (ISCs) that reside near the crypt base. Above the ISC zone, there are short-lived progenitors that normally give rise to lineage-specific differentiated cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00bbe0fdad1108d1b20121cd6fe727b4
https://europepmc.org/articles/PMC6409180/
https://europepmc.org/articles/PMC6409180/
Autor:
Nobuhiko Ishizuka, Kenji Yogo, Naoto Fukuyama, Kenichi Serizawa, Ken Aizawa, Naoko Higashijima, Koichi Endo, Hideyuki Ishida, Katsuya Hirano, Youko Takahari
Publikováno v:
Journal of Pharmacological Sciences, Vol 127, Iss 3, Pp 284-291 (2015)
Sirolimus (SRL) is widely used to prevent restenosis after percutaneous coronary intervention. However, its beneficial effect is hampered by complications of thrombosis. Several studies imply that reactive oxygen species (ROS) play a critical role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6f27cc04a039784eb95ca94999e72b
http://www.sciencedirect.com/science/article/pii/S1347861315000341
http://www.sciencedirect.com/science/article/pii/S1347861315000341
Autor:
Youko Takahari, Naoko Higashijima, Noriko Tamura, Yota Kawamura, Nobuhiko Ishizuka, Hideyuki Ishida, Yu Eguchi
Publikováno v:
Circulation Journal. 73:554-561
Background: Although nicorandil has a number of beneficial cardiovascular actions, its effects on endothelial cells in the context of thrombosis have not been elucidated. Methods and Results: Arterial thrombosis was induced by endothelial injury caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64463513fe23ca7af5971c736142f29
https://doi.org/10.1253/circj.cj-08-0843
https://doi.org/10.1253/circj.cj-08-0843
Autor:
Minako Hoshiai, Hiroe Nakazawa, Yu Eguchi, Naoko Higashijima, Shinpei Nakazawa, Hideyuki Ishida, Takako Toda, Toshie Kadono
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 293:H3517-H3523
The Na+/H+ exchanger (NHE) inhibitor cariporide has a cardioprotective effect in various animal models of myocardial ischemia-reperfusion. Recent studies have suggested that cariporide interacts with mitochondrial Ca2+ overload and the mitochondrial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a98f82d78af5a52044085cceb74c5d
https://doi.org/10.1152/ajpheart.00483.2006
https://doi.org/10.1152/ajpheart.00483.2006
Autor:
Yuki Hirota, Haruaki Nakaya, Hiroe Nakazawa, Hideyuki Ishida, Toshiaki Sato, Chokoh Genka, Naoko Higashijima
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 369:192-197
The anti-anginal drug nicorandil has been demonstrated to protect the myocardium against ischemic injury in both experimental and clinical studies. Although nicorandil seems to protect the myocardium via activation of mitochondrial ATP-sensitive K+ (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d49e21245928102dddeb845a02c27db
https://doi.org/10.1007/s00210-003-0851-z
https://doi.org/10.1007/s00210-003-0851-z
Autor:
Takuya Ikeda, Naoko Higashijima
Publikováno v:
JOURNAL OF PAVEMENT ENGINEERING, JSCE. 3:9-14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aacce7aa2b45855d9e6d4785455e0da5
https://doi.org/10.2208/journalpe.3.9
https://doi.org/10.2208/journalpe.3.9