Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Naoko Funeshima"'
Autor:
Masayuki Fujino, Xiao-Kang Li M.D., Ph.D., Yusuke Kitazawa, Naoko Funeshima, Lei Guo, Torayuki Okuyama, Takashi Amano, Hiroshi Amemiya, Seiichi Suzuki
Publikováno v:
Cell Transplantation, Vol 10 (2001)
Hepatocyte transplantation has been proposed as a potential therapeutic method to treat irreversible liver failure and inherited hepatic disorders, although transplanted cells do not easily reconstruct the liver tissue under intact conditions. This s
Externí odkaz:
https://doaj.org/article/b4aeb4a121c9413a87d8970688b86444
Autor:
Masao Yamada, Seiichi Suzuki, Motomichi Kosuga, Hidetsugu Saito, Torayuki Okuyama, Xiao-Kang Li, Naoko Funeshima, Kyoko Sasaki, Masahiko Takahashi, Masayuki Fujino, Yusuke Kita
Publikováno v:
Journal of gastroenterology and hepatology. 13(S1)
Gene-transduced hepatocytes with E1/E3-deleted adenoviral vectors are eliminated immediately and the expression of transduced genes disappears rapidly following the vector administration. In this report, we analysed the involvement of apoptotic cell
Autor:
Xiao-Kang Li, Yoh Matsumoto, Shiro Takahara, Yoshitaka Isaka, Lin Xie, Hiromitsu Kimura, Naoko Funeshima-Fuji
Publikováno v:
International Immunopharmacology. 9:575-581
Experimental autoimmune encephalomylitis (EAE), an animal mode of multiple sclerosis (MS), was previously considered that be mediated by Th1 cells. However, a number of recent studies provided strong evidence that T helper cells that produce IL-17 pl
Autor:
Toshinori Nakayama, Xiao-Kang Li, Masayuki Fujino, Naoko Funeshima-Fuji, Taichi Ezaki, Shiro Takahara, Hiromitsu Kimura
Publikováno v:
Transplant Immunology. 18:302-306
Ras is a guanine nucleotide-binding protein that plays a major role in regulating the proliferation of T cells. To investigate the mechanism of the Ras/mitogen-activated protein kinase pathway, one of the downstream signal-transduction pathways of T-
Autor:
Xiao-Kang Li, Tohko Miyagi, Yuhko Hara, Lei Guo, Kenichi Teramoto, Takashi Satoh, Yuhsuke Kitazawa, Naoki Yamamoto, Wataru Sugiura, Keiichi Ogata, E. Satoh, Naoko Funeshima-Fuji, Hiromitsu Kimura, Shigeki Arii
Publikováno v:
Transplant Immunology. 18:73-84
Enhanced green fluorescence protein (EGFP) has been widely applied to gene transduction in cellular and molecular biology as a reporter element. When applied to cell transplantation, it raises fundamental issues concerning cell-associated antigens, i
Autor:
Yoshinobu Sato, Hiromitsu Kimura, Xiao-Kang Li, Naoko Funeshima, Mikiko Kawasaki, Yoshiaki Hara, Yusuke Kitazawa, Katsunari Tezuka, Katsuyoshi Hatakeyama
Publikováno v:
International Immunopharmacology. 6:1143-1151
Regulatory cells may play a pivotal role in inducing and maintaining transplantation tolerance. We investigated the mechanism of anergic lymphocytes with regulatory cell potential generated in vitro by ICOS and CD 28 co-stimulatory blockades as a sou
Publikováno v:
Surgery Today. 36:367-375
We used recombinant adenoviral vectors for gene therapy in liver transplantation, and investigated the efficacy of gene transfer and expression on the grafts and genetic heterogeneity, with two exogenous gene transfer methods in three different synge
Autor:
Chieko Kuwae, Masami Kanayama, Naoko Funeshima, Xiao-Kang Li, Terumi Takahara, Yusuke Kitazawa, Kazunobu Nonome, Shigeru Saito, Toshiro Sugiyama, Eiji Shinno, Feng Xue, Akiharu Watanabe, Yutaka Yata
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 289:G1091-G1099
Human umbilical cord blood (HUCB) contains stem/progenitor cells, which can differentiate into a variety of cell types. In this study, we investigated whether HUCB cells differentiate into hepatocytes in vitro and in vivo. We also examined whether CD
Characterization and gene transfer in mesenchymal stem cells derived from human umbilical-cord blood
Autor:
Jian-Yuan Jiang, Naoko Funeshima, Akihiro Umezawa, Masayuki Fujino, Fei-Zhou Lu, Taro Uyama, Xiao-Kang Li, Yusuke Kitazawa, Yuko Hara
Publikováno v:
Journal of Laboratory and Clinical Medicine. 146:271-278
It has been shown that the stromal-cell population found in bone marrow can be expanded and differentiated into cells with the phenotypes of bone, cartilage, muscle, neural, and fat cells. However, whether mesenchymal stem cells (MSCs) are present in
Autor:
Toshiharu Nakajima, Masayuki Fujino, Mikiko Kawasaki, Xiao-Kang Li, Yusuke Kitazawa, Naoko Funeshima, Hiromitsu Kimura, Hirohisa Saito
Publikováno v:
Liver Transplantation. 10:379-391
Induction of tolerance to allogeneic donor grafts is a clinically desirable goal in bone marrow and solid organ transplantation. We have taken the advantage of DNA microarray technology to investigate gene expression mechanism in regulatory cells. In