Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Naoko Kanatani"'
Autor:
Shin-ichi Izumi, Hisato Komori, Kunio Takaoka, Takafumi Maeno, Takeshi Moriishi, Carolina A. Yoshida, Toshihisa Komori, Naoko Kanatani
Publikováno v:
Bone. 49:673-682
RUNX2 is an essential transcription factor for osteoblast differentiation, because osteoblast differentiation is completely blocked in Runx2-deficient mice. However, it remains to be clarified whether RUNX2 is sufficient for osteoblast differentiatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ede5f9df5137c185695aa2abe461b0a
https://doi.org/10.1016/j.bone.2011.07.023
https://doi.org/10.1016/j.bone.2011.07.023
Autor:
Hisato Komori, Takashi Fujita, Satoshi Rokutanda, Wenguang Liu, Akio Mizuno, Naoko Kanatani, Carolina A. Yoshida, Toshihisa Komori
Publikováno v:
Developmental Biology. 328(1):78-93
Although Akt plays key roles in various cellular processes, the functions of Akt and Akt downstream signaling pathways in the cellular processes of skeletal development remain to be clarified. By analyzing transgenic embryos that expressed constituti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9189866cffd4c582a279df141e774300
https://nagasaki-u.repo.nii.ac.jp/records/17509
https://nagasaki-u.repo.nii.ac.jp/records/17509
Autor:
Shinji Takada, Carolina A. Yoshida, Reiko Nakamura, Satoru Toyosawa, Naoko Kanatani, Toshihisa Komori, Toshihiro Miyazaki, Satoshi Rokutanda
Publikováno v:
Archives of Histology and Cytology. 71:131-146
Runx2 is an essential transcription factor for bone and tooth development whose function in odontoblast differentiation remains to be clarified. To pursue this issue, we examined tooth development in Runx2 transgenic mice under the control of Col1a1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e24d164a4b192806905eef3b564746a1
https://doi.org/10.1679/aohc.71.131
https://doi.org/10.1679/aohc.71.131
Autor:
Kei Yamana, Toshihiro Miyazaki, Kozo Nakamura, Ryo Fukuyama, Toshihisa Komori, Norio Amizuka, Takeshi Moriishi, Masako Ito, Tatsuya Furuichi, Zenjiro Maruyama, Hiroshi Kawaguchi, Hideki Kitaura, Naoko Kanatani, Carolina A. Yoshida, Kouhei Nakamura, Takashi Fujita, Wenguang Liu
Publikováno v:
Developmental Dynamics. 236:1876-1890
Runx2 is an essential transcription factor for osteoblast differentiation. However, the functions of Runx2 in postnatal bone development remain to be clarified. Introduction of dominant-negative (dn)-Runx2 did not inhibit Col1a1 and osteocalcin expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf98925595cbaa32d210ee5f2751fef8
https://doi.org/10.1002/dvdy.21187
https://doi.org/10.1002/dvdy.21187
Autor:
Eiki Koyama, Toshihisa Komori, Yoshihiko Yamada, Jirota Kitagaki, Maurizio Pacifici, Yoshihiro Tamamura, Satoshi Wakisaka, Tomohiro Otani, Frank Costantini, Motomi Enomoto-Iwamoto, Naoko Kanatani, Masahiro Iwamoto
Publikováno v:
Journal of Biological Chemistry. 280:19185-19195
Studies have suggested that continuous Wnt/beta-catenin signaling in nascent cartilaginous skeletal elements blocks chondrocyte hypertrophy and endochondral ossification, whereas signaling starting at later stages stimulates hypertrophy and ossificat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef707b0f6229eb5a84441b11661fc5f
https://doi.org/10.1074/jbc.m414275200
https://doi.org/10.1074/jbc.m414275200
Autor:
Mitsuhiko Kobata, Mitsunobu Kishino, Naokuni Ijuhin, Satoru Toyosawa, Toshihisa Komori, Naoko Kanatani, Seikou Shintani, Michiko Yuki
Publikováno v:
Bone. 35:553-561
Dentin matrix protein 1 (DMP1) is one of the acidic phosphorylated extracellular matrix proteins called the SIBLING (small integrin-binding ligand, N-linked glycoproteins) family. Recent studies showed that DMP1 is expressed in the mineralized tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b9ae5c7a61ee14147248ab95c2ee56
https://doi.org/10.1016/j.bone.2004.03.030
https://doi.org/10.1016/j.bone.2004.03.030
Autor:
Kenji Takada, Naoko Kanatani, Toshihisa Komori, Tatsuya Furuichi, Ryo Fukuyama, Masanobu Satake, Shinji Kobayashi, Carolina A. Yoshida, Takashi Fujita
Publikováno v:
Nature Genetics. 32:633-638
Core-binding factor beta (CBFbeta, also called polyomavirus enhancer binding protein 2beta (PEBP2B)) is associated with an inversion of chromosome 16 and is associated with acute myeloid leukemia in humans. CBFbeta forms a heterodimer with RUNX1 (run
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c9d578cb69e24fcc218b98f5ef9cfa
https://doi.org/10.1038/ng1015
https://doi.org/10.1038/ng1015
Autor:
Philippa Francis-West, Tsutomu Nohno, Kojiro Kurisu, Motomi Enomoto-Iwamoto, Jirouta Kitagaki, Maurizio Pacifici, Eiki Koyama, Toshiyuki Yoneda, Toshihisa Komori, Yoshihiro Tamamura, Naoko Kanatani, Masahiro Iwamoto, Changshan Wu, Vicki Church, Tatsuya Koike, Hiroshi Okada
Publikováno v:
Developmental Biology. 251:142-156
The Wnt antagonist Frzb-1 is expressed during limb skeletogenesis, but its roles in this complex multistep process are not fully understood. To address this issue, we determined Frzb-1 gene expression patterns during chick long bone development and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e4c9f50f4ce7cc06059309db9a9bcdc
https://doi.org/10.1006/dbio.2002.0802
https://doi.org/10.1006/dbio.2002.0802
Autor:
Ryo Fukuyama, Takeshi Moriishi, Naoko Kanatani, Takashi Fujita, Wenguang Liu, Satoru Toyosawa, Toshihisa Komori, Toshihiro Miyazaki, Carolina A. Yoshida, Kei Yamana
Publikováno v:
Developmental biology. 296(1)
Runx2 and Cbfbeta are essential for skeletal development during the embryonic stage. Runx2 has two isoforms with different N-termini. We examined the functions of the Runx2 isoforms and Cbfbeta in postnatal bone development. On luciferase and electro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9288de8d295e36ba4a09167aecaf4912
https://pubmed.ncbi.nlm.nih.gov/16797526
https://pubmed.ncbi.nlm.nih.gov/16797526
Autor:
Naoko Kanatani, Tatsuya Furuichi, Ryo Fukuyama, Kanji Higashio, Hirayuki Enomoto, Kazuki Yano, Carolina A. Yoshida, Satoko Shiojiri, Kenji Takada, Toshihisa Komori, Kazuto Hoshi, Akira Zanma, Atsuko Mizuno, Reiko Nakamura, Hisataka Yasuda
Publikováno v:
The Journal of biological chemistry. 278(26)
Receptor activator of nuclear factor-kappaB ligand (RANKL), osteoprotegerin (OPG), and macrophage-colony stimulating factor play essential roles in the regulation of osteoclastogenesis. Runx2-deficient (Runx2-/-) mice showed a complete lack of bone f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2600d7eb5ef91b8ba1e7cfa80d739f90
https://pubmed.ncbi.nlm.nih.gov/12697767
https://pubmed.ncbi.nlm.nih.gov/12697767