Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Naoko, Nose"'
Autor:
Anna Janz, Katharina Walz, Alexandra Cirnu, Jessica Surjanto, Daniela Urlaub, Miriam Leskien, Michael Kohlhaas, Alexander Nickel, Theresa Brand, Naoko Nose, Philipp Wörsdörfer, Nicole Wagner, Takahiro Higuchi, Christoph Maack, Jan Dudek, Kristina Lorenz, Eva Klopocki, Süleyman Ergün, Henry J. Duff, Brenda Gerull
Publikováno v:
Molecular Metabolism, Vol 79, Iss , Pp 101859- (2024)
Background: Dilated cardiomyopathy with ataxia (DCMA) is an autosomal recessive disorder arising from truncating mutations in DNAJC19, which encodes an inner mitochondrial membrane protein. Clinical features include an early onset, often life-threate
Externí odkaz:
https://doaj.org/article/6548eb7053f84f48be1c05ed1eeff5e5
Autor:
Yukihiro Saito, Naoko Nose, Toshihiro Iida, Kaoru Akazawa, Takayuki Kanno, Yuki Fujimoto, Takanori Sasaki, Masaru Akehi, Takahiro Higuchi, Satoshi Akagi, Masashi Yoshida, Toru Miyoshi, Hiroshi Ito, Kazufumi Nakamura
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionTransplantation of human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) is a promising treatment for heart failure. Information on long-term cell engraftment after transplantation is clinically important. However, clinica
Externí odkaz:
https://doaj.org/article/4b50470f16fc41e0995e29db4a77eded
Autor:
Rudolf A. Werner, Takahiro Higuchi, Naoko Nose, Fujio Toriumi, Yohji Matsusaka, Ichiei Kuji, Koshino Kazuhiro
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Deep convolutional generative adversarial networks (GAN) allow for creating images from existing databases. We applied a modified light-weight GAN (FastGAN) algorithm to cerebral blood flow SPECTs and aimed to evaluate whether this technolog
Externí odkaz:
https://doaj.org/article/2176e9748ae3470fa27440af20635fb1
Autor:
Naoko Nose, Suguru Nogami, Kazuhiro Koshino, Xinyu Chen, Rudolf A. Werner, Soki Kashima, Steven P. Rowe, Constantin Lapa, Kazuki Fukuchi, Takahiro Higuchi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Stem cell therapy holds great promise for tissue regeneration and cancer treatment, although its efficacy is still inconclusive and requires further understanding and optimization of the procedures. Non-invasive cell tracking can provide an
Externí odkaz:
https://doaj.org/article/9212afd2f67542e299355bc54cce9b67
Autor:
Yohji Matsusaka, Rudolf A. Werner, Paula Arias-Loza, Naoko Nose, Takanori Sasaki, Xinyu Chen, Constantin Lapa, Takahiro Higuchi
Publikováno v:
Molecular Imaging, Vol 2022 (2022)
Background. Equipped with two stationary detectors, a large bore collimator for medium-sized animals has been recently introduced for dedicated preclinical single-photon emission computed tomography (SPECT) imaging. We aimed to evaluate the basic per
Externí odkaz:
https://doaj.org/article/68d64dd31b1749bb8f6b9c2510692477
In Vivo Functional Assessment of Sodium-Glucose Cotransporters (SGLTs) Using [18F]Me4FDG PET in Rats
Autor:
Yohji Matsusaka, Xinyu Chen, Paula Arias-Loza, Rudolf A. Werner, Naoko Nose, Takanori Sasaki, Steven P. Rowe, Martin G. Pomper, Constantin Lapa, Takahiro Higuchi
Publikováno v:
Molecular Imaging, Vol 2022 (2022)
Background. Mediating glucose absorption in the small intestine and renal clearance, sodium glucose cotransporters (SGLTs) have emerged as an attractive therapeutic target in diabetic patients. A substantial fraction of patients, however, only achiev
Externí odkaz:
https://doaj.org/article/c2c11cc014ca48c7bd88def15bc8c258
Autor:
Anna Tutov, Xinyu Chen, Rudolf A. Werner, Saskia Mühlig, Thomas Zimmermann, Naoko Nose, Kazuhiro Koshino, Constantin Lapa, Michael Decker, Takahiro Higuchi
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 690 (2023)
Purpose: A new PET radiotracer 18F-AF78 showing great potential for clinical application has been reported recently. It belongs to a new generation of phenethylguanidine-based norepinephrine transporter (NET)-targeting radiotracers. Although many eff
Externí odkaz:
https://doaj.org/article/292ce66f3971432f894c9a222e721fbe
Autor:
Christoph Eissler, Rudolf A. Werner, Paula Arias-Loza, Naoko Nose, Xinyu Chen, Martin G. Pomper, Steven P. Rowe, Constantin Lapa, Andreas K. Buck, Takahiro Higuchi
Publikováno v:
Molecular Imaging, Vol 2021 (2021)
Objectives. This study is aimed at investigating the impact of frame numbers in preclinical electrocardiogram- (ECG-) gated 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) on systolic and diastolic left ventricular (LV) parameters
Externí odkaz:
https://doaj.org/article/2f691629a5bf474193864968227113b4
Autor:
Xinyu Chen, Rudolf A. Werner, Constantin Lapa, Naoko Nose, Mitsuru Hirano, Mehrbod S. Javadi, Simon Robinson, Takahiro Higuchi
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-8 (2018)
Abstract Background 18F-N-[3-bromo-4-(3-fluoro-propoxy)-benzyl]-guanidine (18F-LMI1195) is a new class of PET tracer designed for sympathetic nervous imaging of the heart. The favorable image quality with high and specific neural uptake has been prev
Externí odkaz:
https://doaj.org/article/22f3970ba3434e7d8325fdc6752a15d6
Autor:
Natsumi Ikeno, Takahiro Nishi, Kenta Itahashi, Naoko Nose-Togawa, Akari Tani, Satoru Hirenzaki
Publikováno v:
Progress of Theoretical and Experimental Physics. 2023
We investigate the possibility of determining the value of the pion–nucleon sigma term σπN precisely by the experimental observables of deeply bound pionic atoms. We discuss the sensitivity of the observables to σπN and take into account the ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf6d2d58a0022183528d63449c68962b
https://doi.org/10.1093/ptep/ptad031
https://doi.org/10.1093/ptep/ptad031