Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Naoko, Ichiishi"'
Autor:
Andrew V. Mossine, Allen F. Brooks, Naoko Ichiishi, Katarina J. Makaravage, Melanie S. Sanford, Peter J. H. Scott
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract In a relatively short period of time, transition metal-mediated radiofluorination reactions have changed the PET radiochemistry landscape. These reactions have enabled the radiofluorination of a wide range of substrates, facilitating access
Externí odkaz:
https://doaj.org/article/7daafde7551a4666b9c628beed7fc804
Autor:
Thomas Erhard, Melanie S. Sanford, Christian Bruetting, Sean S. Tanzey, Bradford D. Henderson, Andrew V. Mossine, Jason Miller, Naoko Ichiishi, Peter J. H. Scott, Allen F. Brooks, Marc B. Skaddan, Katarina J. Makaravage
Publikováno v:
Nature Protocols. 15:1742-1759
[18F]6-fluoro-L-DOPA ([18F]FDOPA) is a diagnostic radiopharmaceutical for positron emission tomography (PET) imaging that is used to image Parkinson's disease, brain tumors, and focal hyperinsulinism of infancy. Despite these important applications,
Publikováno v:
Organic Letters. 22:168-174
We report a new catalytic method for alcohol sulfamoylation that deploys electron-deficient aryl sulfamates as activated group transfer reagents. The reaction utilizes the simple organic base N-methylimidazole, proceeds under mild conditions, and pro
Autor:
Stephen Thompson, Peter Scott, Melanie S. Sanford, Isaac M. Jackson, Allen F. Brooks, So Jeong Lee, Naoko Ichiishi
Publikováno v:
Synthesis. 51:4401-4407
This communication reports a method for the vinylogous radiofluorination of α-diazoacetates to generate [18F]-γ-fluoro-α,β-unsaturated esters and ketones in moderate to good radiochemical yields. The method uses no-carrier-added [18F]AgF and is c
Autor:
Allen F. Brooks, So Jeong Lee, Katarina J. Makaravage, Peter J. H. Scott, Melanie S. Sanford, Andrew V. Mossine, Naoko Ichiishi
Publikováno v:
Chemical Communications. 55:2976-2979
This report describes a Pd-mediated C–H radiofluorination of 8-methylquinoline derivatives with no-carrier-added Ag[18F]F. To achieve this transformation, a new method was developed for the generation of Ag[18F]F using a sep-pak cartridge. The C–
Autor:
Stephen, Thompson, So Jeong, Lee, Isaac M, Jackson, Naoko, Ichiishi, Allen F, Brooks, Melanie S, Sanford, Peter J H, Scott
Publikováno v:
Synthesis (Stuttg)
This communication reports a method for the vinylogous radiofluorination of α-diazoacetates to generate γ-[(18)F]fluoro-α,β-unsaturated esters and ketones in moderate to good radiochemical yields. The method uses no-carrier-added [(18)F]AgF and i
Autor:
So Jeong, Lee, Allen F, Brooks, Naoko, Ichiishi, Katarina J, Makaravage, Andrew V, Mossine, Melanie S, Sanford, Peter J H, Scott
Publikováno v:
Chemical communications (Cambridge, England). 55(20)
This report describes a Pd-mediated C-H radiofluorination of 8-methylquinoline derivatives with no-carrier-added Ag[(18)F]F. To achieve this transformation, a new method was developed for the generation of Ag[(18)F]F using a sep-pak cartridge. The C
Publikováno v:
Organic Letters. 19:4142-4145
This report describes a method for Pd-catalyzed decarbonylative cross-coupling that enables the conversion of carboxylic acid derivatives to biaryls, aryl amines, aryl ethers, aryl sulfides, aryl boronate esters, and trifluoromethylated arenes. The s
Autor:
Andrew V, Mossine, Sean S, Tanzey, Allen F, Brooks, Katarina J, Makaravage, Naoko, Ichiishi, Jason M, Miller, Bradford D, Henderson, Marc B, Skaddan, Melanie S, Sanford, Peter J H, Scott
Publikováno v:
Org Biomol Chem
A one-pot two-step synthesis of 6-[(18)F]fluoro-L-DOPA ([(18)F]FDOPA) has been developed involving Cu-mediated radiofluorination of a pinacol boronate ester precursor. The method is fully automated, provides [(18)F]FDOPA in good activity yield (104
Autor:
Andrew V, Mossine, Sean S, Tanzey, Allen F, Brooks, Katarina J, Makaravage, Naoko, Ichiishi, Jason M, Miller, Bradford D, Henderson, Thomas, Erhard, Christian, Bruetting, Marc B, Skaddan, Melanie S, Sanford, Peter J H, Scott
Publikováno v:
Nat Protoc
[(18)F]6-Fluoro-L-DOPA ([(18)F]FDOPA), is used for diagnostic PET imaging. Using this protocol, radiofluorination of the electron-rich catechol ring can be achieved in the presence of the amino acid group by Cu-mediated fluorination of a pinacol boro