Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Naoki Osato"'
Autor:
Ryuichiro Nakato, Youichiro Wada, Ryo Nakaki, Genta Nagae, Yuki Katou, Shuichi Tsutsumi, Natsu Nakajima, Hiroshi Fukuhara, Atsushi Iguchi, Takahide Kohro, Yasuharu Kanki, Yutaka Saito, Mika Kobayashi, Akashi Izumi-Taguchi, Naoki Osato, Kenji Tatsuno, Asuka Kamio, Yoko Hayashi-Takanaka, Hiromi Wada, Shinzo Ohta, Masanori Aikawa, Hiroyuki Nakajima, Masaki Nakamura, Rebecca C. McGee, Kyle W. Heppner, Tatsuo Kawakatsu, Michiru Genno, Hiroshi Yanase, Haruki Kume, Takaaki Senbonmatsu, Yukio Homma, Shigeyuki Nishimura, Toutai Mitsuyama, Hiroyuki Aburatani, Hiroshi Kimura, Katsuhiko Shirahige
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-16 (2019)
Abstract Background Endothelial cells (ECs) make up the innermost layer throughout the entire vasculature. Their phenotypes and physiological functions are initially regulated by developmental signals and extracellular stimuli. The underlying molecul
Externí odkaz:
https://doaj.org/article/360a125b620f4aad860552d5cf426796
Autor:
Naoki Osato
Publikováno v:
BMC Genomics, Vol 19, Iss S1, Pp 135-151 (2018)
Abstract Background Transcriptional target genes show functional enrichment of genes. However, how many and how significantly transcriptional target genes include functional enrichments are still unclear. To address these issues, I predicted human tr
Externí odkaz:
https://doaj.org/article/8f1665cbab0045d791dbb81dcfbbe61b
Autor:
Tomoko M Tabuchi, Bart Deplancke, Naoki Osato, Lihua J Zhu, M Inmaculada Barrasa, Melissa M Harrison, H Robert Horvitz, Albertha J M Walhout, Kirsten A Hagstrom
Publikováno v:
PLoS Genetics, Vol 7, Iss 5, p e1002074 (2011)
DRM is a conserved transcription factor complex that includes E2F/DP and pRB family proteins and plays important roles in development and cancer. Here we describe new aspects of DRM binding and function revealed through genome-wide analyses of the Ca
Externí odkaz:
https://doaj.org/article/db6ac8aeb4324f42b60debc66370bbe5
Autor:
Chao, Zeng, Atsushi, Takeda, Kotaro, Sekine, Naoki, Osato, Tsukasa, Fukunaga, Michiaki, Hamada
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2509
With a large number of annotated non-coding RNAs (ncRNAs), repetitive sequences are found to constitute functional components (termed as repetitive elements) in ncRNAs that perform specific biological functions. Bioinformatics analysis is a powerful
Autor:
Shigeto Seno, Shoko Sakai, Tsuyoshi Goto, Yu Sheng Yeh, Teruo Kawada, Wataru Nomura, Tony Kuo, Hideo Matsuda, Haruya Takahashi, Kazuo Inoue, Paul Horton, Mari Iwase, Huei-Fen Jheng, Naoki Osato
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 84:305-313
Specific conditions, such as exposure to cold, can induce the production of brown-like adipocytes in white adipose tissue. These adipocytes express high levels of uncoupling protein 1 (UCP1) and energy expended by generating heat. Thus, these are a p
Publikováno v:
Methods in Molecular Biology ISBN: 9781071623794
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08689b1c768e046bd2d32473089254ee
https://doi.org/10.1007/978-1-0716-2380-0_19
https://doi.org/10.1007/978-1-0716-2380-0_19
Autor:
Hironori Shigeta, Yutaka Uchida, Naoki Osato, Shigeto Seno, Masaru Ishii, Junichi Kikuta, Hideo Matsuda
Publikováno v:
BIBM
Single-cell RNA-seq analysis has been widely used for revealing heterogeneity of cells in various tissues and conditions. The goal of our research is to elucidate a variety of responses of individual leukocytes in inflammatory stimulation by analyzin
Autor:
Naoki Osato, Wataru Nomura, Takako Mukai, Haruya Takahashi, Huei-Fen Jheng, Shigeto Seno, Kazuo Inoue, Yu Sheng Yeh, Hideo Matsuda, Tatsuya Kusudo, Mari Iwase, Sigenobu Matsumura, Tsuyoshi Goto, Teruo Kawada, Soshi Tokiwa
Publikováno v:
J Biol Chem
Browning of adipose tissue is induced by specific stimuli such as cold exposure and consists of up-regulation of thermogenesis in white adipose tissue. Recently, it has emerged as an attractive target for managing obesity in humans. Here, we performe
Autor:
Naoki Osato, Yoshiaki Sota, Masafumi Shimoda, Hironori Shigeta, Hideo Matsuda, Shinzaburo Noguchi, Shigeto Seno
Publikováno v:
Journal of bioinformatics and computational biology. 17(3)
Fusion genes are involved in cancer, and their detection using RNA-Seq is insufficient given the relatively short reading length. Therefore, we proposed a shifted short-read clustering (SSC) method, which focuses on overlapping reads from the same lo
Autor:
Giovanna Ambrosini, Ina Schmitt, Ullrich Wüllner, Naoki Osato, Philipp Bucher, Hongde Liu, Tikam Chand Dakal, Amit Sharma, Shailendra Asthana
Publikováno v:
Scientific reports 9(1), 18464 (2019). doi:10.1038/s41598-019-54865-w
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Parkinson disease (PD) is characterized by a pivotal progressive loss of substantia nigra dopaminergic neurons and aggregation of α-synuclein protein encoded by the SNCA gene. Genome-wide association studies identified almost 100 sequence variants l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd6a32195c571ce4385be42c7fe9b66a