Zobrazeno 1 - 10
of 297
pro vyhledávání: '"Naoki Miyata"'
Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101670- (2024)
Plant homeodomain finger protein 8 (PHF8) is a histone demethylase that regulates the expression of various genes. PHF8 targets repressor histone markers and activates gene expression. Although PHF8 has been involved in X-linked mental retardation an
Externí odkaz:
https://doaj.org/article/49904e6b7e5d43568e2acee7752c0dc3
Autor:
Naoki Miyata, Shinta Mori, Tasuku Murakami, Takahiro Bizenjima, Fumi Seshima, Kentaro Imamura, Atsushi Saito
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1664 (2024)
The aim of this study was to investigate in vivo and in vitro the effectiveness of the use of fibroblast growth factor (FGF)-2 with carbonate apatite (CO3Ap) on periodontal healing. Periodontal defects created in the maxillary first molars in rats we
Externí odkaz:
https://doaj.org/article/56cfbf95232e4390a4439995a0330df5
Autor:
Yuki Kondo, Takahiro Iwao, Sachimi Yoshihashi, Kayo Mimori, Ruri Ogihara, Kiyoshi Nagata, Kouichi Kurose, Masayoshi Saito, Takuro Niwa, Takayoshi Suzuki, Naoki Miyata, Shigeru Ohmori, Katsunori Nakamura, Tamihide Matsunaga
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104010 (2014)
In this study, we aimed to elucidate the effects and mechanism of action of valproic acid on hepatic differentiation from human induced pluripotent stem cell-derived hepatic progenitor cells. Human induced pluripotent stem cells were differentiated i
Externí odkaz:
https://doaj.org/article/3b19b0f151fd40d29f54261d116ecce7
Autor:
Takayoshi Suzuki, Yuki Kasuya, Yukihiro Itoh, Yosuke Ota, Peng Zhan, Kaori Asamitsu, Hidehiko Nakagawa, Takashi Okamoto, Naoki Miyata
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68669 (2013)
To find histone deacetylase 3 (HDAC3)-selective inhibitors, a series of 504 candidates was assembled using "click chemistry", by reacting nine alkynes bearing a zinc-binding group with 56 azide building blocks in the presence of Cu(I) catalyst. Scree
Externí odkaz:
https://doaj.org/article/d299e81947f04eb68108bf4f51d7a711
Autor:
Masahide Fukada, Atsuko Hanai, Atsuo Nakayama, Takayoshi Suzuki, Naoki Miyata, Ramona M Rodriguiz, William C Wetsel, Tso-Pang Yao, Yoshiharu Kawaguchi
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30924 (2012)
Acetylation is mediated by acetyltransferases and deacetylases, and occurs not only on histones but also on diverse proteins. Although histone acetylation in chromatin structure and transcription has been well studied, the biological roles of non-his
Externí odkaz:
https://doaj.org/article/ed3f89c89d1c48fd9245143f3d97b5d8
Autor:
Takumu OTSUBO, Naoki MIYATA, Masao IWAYA, Masaru ENDO, Naotaka NISHIO, Ruri HIDEMA, Hiroshi SUZUKI
Publikováno v:
International Journal of Refrigeration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbc8157a7be448be7e8dfddb268bba74
https://doi.org/10.1016/j.ijrefrig.2023.05.001
https://doi.org/10.1016/j.ijrefrig.2023.05.001
Autor:
Takumu Otsubo, Naoki Miyata, Masao Iwaya, Masaru Endo, Naotaka Nishio, Ruri Hidema, Hiroshi Suzuki
Publikováno v:
International Journal of Refrigeration. 138:23-30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4ca5361ece276a15c2bbf165f621ca5
https://doi.org/10.1016/j.ijrefrig.2022.03.020
https://doi.org/10.1016/j.ijrefrig.2022.03.020
Publikováno v:
Journal of Information Processing. 29:198-204
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b69f3f01faf486a0b34d40efd41b0127
https://doi.org/10.2197/ipsjjip.29.198
https://doi.org/10.2197/ipsjjip.29.198
Autor:
Kunihito Asano, Masahiro Tohkin, Keiko Maekawa, Naoki Miyata, Yoshiro Saito, Satomi Yagi, Shinsuke Iida, Makoto Osabe
Publikováno v:
Drug Metabolism and Pharmacokinetics. 35:187-190
Recently, genomic biomarkers have been widely used clinically for prediction of the efficacy and safety of pharmacotherapy and diagnosis and prognosis of pathological conditions. Therefore, genomic biomarkers are anticipated to accelerate not only pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56ee096fdd6e7d1b1d1b89ff5b14cf96
https://doi.org/10.1016/j.dmpk.2020.01.003
https://doi.org/10.1016/j.dmpk.2020.01.003
Autor:
Masahiro Tohkin, Naoki Miyata, Keiko Maekawa, Ryuzo Ueda, Shinsuke Iida, Akihiro Sekine, Masaki Ri, Yoshiro Saito, Miki Nakajima
Publikováno v:
Cancer Science
Although the proteasome inhibitor bortezomib (BTZ) shows excellent efficacy in multiple myeloma (MM), a fraction of patients has a suboptimal or no response to this agent. In addition, BTZ‐induced peripheral neuropathy (BiPN), a frequent side‐eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271ffb83580982edb6d5ab2302ad3009
http://europepmc.org/articles/PMC6778623
http://europepmc.org/articles/PMC6778623