Zobrazeno 1 - 10
of 272
pro vyhledávání: '"Naoki Kishimoto"'
Publikováno v:
Molecules, Vol 29, Iss 21, p 5050 (2024)
There is no doubt that when solid surfaces are modified, the functional groups and atoms directly bonded to solid atoms play a major role in adsorption interactions with molecules or resins. In this study, the adhesion and dissociation between epoxy
Externí odkaz:
https://doaj.org/article/060ed709669f4f2c8093a3569a847771
Autor:
Dapeng Zhang, Naoki Kishimoto
Publikováno v:
Molecules, Vol 29, Iss 21, p 5075 (2024)
Niobocene hydride–silyl complexes exhibit intriguing structural characteristics with the potential for direct hydride/silyl exchange, where hydride migration plays a crucial role during conformational interconversion. In this study, quantum chemica
Externí odkaz:
https://doaj.org/article/ad05deed1f34432f955b7d925ef401aa
Autor:
Dapeng Zhang, Naoki Kishimoto
Publikováno v:
Molecules, Vol 29, Iss 13, p 3003 (2024)
A theoretical investigation utilizing density functional theory (DFT) calculations was conducted to explore the coordination complexes formed between histidine (His) ligands and various divalent transition metal ions (Mn2+, Fe2+, Co2+, Ni2+, Cu2+, an
Externí odkaz:
https://doaj.org/article/6000af19707d48c98edd6ef63b66a60e
Autor:
Dapeng Zhang, Naoki Kishimoto
Publikováno v:
Molecules, Vol 29, Iss 12, p 2842 (2024)
This study presents a quantum chemical investigation into the structural analysis and calculated Raman spectra of modeled amylose with varying units of linked glucose molecules. We systematically examined the rotation of hydroxymethyl groups and intr
Externí odkaz:
https://doaj.org/article/a55f28786a1a4a7798c0e4596fa9f83c
Autor:
Nobuyo Higashi-Kuwata, Kohei Tsuji, Hironori Hayashi, Haydar Bulut, Maki Kiso, Masaki Imai, Hiromi Ogata-Aoki, Takahiro Ishii, Takuya Kobayakawa, Kenta Nakano, Nobutoki Takamune, Naoki Kishimoto, Shin-ichiro Hattori, Debananda Das, Yukari Uemura, Yosuke Shimizu, Manabu Aoki, Kazuya Hasegawa, Satoshi Suzuki, Akie Nishiyama, Junji Saruwatari, Yukiko Shimizu, Yoshikazu Sukenaga, Yuki Takamatsu, Kiyoto Tsuchiya, Kenji Maeda, Kazuhisa Yoshimura, Shun Iida, Seiya Ozono, Tadaki Suzuki, Tadashi Okamura, Shogo Misumi, Yoshihiro Kawaoka, Hirokazu Tamamura, Hiroaki Mitsuya
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Effective antivirals are critical for combatting SARS-CoV-2 infections. Here, the authors develop two orally available small molecules, which specifically inhibit the activity of the SARS-CoV-2 main protease and potently block the infectivity and rep
Externí odkaz:
https://doaj.org/article/0a9319e808d143a0af10cb89193b1a4f
Autor:
Aiko Sakai, Yuki Yamashita, Shogo Misumi, Naoki Kishimoto, Risako Onodera, Taishi Higashi, Hidetoshi Arima, Keiichi Motoyama
Publikováno v:
FEBS Open Bio, Vol 13, Iss 2, Pp 233-245 (2023)
Supramolecular drug carriers are a promising approach for delivering anticancer drugs with high blood retention after administration. We previously synthesized folic acid‐modified methyl‐β‐cyclodextrin (FA‐MβCD) as an anticancer drug. FA‐
Externí odkaz:
https://doaj.org/article/8d71275a5ef54afb9f834ac620d8ab3a
Autor:
Naoki Kishimoto, Ryosuke Okano, Ayano Akita, Satoshi Miura, Ayaka Irie, Nobutoki Takamune, Shogo Misumi
Publikováno v:
Retrovirology, Vol 18, Iss 1, Pp 1-9 (2021)
Abstract Background The genome of human immunodeficiency virus type 1 (HIV-1) is encapsulated in a core consisting of viral capsid proteins (CA). After viral entry, the HIV-1 core dissociates and releases the viral genome into the target cell, this p
Externí odkaz:
https://doaj.org/article/7a4c3db7f4144065b919eaad358614d4
Autor:
Shin-ichiro Hattori, Nobuyo Higashi-Kuwata, Hironori Hayashi, Srinivasa Rao Allu, Jakka Raghavaiah, Haydar Bulut, Debananda Das, Brandon J. Anson, Emma K. Lendy, Yuki Takamatsu, Nobutoki Takamune, Naoki Kishimoto, Kazutaka Murayama, Kazuya Hasegawa, Mi Li, David A. Davis, Eiichi N. Kodama, Robert Yarchoan, Alexander Wlodawer, Shogo Misumi, Andrew D. Mesecar, Arun K. Ghosh, Hiroaki Mitsuya
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Here, using in vitro assays and structural analysis, the authors characterize the anti-SARS-CoV-2 properties of two small molcules, showing these to bind and target the virus main protease (Mpro), and to exhibit a synergistic antiviral effect when co
Externí odkaz:
https://doaj.org/article/86d3e81f7e794c15baedd9ad9a968412
Autor:
Nan Chen, Ting-Hui Xiao, Zhenyi Luo, Yasutaka Kitahama, Kotaro Hiramatsu, Naoki Kishimoto, Tamitake Itoh, Zhenzhou Cheng, Keisuke Goda
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
SERS can be unreliable for biomedical use. The authors demonstrate a metal-free nanostructure composed of porous carbon nanowires in an array as a SERS substrate. It offers 106 signal enhancement due to strong broadband charge-transfer resonance and
Externí odkaz:
https://doaj.org/article/f7c745f9f85c4eedaa560f21e2c0beca
Autor:
Naoki Kishimoto, Kengo Yamamoto, Nozomi Iga, Chie Kirihara, Towa Abe, Nobutoki Takamune, Shogo Misumi
Publikováno v:
Retrovirology, Vol 17, Iss 1, Pp 1-12 (2020)
Abstract Background A protein exhibiting more than one biochemical function is termed a moonlighting protein. Glycolytic enzymes are typical moonlighting proteins, and these enzymes control the infection of various viruses. Previously, we reported th
Externí odkaz:
https://doaj.org/article/e61df32150ea48b8896661884633a6e7