Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Naoki Kakazu"'
Autor:
Tamotsu Irino, Munehiro Uemura, Humitsugu Yamane, Shigeto Umemura, Takahiko Utsumi, Naoki Kakazu, Taku Shirakawa, Mitsuhiro Ito, Takayo Suzuki, Kazuo Kinoshita
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22148 (2011)
Myeloproliferative neoplasms (MPN) are multiple disease entities characterized by clonal expansion of one or more of the myeloid lineages (i.e. granulocytic, erythroid, megakaryocytic and mast cell). JAK2 mutations, such as the common V617F substitut
Externí odkaz:
https://doaj.org/article/7a9a70c77b1f45a99950b0a6b28db6f6
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9846 (2010)
Feasibility of chromosomal manipulation in mammalian cells was first reported 15 years ago. Although this technique is useful for precise understanding of gene regulation in the chromosomal context, a limited number of laboratories have used it in ac
Externí odkaz:
https://doaj.org/article/5e275374c8c3493081c6f64bae15e696
Autor:
Hajime Hosoi, Tomoko Iehara, Kunihiko Tsuchiya, Ken Kikuchi, Satoko Tsubai-Shimizu, Yoshiki Katsumi, Shigeki Yagyu, Naoki Kakazu, Mitsuru Miyachi
Supplementary Data from Restoration of p53 Pathway by Nutlin-3 Induces Cell Cycle Arrest and Apoptosis in Human Rhabdomyosarcoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::985a42e5f141d3f05e5eb5756f5ab101
https://doi.org/10.1158/1078-0432.22440372.v1
https://doi.org/10.1158/1078-0432.22440372.v1
Autor:
Hajime Hosoi, Tomoko Iehara, Kunihiko Tsuchiya, Ken Kikuchi, Satoko Tsubai-Shimizu, Yoshiki Katsumi, Shigeki Yagyu, Naoki Kakazu, Mitsuru Miyachi
Purpose: Seventy to eighty percent of rhabdomyosarcoma (RMS) tumors retain wild-type p53. The tumor suppressor p53 plays a central role in inducing cell cycle arrest or apoptosis in response to various stresses. p53 protein levels are regulated by MD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9822d9740b5b765b26e740178f69a78f
https://doi.org/10.1158/1078-0432.c.6517710
https://doi.org/10.1158/1078-0432.c.6517710
Autor:
Kouichi, Yoshimasu, Megumi, Fujieda, Sayo, Harada, Masato, Inoue, Kazunori, Ikeda, Naoki, Kakazu, Koyo, Kojima, Masahiro, Yamada, Izumi, Kuboyama
Publikováno v:
[Nihon koshu eisei zasshi] Japanese journal of public health. 66(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf497b7608c7b588474101e393eaa695
https://pubmed.ncbi.nlm.nih.gov/31588091
https://pubmed.ncbi.nlm.nih.gov/31588091
Autor:
Shigeyuki Esumi1, Naoki Kakazu2, Yusuke Taguchi1, Teruyoshi Hirayama1, Ayako Sasaki1, Takahiro Hirabayashi3, Tsuyoshi Koide4, Takashi Kitsukawa5, Shun Hamada1, Takeshi Yagi6 yagi@fbs.osaka-u.ac.jp
Publikováno v:
Nature Genetics. Feb2005, Vol. 37 Issue 2, p171-176. 6p.
Autor:
Naoki Kakazu, Hiroko Tabata-Maruyama, Masayuki Yamasaki, Yoshinobu Nakabayahi, Akiko Misawa-Furihata, Megumi Ono, Kazuaki Tokiwa, Eriko Amaya, Humitsugu Yamane, Yasunari Tsuchihashi, Satoshi Hada, Naomi Iwai, Tomoko Iehara, Hajime Hosoi, Akio Yanagisawa, Eiichi Konishi, Tohru Sugimoto, Mitsuoki Hashiba, Tatsuo Abe, Kuninori Shiwaku, Tadashi Sawada
Publikováno v:
Cancer Genetics and Cytogenetics. 189:98-104
Rhabdomyosarcoma is the most common soft tissue tumor seen in children and young adults, and it can be classified into 2 major histological subtypes, alveolar and embryonal. In the alveolar subtype, 2 recurrent chromosomal translocations, t(2;13)(q35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b6bbc8dc99f3f0fd04ccbdead987a8
https://doi.org/10.1016/j.cancergencyto.2008.10.016
https://doi.org/10.1016/j.cancergencyto.2008.10.016
Autor:
Akira Morimoto, Naoki Kakazu, Yoko Nakase, Hajime Hosoi, Shigeki Yagyu, Shinichi Tamura, Atsushi Fujiki, Hiroshi Kuroda, Tomoko Iehara
Publikováno v:
Cancer Genetics and Cytogenetics. 180:115-120
A 17-year-old boy developed therapy-related acute myeloid leukemia (t-AML) 3 years after the cessation of chemo- and radiotherapy for undifferentiated sarcoma of the liver. At the onset of the t-AML, his white blood cell count was 900/microL with a 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4746ce1264e631aa4d802e7120bc7de4
https://doi.org/10.1016/j.cancergencyto.2007.09.023
https://doi.org/10.1016/j.cancergencyto.2007.09.023
Autor:
Ai Kotani, Daisuke Yabe, Tatsuaki Tsuruyama, Naoki Kakazu, Masamichi Muramatsu, Kazuo Kinoshita, Il-mi Okazaki, Tasuku Honjo, Hitoshi Nagaoka
Publikováno v:
Proceedings of the National Academy of Sciences. 104:1616-1620
Activation-induced cytidine deaminase (AID), which is essential to both class switch recombination and somatic hypermutation of the Ig gene, is expressed in many types of human B cell lymphoma/leukemia. AID is a potent mutator because it is involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98beb3972f3b2ded0b5178fcf608555d
https://doi.org/10.1073/pnas.0610732104
https://doi.org/10.1073/pnas.0610732104
Autor:
Anuradha Poonepalli, Koichi Akiyama, Naoki Kakazu, Kosuke Yusa, Makoto Tachibana, Yoichi Shinkai, Junji Takeda, Manoor Prakash Hande, Hideharu Hashimoto
Publikováno v:
Genes to Cells. 11:1305-1315
Some immortal cells use the alternative lengthening of telomeres (ALT) pathway to maintain their telomeres instead of telomerase. Previous studies revealed that homologous recombination (HR) contributes to the ALT pathway. To further elucidate molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52069102770306b65728b856475ceed7
https://doi.org/10.1111/j.1365-2443.2006.01020.x
https://doi.org/10.1111/j.1365-2443.2006.01020.x