Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Naoki Ishiuchi"'
Autor:
Yutaka Shinkai, Kensuke Sasaki, Ryo Tamura, Takeshi Ike, Akira Takahashi, Yosuke Osaki, Naoki Ishiuchi, Yujiro Maeoka, Ayumu Nakashima, Takao Masaki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Peritoneal inflammation and fibrosis remain major challenges to the long-term maintenance of peritoneal dialysis. Pemafibrate, a selective peroxisome proliferator-activated receptor α (PPARα) modulator, has been implicated in the managemen
Externí odkaz:
https://doaj.org/article/4e8f1357f68c473e8e51e7cb2374bc9b
Autor:
So Kurawaki, Ayumu Nakashima, Naoki Ishiuchi, Ryo Kanai, Satoshi Maeda, Kensuke Sasaki, Takao Masaki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Mesenchymal stem cells (MSCs) exert their anti-inflammatory and anti-fibrotic effects by secreting various humoral factors. Interferon-gamma (IFN-γ) can enhance these effects of MSCs, and enhancement of regulatory T (Treg) cell induction is
Externí odkaz:
https://doaj.org/article/bbb6aa0b1a0e465cae2a1c9f3bb84170
Autor:
Mitsuki Kadono, Ayumu Nakashima, Naoki Ishiuchi, Kensuke Sasaki, Yoshie Miura, Satoshi Maeda, Asuka Fujita, Ayano Sasaki, Shogo Nagamatsu, Takao Masaki
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Background Contrast-induced nephropathy (CIN) is a major clinical problem associated with acute kidney injury during hospitalization. However, effective treatments for CIN are currently lacking. Mesenchymal stem cells (MSCs) have protective
Externí odkaz:
https://doaj.org/article/5e0d418fc894447b981120964d9a6b31
Autor:
Naoki Ishiuchi, Ayumu Nakashima, Satoshi Maeda, Yoshie Miura, Kisho Miyasako, Kensuke Sasaki, Toshio Uchiki, Ayano Sasaki, Shogo Nagamatsu, Naoki Nakao, Masataka Nagao, Takao Masaki
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Background Fibrosis is a common histological feature in the process from chronic organ injury to organ failure. Chronic tissue injury causes inflammatory cell infiltration into the injured tissue. The persistence of this inflammatory cell in
Externí odkaz:
https://doaj.org/article/9afbd46581c649e9bc83666bd776f452
Autor:
Naoki Ishiuchi, Ayumu Nakashima, Shigehiro Doi, Ryo Kanai, Satoshi Maeda, Shinya Takahashi, Masataka Nagao, Takao Masaki
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-15 (2021)
Abstract Background Mesenchymal stem cells (MSCs) repair injured tissue in a paracrine manner. To enhance their therapeutic properties, preconditioning with various factors has been researched. We have previously showed that MSCs cultured in serum-fr
Externí odkaz:
https://doaj.org/article/97d70e5f27e04f8eb5c0775f282f981c
Autor:
Kazuhiro Murata, Naoki Nakao, Naoki Ishiuchi, Takafumi Fukui, Narutaka Katsuya, Wataru Fukumoto, Hiroko Oka, Naotaka Yoshikawa, Takafumi Nagao, Akira Namera, Naoya Kakimoto, Naohide Oue, Kazuo Awai, Kanji Yoshimoto, Masataka Nagao
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The global coronavirus disease 2019 (COVID-19) pandemic has led to the rapid development of vaccines against this disease. Despite the success of the international vaccination program, adverse events following vaccination, and the mechanisms behind t
Externí odkaz:
https://doaj.org/article/31b372ea4dd14b059fa047356a398d42
Autor:
Kohei Nagasaki, Ayumu Nakashima, Ryo Tamura, Naoki Ishiuchi, Kiyomasa Honda, Toshinori Ueno, Shigehiro Doi, Yukio Kato, Takao Masaki
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2021)
Abstract Background Mesenchymal stem cells (MSCs) provide potential treatments for peritoneal fibrosis. However, MSCs cultured in media containing serum bring risks of infection and other problems. In this study, we compared the effect of human MSCs
Externí odkaz:
https://doaj.org/article/f07b86702aff4dbb968fbd8eba59aad7
Autor:
Ryo Kanai, Ayumu Nakashima, Shigehiro Doi, Tomoe Kimura, Ken Yoshida, Satoshi Maeda, Naoki Ishiuchi, Yumi Yamada, Takeshi Ike, Toshiki Doi, Yukio Kato, Takao Masaki
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Mesenchymal stem cells (MSCs) administered for therapeutic purposes can be activated by interferon-γ (IFN-γ) secreted from natural killer cells in injured tissues and exert anti-inflammatory effects. These processes require a substantial p
Externí odkaz:
https://doaj.org/article/837c468c6a7d4fe9b0d5a28c99abc8c6
Autor:
Naoki Ishiuchi, Ayumu Nakashima, Shigehiro Doi, Ken Yoshida, Satoshi Maeda, Ryo Kanai, Yumi Yamada, Takeshi Ike, Toshiki Doi, Yukio Kato, Takao Masaki
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-15 (2020)
Abstract Background Mesenchymal stem cells (MSCs) have been reported to promote the regeneration of injured tissue via their paracrine abilities, which are enhanced by hypoxic preconditioning. In this study, we examined the therapeutic efficacy of hy
Externí odkaz:
https://doaj.org/article/c548a87524a24fe38ed83980cad008e7
Autor:
Farina Mohamad Yusoff, Ayumu Nakashima, Ki-ichiro Kawano, Masato Kajikawa, Shinji Kishimoto, Tatsuya Maruhashi, Naoki Ishiuchi, S. Fadilah S. Abdul Wahid, Yukihito Higashi
Publikováno v:
Stem Cells International, Vol 2022 (2022)
Hypoxia preconditioning enhances the paracrine abilities of mesenchymal stem cells (MSCs) for vascular regeneration and tissue healing. Implantation of hypoxia-induced mesenchymal stem cells (hi-MSCs) may further improve limb perfusion in a murine mo
Externí odkaz:
https://doaj.org/article/b4dd5fa9fbd8467282be801a4cdc3a56