Zobrazeno 1 - 10
of 1 019
pro vyhledávání: '"Naoki Harada"'
Autor:
Nanako Murata, Kana Nishimura, Naoki Harada, Tomoya Kitakaze, Eiji Yoshihara, Hiroshi Inui, Ryoichi Yamaji
Publikováno v:
Physiological Reports, Vol 12, Iss 12, Pp n/a-n/a (2024)
Abstract Pancreatic β‐cell mass is a critical determinant of insulin secretion. Severe endoplasmic reticulum (ER) stress causes β‐cell apoptosis; however, the mechanisms of progression and suppression are not yet fully understood. Here, we repo
Externí odkaz:
https://doaj.org/article/9af5d9aa7f5044e087cabcdccaa9575d
Autor:
Chisato Tanaka, Naoki Harada, Yoshiaki Teraoka, Hiroki Urushizaki, Yoh Shinmori, Teruaki Onishi, Yusuke Yotsumoto, Yuta Ito, Tomoya Kitakaze, Takashi Inui, Yuji Murata, Hiroshi Inui, Ryoichi Yamaji
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Target identification is a crucial step in elucidating the mechanisms by which functional food components exert their functions. Here, we identified the G-protein-coupled bile acid receptor 1 (GPBAR1, also known as TGR5) as a target of the t
Externí odkaz:
https://doaj.org/article/99b467968bce4d39b54ac8314d6bfb3e
Publikováno v:
Microorganisms, Vol 11, Iss 10, p 2377 (2023)
Endophytic prokaryotes, bacteria, and archaea, are important microorganisms that benefit host plants by promoting plant growth and reducing stress. The objective of this study was to evaluate temporal shifts in the root endophytic prokaryotic communi
Externí odkaz:
https://doaj.org/article/feb49ca7acc84b39993d50d112f74a1d
Autor:
Toru Hanamura, Shigehisa Kitano, Hiroshi Kagamu, Makiko Yamashita, Mayako Terao, Banri Tsuda, Takuho Okamura, Nobue Kumaki, Katsuto Hozumi, Naoki Harada, Takayuki Iwamoto, Chikako Honda, Sasagu Kurozumi, Naoki Niikura
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Tumor-infiltrating lymphocytes (TILs) and programmed cell death 1 ligand 1 (PD-L1) are established prognostic and predictive biomarkers for certain breast cancer subsets. However, their association with the immune response complexity is not
Externí odkaz:
https://doaj.org/article/5b61e7baafcc4346bcc32f7c5197e00c
Autor:
Naoki Harada, Mai Okuyama, Yoshiaki Teraoka, Yumi Arahori, Yoh Shinmori, Hiroko Horiuchi, Paula B. Luis, Akil I. Joseph, Tomoya Kitakaze, Shigenobu Matsumura, Tohru Hira, Norio Yamamoto, Takashi Iuni, Naoki Goshima, Claus Schneider, Hiroshi Inui, Ryoichi Yamaji
Publikováno v:
npj Science of Food, Vol 6, Iss 1, Pp 1-9 (2022)
Abstract The identification of molecular targets of bioactive food components is important to understand the mechanistic aspect of their physiological functions. Here, we have developed a screening system that enables us to determine the activation o
Externí odkaz:
https://doaj.org/article/b557c74995fa485faccc60e49ac66803
Autor:
Taro Ikeda, Masaaki Mitsutsuji, Takuya Okada, Isamu Yamada, Ryunosuke Konaka, Yukari Adachi, Akiko Matsumoto, Takahiro Wada, Naoki Harada, Masahiro Samizo
Publikováno v:
Surgical Case Reports, Vol 7, Iss 1, Pp 1-7 (2021)
Abstract Background Non-traumatic mesenteric hematomas are usually well controlled, with no resulting symptoms. Herein, we report a case in which collapse of a large mesenteric hematoma, after rupture of a right colic artery aneurysm, caused small bo
Externí odkaz:
https://doaj.org/article/f7e15bdfb0f34b54bb47163551f1fa3f
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 9035 (2023)
All-trans retinoic acid (ATRA) promotes myoblast differentiation into myotubes. Leucine-rich repeat-containing G-protein-coupled receptor 6 (LGR6) is a candidate ATRA-responsive gene; however, its role in skeletal muscles remains unclear. Here, we de
Externí odkaz:
https://doaj.org/article/a8767b058cbb48929647f3673b65810a
Autor:
Erdenetsogt Dungubat, Hiroyuki Kusano, Ichiro Mori, Hirosuke Tawara, Mitsuko Sutoh, Naoki Ohkura, Masakatsu Takanashi, Masahiko Kuroda, Naoki Harada, Emiko Udo, Masakazu Souda, Bungo Furusato, Toshio Fukusato, Yoshihisa Takahashi
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0278580 (2022)
According to previous clinical studies, the prevalence of non-alcoholic fatty liver disease (NAFLD) is higher in men than women only during the reproductive age. Animal models of NAFLD that reflect sex differences in humans have not been established.
Externí odkaz:
https://doaj.org/article/ede56826e10c4808b954d2ff2cc193a5
Autor:
Takuya Yamane, Satoshi Handa, Momoko Imai, Naoki Harada, Tatsuji Sakamoto, Tetsuo Ishida, Takenori Nakagaki, Yoshihisa Nakano
Publikováno v:
Food Chemistry: Molecular Sciences, Vol 3, Iss , Pp 100042- (2021)
Starter culture of viili contains lactic acid bacteria belonging to Lactococcus lactis. These bacteria secrete large polysaccharides (EPSs) into milk, resulting in a ropy texture of viili. In mouse experiments, a large dose of EPS (5–140 mg/day) ha
Externí odkaz:
https://doaj.org/article/70b5bef11a3948ae8877b57a50dc59cf
Publikováno v:
Soil Systems, Vol 6, Iss 2, p 54 (2022)
Environmental pollution by microplastics (MPs) has become a global problem, but little is known about MPs in soils. This is because MP extraction methods from soils have not yet been standardized. In this study, we tried to establish a simple and eco
Externí odkaz:
https://doaj.org/article/e3be6f50e7d747bab53742d6a4ad17d8