Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Naoki Akanuma"'
Autor:
Yi Xu, Michael H. Nipper, Angel A. Dominguez, Zhenqing Ye, Naoki Akanuma, Kevin Lopez, Janice J. Deng, Destiny Arenas, Ava Sanchez, Francis E. Sharkey, Colin M. Court, Aatur D. Singhi, Huamin Wang, Martin E. Fernandez-Zapico, Lu-Zhe Sun, Siyuan Zheng, Yidong Chen, Jun Liu, Pei Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Animal studies have demonstrated the ability of pancreatic acinar cells to transform into pancreatic ductal adenocarcinoma (PDAC). However, the tumorigenic potential of human pancreatic acinar cells remains under debate. To address this gap
Externí odkaz:
https://doaj.org/article/3ae4e657182c429c839f4021884860ba
Autor:
Naoki Akanuma, Nancy M. Joseph, Matthew Stachler, Spencer Behr, Toshiyuki Takahashi, Ryan M. Gill
Publikováno v:
Human Pathology Reports, Vol 29, Iss , Pp 300671- (2022)
GNAQ, GNA11, and GNA14 are paralogues in the GNAQ family that are mutually exclusively mutated in a group of vascular neoplasms with thin-walled capillary-like vasoformative growth, which occur at multiple sites. The primary liver tumor in this categ
Externí odkaz:
https://doaj.org/article/e8c5a8c157014e2580217a4392916e10
Autor:
Tetsuro Maruyama, Yasunori Akutsu, Akiko Suganami, Yutaka Tamura, Hiromichi Fujito, Tomoki Ouchi, Naoki Akanuma, Yuka Isozaki, Nobuyoshi Takeshita, Isamu Hoshino, Masaya Uesato, Taro Toyota, Hideki Hayashi, Hisahiro Matsubara
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122849 (2015)
Photodynamic therapy (PDT) is a less invasive option for cancer treatment that has evolved through recent developments in nanotechnology. We have designed and synthesized a novel liposome system that includes an indocyanine green (ICG) derivative, IC
Externí odkaz:
https://doaj.org/article/f66f8e2575f44c86a6f6e9f6cc855f44
Publikováno v:
Journal of Clinical Pathology; Mar2024, Vol. 77 Issue 3, p151-156, 6p
Autor:
Daisuke Shibahara, Naoki Akanuma, Ikei S. Kobayashi, Eunyoung Heo, Mariko Ando, Masanori Fujii, Feng Jiang, P. Nicholas Prin, Gilbert Pan, Kwok‐Kin Wong, Daniel B. Costa, Deepak Bararia, Daniel G. Tenen, Hideo Watanabe, Susumu S. Kobayashi
Publikováno v:
Cancer Science.
Publikováno v:
Modern Pathology. 36:100117
Autor:
Daisuke Jefferson Shibahara, Naoki Akanuma, Eunyoung Heo, Mariko Ando, Ikei S. Kobayashi, Masanori Fujii, Prin Paul, Gilbert Pan, Danniel G. Tenen, Hideo Watanabe, Susumu S. Kobayashi
Publikováno v:
Cancer Research. 82:3723-3723
Histone modifications play crucial roles in transcriptional activation, and aberrant epigenetic changes are associated with oncogenesis. Lysine (K) acetyltransferases 5 (KAT5) is reportedly implicated in cancer development and maintenance, although t
Autor:
Kentaro Murakami, Naoki Akanuma, Hisahiro Matsubara, Yasunori Akutsu, Masahiko Takahashi, Akihiro Usui, Yasunori Matsumoto, Takeshi Toyozumi, Aki Komatsu, Masayuki Kano, Isamu Hoshino, Nobuhumi Sekino, Hiroshi Suitoh, Naoyuki Hanari
Publikováno v:
Annals of Surgical Oncology. 24:3446-3455
The expression of Fos-related antigen 1 (Fra-1) affects tumor progression, migration, and invasion. In this study, we identified the genes regulated by Fra-1 in esophageal squamous cell carcinoma (ESCC). We constructed Fra-1 knockdown models via the
Autor:
Takayoshi Suzuki, Hisahiro Matsubara, Kentaro Murakami, Tetsuro Maruyama, Naoki Akanuma, Yasunori Matsumoto, Yuka Isozaki, Masahiko Takahashi, Isamu Hoshino, Hiroshi Suito, Yasunori Akutsu, Nobufumi Sekino, Takeshi Toyozumi, Aki Komatsu
Publikováno v:
Annals of Surgical Oncology. 23:312-320
The expression of genes can be influenced by the balance of histone acetylation and/or histone demethylation, with an imbalance of these processes possibly observed in many cancers. The histone demethylase LSD1 inhibitor activity is associated with s
Autor:
Masahiko Takahashi, Takanori Nishimori, Hiroshi Suito, Isamu Hoshino, Naoyuki Hanari, Takeshi Toyozumi, Yasunori Akutsu, Kentaro Murakami, Mikito Mori, Tetsuro Maruyama, Naoki Akanuma, Yuka Isozaki, Hisahiro Matsubara, Nobuyoshi Takeshita
Publikováno v:
International Journal of Oncology. 46:1059-1066
The aim of this study was to clarify the importance of microRNA‑375 (miR‑375) expression in patients with esophageal squamous cell carcinoma (ESCC) and to examine the in vivo antitumor effects of miR‑375 in a model of ESCC using a non‑viral d