Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Naoki, Wakiyama"'
Publikováno v:
Journal of Biosciences and Medicines. :18-23
Escherichia coli infection is important cause of morbidity and mortality. Urosepsis is most commonly caused by Escherichia coli. It is generally reported to have low mortality rates and favorable outcomes compared with sepsis induced in other organ/
Autor:
Kato Takafumi, Katsuhide Terada, Naoki Wakiyama, Yasuhiro Suzuki, Tatsuya Suzuki, Yoshito Kikkawa
Publikováno v:
Powder Technology. 280:113-118
In the pharmaceutical lubricant mixing process, lubricity of granules after mixing was evaluated by measuring the contact angle with water and tablet hardness. The granules were prepared using three different types of popular tumble mixers; V-blender
Autor:
Shinji Hasebe, Naoki Wakiyama, Manabu Kano, Hiroshi Nakagawa, Takuya Miyano, Tomoyuki Watanabe
Publikováno v:
International Journal of Pharmaceutics. 471:264-275
There has been a considerable research on the process analytical technology (PAT) and real-time monitoring based on NIR, but the model development is still an important issue and persons in charge have difficulty in building good models. In this stud
Publikováno v:
International Journal of Pharmaceutics. 469:59-66
The aim of this study was to optimize the shelf temperature and the drying time, mainly dependent on the residual water content of a lyophilized product using a novel simulation program for the secondary drying of lyophilization. The simulation progr
Publikováno v:
Advanced Powder Technology. 25:716-721
The aim of this study was to confirm whether light anhydrous silicic acid (Aerosil) could exhibit a stabilizing effect on the physical stability of solid dispersion under humidified conditions. Ternary solid dispersions consist of 50% troglitazone, a
Autor:
Yukio Wakimoto, Nanako Hata, Hiroko Wakimoto, Naoki Wakiyama, Hisako Yano, Hiroyuki Yamamoto, Chie Furubayashi, Keiko Onoue
Publikováno v:
Japanese Journal of Environmental Infections. 27:412-418
Autor:
Susumu Uchiyama, Makoto Miyajima, Jun Hasegawa, Naoki Wakiyama, Kiichi Fukui, Kei Kubota, Hirotaka Nishi
Publikováno v:
Journal of Bioscience and Bioengineering. 112:326-332
Recently, we reported that IgG1 monoclonal antibody A (MAb A) underwent liquid-liquid phase separation and separated into light and heavy phases under a low ionic strength condition. The liquid-liquid phase separation was induced due to self-associat
Autor:
Etsuo Yonemochi, Graham Buckton, Naoki Wakiyama, Shuichi Yada, Katsuhide Terada, Naho Furuyama, Takeshi Hamaura, Susumu Hasegawa
Publikováno v:
Chemical and Pharmaceutical Bulletin. 59:1452-1457
The surface of amorphous compounds crystallizes faster compared to the bulk. This suggests that molecules at the surface have high molecular mobility. Crystallization behavior is affected by various factors including molecular weight and glass transi
Autor:
Naoki Wakiyama, Katsuhide Terada, Masatomo Ito, Etsuo Yonemochi, Hiroshi Teramoto, Tatsuya Suzuki
Publikováno v:
Chemical and Pharmaceutical Bulletin. 59:868-873
A nondestructive transmittance near-infrared (NIR) method for detecting off-centered cores in dry-coated (DC) tablets was developed as a monitoring system in the DC tableting process. Caffeine anhydrate was used as a core active pharmaceutical ingred
Autor:
Michio Ohta, Nanako Hata, Masakado Matsumoto, Masaaki Minami, Tadao Hasegawa, Hideyuki Matsui, Mariko Ichikawa, Naoki Wakiyama
Publikováno v:
Current Microbiology. 62:884-887
Streptococcus dysgalactiae subsp. equisimilis isolates (n = 110) were analyzed by PCR to determine whether the gene encoding SICG, a homolog of Streptococcus pyogenes SIC, was present. Nineteen strains (17%) had this gene of which 11 (55%) were isola