Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Naoki, Umemura"'
Autor:
Swagatika Das, Praveen K. Roayapalley, Hiroshi Sakagami, Naoki Umemura, Dennis K. J. Gorecki, Mohammad Hossain, Masami Kawase, Umashankar Das, Jonathan R. Dimmock
Publikováno v:
Medicines, Vol 11, Iss 1, p 3 (2024)
Background: The objective of this study is to find novel antineoplastic agents that display greater toxicity to malignant cells than to neoplasms. In addition, the mechanisms of action of representative compounds are sought. This report describes the
Externí odkaz:
https://doaj.org/article/cddb50e03a91435d8ae782c624968b3c
Autor:
Nobuo Kondoh, Masako Mizuno-Kamiya, Naoki Umemura, Eiji Takayama, Harumi Kawaki, Kenji Mitsudo, Yasunori Muramatsu, Shinichiro Sumitomo
Publikováno v:
Japanese Dental Science Review, Vol 55, Iss 1, Pp 113-120 (2019)
Inflammation substantially affects the risk of oral malignancy. Pro-inflammatory cytokine, interferon (IFN)-γ, confers anti-tumor activity using several different mechanisms. Conversely, higher expression of interleukin (IL)-17 is associated with wo
Externí odkaz:
https://doaj.org/article/e896ecddf68045ab86c7b7d1eb007044
Autor:
Saumendra N. Sarkar, Robert L. Ferris, Pawel Kalinski, Ravikumar Muthuswamy, Paishiun N. Hsieh, Adriana Forero, Yvonne K. Mburu, Jianzhong Zhu, Naoki Umemura
PDF file - 520K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f9a4d05fdf165d20addd4be2f824fa
https://doi.org/10.1158/0008-5472.22393731.v1
https://doi.org/10.1158/0008-5472.22393731.v1
Publikováno v:
Experimental and therapeutic medicine. 24(6)
Cancer stem cells are a sub-population of cancer cells with self-renewal activity that play key roles in tumor resistance to chemotherapy and radiation. Several cancer stem cell markers have been identified to correlate with clinical prognosis. Howev
Publikováno v:
Cancer Immunology, Immunotherapy
Myeloid-derived suppressor cells (MDSCs) and tumor-associated macrophages (TAMs) are both key immunosuppressive cells that contribute to tumor growth. Metabolism and immunity of tumors depend on the tumor microenvironment (TME). However, the intracel
Autor:
Eiji Takayama, Yasunori Muramatsu, Shinichiro Sumitomo, Nobuo Kondoh, Masako Mizuno-Kamiya, Harumi Kawaki, Naoki Umemura, Kenji Mitsudo
Publikováno v:
Japanese Dental Science Review, Vol 55, Iss 1, Pp 113-120 (2019)
The Japanese Dental Science Review
The Japanese Dental Science Review
Inflammation substantially affects the risk of oral malignancy. Pro-inflammatory cytokine, interferon (IFN)-γ, confers anti-tumor activity using several different mechanisms. Conversely, higher expression of interleukin (IL)-17 is associated with wo
Autor:
Masanao Saio, Takao Takahashi, Kazuhiro Yoshida, Shinji Osada, Naoki Umemura, Kenichi Nonaka, Arizumi Kikuchi
Publikováno v:
Cellular immunology. 369
Here, we investigated the effect of Th1 polarization in the tumor microenvironment (TME) on tumor-associated macrophage (TAM) maturation and activation. In our immunotherapy mouse model, with a Th1-dominant TME, tumors regressed in all cases, with co
Autor:
Nobuo Kondoh, Masako Kamiya, Hanemi Tsuruta, Moe Takahashi, Kumiko Ikeno, Kyohei Ueno, Naoki Umemura, Eiji Takayama, Harumi Kawaki, Genjiro Nakamura, Toru Nikaido, Yasunori Muramatsu, Megumi Ando
Publikováno v:
Cancer Research. 82:5201-5201
Objectives: It has been reported that Brazilian green propolis (BGP) possesses anti-tumor and chemo-preventive properties against prostate cancer (Szliszaka E, 2011). And bioactive components from propolis have been shown to have anti-cancerous effec
In our previous study, we demonstrated that hyaluronan induces odontoblastic differentiation of dental pulp stem cells via interactions with CD44. However, it remains unclear whether CD44 expression by dental pulp stem cells is required for odontobla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d5cce9bb5301f632f30d3c32460fa8b
https://doi.org/10.1101/2020.01.27.921015
https://doi.org/10.1101/2020.01.27.921015
Autor:
Shigeki Sumi, Nobuo Kondoh, Kosuke Naganawa, Makoto Adachi, Eiji Takayama, Takahisa Ohta, Shinichiro Sumitomo, Harumi Kawaki, Naoki Umemura
Publikováno v:
Clinical and Experimental Dental Research
The aim of this research was to investigate the value of autofluorescence imaging of oral cancer across different stages of tumor growth, to assist in detecting tumors. A xenograft mouse model was created with human oral squamous cell carcinoma cell