Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Naoki, Terakawa"'
Autor:
Yutaka Osuga, Yoshifumi Seki, Masataka Tanimoto, Takeru Kusumoto, Kentarou Kudou, Naoki Terakawa
Publikováno v:
BMC Women's Health, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background Relugolix is a once-daily, oral, nonpeptide, gonadotropin-releasing hormone receptor antagonist. The aim of this study was to evaluate safety of relugolix over 24 weeks in women with endometriosis-associated pain. Methods This pha
Externí odkaz:
https://doaj.org/article/d79d8686ff0a4fb3b28ba2aec3d7b609
Autor:
Yutaka Osuga, Yoshifumi Seki, Masataka Tanimoto, Kentarou Kudou, Takeru Kusumoto, Naoki Terakawa
Publikováno v:
Fertility and Sterility. 115:397-405
Objective To evaluate the efficacy and safety of three dose levels of relugolix, a gonadotropin-releasing hormone receptor antagonist, compared with placebo and leuprorelin in women with endometriosis-associated pain. Design Phase 2, multicenter, ran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2b40de50bade03e1a097423754e095f
https://doi.org/10.1016/j.fertnstert.2020.07.055
https://doi.org/10.1016/j.fertnstert.2020.07.055
Autor:
Yoshifumi Seki, Takeru Kusumoto, Kentarou Kudou, Masataka Tanimoto, Yutaka Osuga, Naoki Terakawa
Publikováno v:
BMC Women's Health, Vol 21, Iss 1, Pp 1-8 (2021)
BMC Women's Health
BMC Women's Health
Background Relugolix is a once-daily, oral, nonpeptide, gonadotropin-releasing hormone receptor antagonist. The aim of this study was to evaluate safety of relugolix over 24 weeks in women with endometriosis-associated pain. Methods This phase 2, ran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e89cda4a93001fa990c0edc5ab9c844c
https://doi.org/10.1186/s12905-021-01393-3
https://doi.org/10.1186/s12905-021-01393-3
Autor:
Yutaka Osuga, Yoshifumi Seki, Takeru Kusumoto, Naoki Terakawa, Kentarou Kudou, Masataka Tanimoto
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7c029ad1b4b6cbcd33fb303ffd16a44
https://doi.org/10.1530/endoabs.49.gp134
https://doi.org/10.1530/endoabs.49.gp134
Autor:
Mikio Momoeda, Naoki Terakawa, Hiroshi Kobayashi, Tasuku Harada, Fuminori Taniguchi, Kunihiko Hayashi
Publikováno v:
Gynecologic and Obstetric Investigation. 77:104-110
Objective: To investigate the clinical features of patients in Japan with malignant transformation of ovarian endometrioma. Patients: Thirty-three patients diagnosed with ovarian cancer presumably arising from endometrioma were recruited retrospectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b549089d161847c73d9c41ab9064f566
https://doi.org/10.1159/000357819
https://doi.org/10.1159/000357819
Publikováno v:
Frontiers in Bioscience. :900-910
Endometriosis is an estrogen-dependent inflammatory disease. In endometriotic tissues, a high-estrogen environment associated with up-regulation of the aromatase gene has been well documented. There is accumulating evidence supporting a concept that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da50adac2c9717825438863579a91826
https://doi.org/10.2741/e669
https://doi.org/10.2741/e669
Autor:
Tasuku Harada, Yukihiro Azuma, Hiroko Higaki, Naoki Terakawa, Imari Deura, Tomio Iwabe, Fuminori Taniguchi
Publikováno v:
Gynecologic and Obstetric Investigation. 75:9-15
Aims: We investigated the potential of gonadotropin-releasing hormone (GnRH) agonists and GnRH antagonists to inhibit cell proliferation in endometriotic and endometrial stromal cells. Methods: Twenty patients with ovarian endometriomas and 18 patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ee31e231ea34f14083945bbde2464b
https://doi.org/10.1159/000343748
https://doi.org/10.1159/000343748
Autor:
Wakae Kawaguchi, Hiroaki Itamochi, Jun Naniwa, Tetsuro Oishi, Junzo Kigawa, Akiko Kudoh, Michiko Nonaka, Seiya Sato, Kazunori Uegaki, Naoki Terakawa, Shinya Sato, Muneaki Shimada, Tasuku Harada
Publikováno v:
International Journal of Gynecologic Cancer. 22:922-929
ObjectiveThis study was aimed to elucidate the roles of the mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK) and phosphatidylinositol 3′-kinase (PI3K)/Akt pathways in regulating cytotoxicity induced by cispl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e29dcae4ddbc6dfdd99405b66a13097
https://doi.org/10.1097/igc.0b013e31824f0b13
https://doi.org/10.1097/igc.0b013e31824f0b13
Publikováno v:
Fertility and Sterility. 95:1928-1931
Objective To evaluate the efficacy and safety of low-dose oral contraceptives (IKH-01; 0.035 mg ethinyl estradiol and 1 mg norethisterone) for patients with primary dysmenorrhea. Design Placebo-controlled, double-blind, randomized trial. Setting Clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6199c5cc274de8519040a3410abf409c
https://doi.org/10.1016/j.fertnstert.2011.02.045
https://doi.org/10.1016/j.fertnstert.2011.02.045
Autor:
Fuminori Taniguchi, Tomoiki Kiyama, Tasuku Harada, Yukiko Tagashira, Kana Suou, Naoki Terakawa
Publikováno v:
Fertility and Sterility. 95:1518-1521
Apigenin suppressed tumor necrosis factor α-induced cell proliferation and prostaglandin E2 expression via the attenuation of nuclear factor κB pathway in endometriotic stromal cells in vitro. Apigenin reduced the mitogenic activity and inflammator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1dcc1853a59569fb14bffe29019fb9
https://doi.org/10.1016/j.fertnstert.2010.09.046
https://doi.org/10.1016/j.fertnstert.2010.09.046