Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Naokazu Naito"'
Publikováno v:
Endocrinology. 140:3909-3918
Previously we have demonstrated that 20-kDa human GH (20K-hGH) is a full agonist for hGH receptor (hGHR) even though its complex formation with hGHR and hGH-binding protein differs from that of 22-kDa human GH (22K-hGH). In this study, we focused on
Autor:
Bunkichi Tsunekawa, Hiroshi Uchida, Shinichi Banba, Masaru Honjo, Mitsufumi Wada, Eishi Tanaka, Naokazu Naito, Miwa Ikeda, Yoshihide Hashimoto
Publikováno v:
Molecular Endocrinology. 12:146-156
In spite of recent advance in understanding of the stoichiometry of 22-kDa human GH (22K-hGH) with cell surface hGH receptor (hGHR) and hGH-binding protein (hGH-BP) circulating in human plasma, that of 20-kDa hGH (20K-hGH) is poorly understood. To cl
Autor:
Shigeki Sakata, Toichiro Hosoya, Hiroshi Nakajima, T. Nishikawa, Osamu Tarutani, K. Saito, Y. Kohno, Naokazu Naito, Hiroo Niimi
Publikováno v:
Clinical and experimental immunology. 80(1)
SUMMARY A significant portion (about 12·7%) of healthy subjects was found to contain anti-thyroglobulin (anti-Tg) antibodies in their sera. We compared the binding activities of these antibodies and of anti-Tg autoantibodies from sera of patients wi
Autor:
Naoki Shimojo, Toichiro Hosoya, Yoichi Kohno, Noriaki Suzuki, Yoshio Hiyama, Naokazu Naito, Hironori Nakajima, Hiroo Niimi, Osamu Tarutani
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 67:899-907
Monoclonal antibodies specific for human thyroid peroxidase (TPO) were prepared by the hybridoma technique using hyperimmune spleen cells from mice immunized with TPO purified from thyroid glands from patients with Graves' disease. Use of the microen
Autor:
Kanji Kuma, Hirokatsu Yoshimura, Sadaki Sakane, Kyoko Takeda, Toichiro Hosoya, Osamu Tarutani, Yoichi Kohno, Toshiji Mozai, Naokazu Naito, Junta Takamatsu
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 66:147-152
Some patients with hyperthyroid Graves' disease have increased serum T3 and normal or even low serum T4 levels during treatment with antithyroid drugs. These patients with elevated serum T3 to T4 ratios rarely have a remission of their hyperthyroidis