Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Naokazu, Sasagasako"'
Autor:
Sachiko Koyama, Kaoru Yagita, Hideomi Hamasaki, Hideko Noguchi, Masahiro Shijo, Kosuke Matsuzono, Kei-Ichiro Takase, Keita Kai, Shin-Ichi Aishima, Kyoko Itoh, Toshiharu Ninomiya, Naokazu Sasagasako, Hiroyuki Honda
Publikováno v:
Prion, Vol 18, Iss 1, Pp 40-53 (2024)
Prion disease is an infectious and fatal neurodegenerative disease. Western blotting (WB)-based identification of proteinase K (PK)-resistant prion protein (PrPres) is considered a definitive diagnosis of prion diseases. In this study, we aimed to de
Externí odkaz:
https://doaj.org/article/88736088322f420ebc3eef6459d81384
Autor:
Ken-Ichi Irie, Hiroyuki Honda, Takahisa Tateishi, Shinichiro Mori, Akifumi Yamamoto, Makoto Morimitsu, Kikuchi Shinsuke, Taiga Moritaka, Seiji Kurata, Hiroyuki Kumazoe, Masahiro Shijo, Naokazu Sasagasako, Takayuki Taniwaki
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Gerstmann–Sträussler–Scheinker (GSS) disease is an inherited prion disease characterized by dementia, cerebellar ataxia, and painful sensory disturbances. GSS is pathologically defined by the presence of amyloid plaques comprised of prion protei
Externí odkaz:
https://doaj.org/article/9f7c8a738af94856b686ac08f2456bf6
Autor:
Sachiko Koyama, Hideko Noguchi, Kaoru Yagita, Hideomi Hamasaki, Masahiro Shijo, Motoi Yoshimura, Kohei Inoshita, Naokazu Sasagasako, Hiroyuki Honda
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Prion disease is an infectious and fatal neurodegenerative disease. Human prion disease autopsy studies have revealed abnormal prion protein (PrPSc) deposits in the central nervous system and systemic organs. In deer, chronic wasting disease
Externí odkaz:
https://doaj.org/article/30347cd5ad9240edac04a0de0ecbee83
Autor:
George Umemoto, Shinsuke Fujioka, Hajime Arahata, Nobutaka Sakae, Naokazu Sasagasako, Mine Toda, Hirokazu Furuya, Yoshio Tsuboi
Publikováno v:
BMC Neurology, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Background Swallowing dysfunction is related to major cause of adverse events and an indicator of shorter survival among patients with neuromuscular disorders (NMD). It is critical to assess the swallowing function during disease progression
Externí odkaz:
https://doaj.org/article/9d07dc087c5a4a7c93fc48d8888c1dc6
Autor:
Hiroyuki Honda, Motoi Yoshimura, Hajime Arahata, Kaoru Yagita, Shoko Sadashima, Hideomi Hamasaki, Masahiro Shijo, Sachiko Koyama, Hideko Noguchi, Naokazu Sasagasako
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 82:231-241
Fused in sarcoma (FUS), coded by FUS, is a heterogeneous nuclear ribonucleoprotein (hnRNP). FUS mutations are among the major mutations in familial amyotrophic lateral sclerosis (ALS-FUS: ALS6). The pathological hallmarks of ALS-FUS are FUS-positive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d030af15b45c87aee00f3d598f001aae
https://doi.org/10.1093/jnen/nlac124
https://doi.org/10.1093/jnen/nlac124
Publikováno v:
Neuropathology. 43:117-126
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0f933d5e2d864cf702465fd1a0a45e9
https://doi.org/10.1111/neup.12862
https://doi.org/10.1111/neup.12862
Autor:
Hideomi Hamasaki, Norihisa Maeda, Naokazu Sasagasako, Hiroyuki Honda, Masahiro Shijo, Shin-Ichiro Mori, Kaoru Yagita, Hajime Arahata, Toru Iwaki
Publikováno v:
Journal of neuropathology and experimental neurology. 82(1)
Myotonic dystrophy type 1 (DM1) is an inherited autosomal-dominant condition that induces altered splicing of transcripts, including MAPT, leading to a distinctive abnormal deposition of tau protein in the CNS. We characterized the tau isoforms of ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224dc4da0646098d00d026c430cdfcd1
https://pubmed.ncbi.nlm.nih.gov/36331500
https://pubmed.ncbi.nlm.nih.gov/36331500
Autor:
Hideko Noguchi, Sachiko Koyama, Kaoru Yagita, Masahiro Shijo, Kosuke Matsuzono, Hideomi Hamasaki, Takaaki Kanemaru, Tsuyoshi Okamoto, Keita Kai, Shinichi Aishima, Koji Abe, Naokazu Sasagasako, Hiroyuki Honda
Publikováno v:
Journal of neuropathology and experimental neurology. 82(1)
GPI anchorless prion diseases (GPIALPs) show numerous coarse prion protein (PrP) deposits in the CNS but neuropil spongiform changes are mild and the incidence of dementia is low. Here, we examined differences in resident microglial phenotypes betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d3cd84a3aa1d592f24fb7926b72590
https://pubmed.ncbi.nlm.nih.gov/36331509
https://pubmed.ncbi.nlm.nih.gov/36331509
Autor:
Kaoru Yagita, Hideko Noguchi, Sachiko Koyama, Hideomi Hamasaki, Takashi Komori, Shinichi Aishima, Takayuki Kosaka, Mitsuharu Ueda, Yoshihiro Komohara, Akihiro Watanabe, Naokazu Sasagasako, Toshiharu Ninomiya, Yoshinao Oda, Hiroyuki Honda
Publikováno v:
Journal of neuropathology and experimental neurology. 81(11)
The differential effects of sporadic Creutzfeldt-Jakob disease (sCJD) on the hippocampus and other neocortical areas are poorly understood. We aimed to reveal the histological patterns of cellular prion protein (PrPC) and abnormal prion protein (PrPS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa27eb7d99593c7cdee5be17895036c
https://pubmed.ncbi.nlm.nih.gov/36063412
https://pubmed.ncbi.nlm.nih.gov/36063412
Autor:
Trang Đồng, Shoko Sadashima, Katsuya Satoh, Akihiro Watanabe, Hiroyuki Honda, Noriyuki Nishida, Shinichiro Mori, Toru Iwaki, Naokazu Sasagasako
Publikováno v:
Neuropathology. 41:152-158
We report the general autopsy findings of abnormal prion protein (PrP) deposits with their seeding activities, as assessed by the real-time quaking-induced conversion (RT-QuIC) method, in a 72-year-old female patient with sporadic Creutzfeldt-Jakob d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47c1bbd5a0bb50b4d304e5e1b7c51dd1
https://doi.org/10.1111/neup.12717
https://doi.org/10.1111/neup.12717