Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Naohito, Shimoyama"'
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 45:667-673
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4e229328ae78489690c4e54dce311bf
https://doi.org/10.5649/jjphcs.45.667
https://doi.org/10.5649/jjphcs.45.667
Autor:
Naohito Shimoyama, Megumi Shimoyama
Publikováno v:
THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA. 38:783-789
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bee9f8ac5cd214ead1059c100d5a305a
https://doi.org/10.2199/jjsca.38.783
https://doi.org/10.2199/jjsca.38.783
Autor:
Yugo Tagaito, Naohito Shimoyama, Hiroshi Nagase, Satoshi Toyama, Tsuyoshi Saitoh, Masashi Yanagisawa, Megumi Shimoyama
Publikováno v:
Anesthesiology. 128:992-1003
Background Sleepiness and decrease in attention are dose-limiting side effects of opioids. The orexin/hypocretin system plays an important role in maintaining wakefulness. This study aimed to explore the potential of a nonpeptide orexin receptor agon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f1d7ca3ee1b8f1710ac7e9732bb3d4
https://doi.org/10.1097/aln.0000000000002161
https://doi.org/10.1097/aln.0000000000002161
Autor:
Daisuke Nishizawa, Makoto Nagashima, Ryoji Katoh, Yasuo Satoh, Megumi Tagami, Shinya Kasai, Yasukazu Ogai, Wenhua Han, Junko Hasegawa, Naohito Shimoyama, Ichiro Sora, Masakazu Hayashida, Kazutaka Ikeda
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7060 (2009)
Opioids are commonly used as effective analgesics for the treatment of acute and chronic pain. However, considerable individual differences have been widely observed in sensitivity to opioid analgesics. We focused on a G-protein-activated inwardly re
Externí odkaz:
https://doaj.org/article/434eddbd4a374599a90da43805e5f042
Autor:
Megumi, Shimoyama, Naohito, Shimoyama
Publikováno v:
Masui. The Japanese journal of anesthesiology. 65(11)
Recently in Japan, more patients are receiving chronic opioid therapy for cancer pain or chronic pain, and there is an increasing number of such patients presenting for surgery. The anesthesiologist should be familiar with available opioid formulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a86c26e220af4496d23c72604216fc2
https://pubmed.ncbi.nlm.nih.gov/30351799
https://pubmed.ncbi.nlm.nih.gov/30351799
Publikováno v:
ACS chemical neuroscience. 9(7)
Several chemotherapeutic agents used for cancer treatment induce dose-limiting peripheral neuropathy that compromises patients’ quality of life and limits cancer treatment. Recently, mitochondrial dysfunction has been shown to be involved in the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba0e66752cf200a41017e5634019b29
https://pubmed.ncbi.nlm.nih.gov/29660270
https://pubmed.ncbi.nlm.nih.gov/29660270
Autor:
Hidenori Sasaki, Makoto Wada, Koichi Hirata, Tadashi Ikeda, Toshiaki Saeki, Akifumi Yamamoto, Yoshikazu Kagami, Yutaka Okawa, Naohito Shimoyama, Masayuki Takeda, Toshihiko Nishidate, Yasuhiro Udagawa, Kazuo Tamura, Narikazu Boku, Kenjiro Aogi, Yasuo Shima, Keisuke Aiba, Hirofumi Fujii, Kazuhiko Nakagawa, Kenji Eguchi, Hideki Takeuchi, Kenji Okita, Ryuhei Tanaka, Yusuke Onozawa, Tatsuo Akechi
Publikováno v:
International Journal of Clinical Oncology
The purpose of this article is to disseminate the standard of antiemetic therapy for Japanese clinical oncologists. On the basis of the Appraisal of Guidelines for Research and Evaluation II instrument, which reflects evidence-based clinical practice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91cc0122a5cfb54bd39bd4e70991347
https://doi.org/10.1007/s10147-015-0852-1
https://doi.org/10.1007/s10147-015-0852-1
Publikováno v:
Chemical Biology & Drug Design. 80:771-774
H-Dmt-D-Arg-Phe-Lys-NH(2) ([Dmt(1)]DALDA) is a synthetic tetrapeptide with extraordinary selectivity for the mu-opioid receptor and is an extremely potent analgesic. [Dmt(1) ]DALDA is unusual in the way that the greater part of its analgesic potency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14e046801c2e73aaff0845a870a17891
https://doi.org/10.1111/cbdd.12003
https://doi.org/10.1111/cbdd.12003
Publikováno v:
Pharmacology. 89:145-148
Background/Aims: Multiple opioid receptor (OR) types and endogenous opioid peptides exist in the spinal dorsal horn and there may be interactions among these receptor types that involve opioid peptides. In a previous study we observed that antinocice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c35bfb02f7afb82db004e940823df8a
https://doi.org/10.1159/000336770
https://doi.org/10.1159/000336770
Autor:
Naohito SHIMOYAMA, Akitaka YOSHIZAWA
Publikováno v:
THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA. 38:770-770
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40475cdf1c306da7108ca8b72ba2a73b
https://doi.org/10.2199/jjsca.38.770
https://doi.org/10.2199/jjsca.38.770