Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Naohisa Kitade"'
Autor:
Keita Fukao, Takeshi Noshi, Shinya Shano, Kaoru Baba, Kenji Sato, Masashi Sakuramoto, Naohisa Kitade, Hideki Tanioka, Shinji Kusakabe, Takao Shishido
Publikováno v:
Viruses, Vol 15, Iss 11, p 2264 (2023)
Influenza remains a worldwide health concern. Antiviral drugs are considered as one of the useful options for its prevention as a complementary measure to vaccination. Baloxavir acid selectively inhibits the cap-dependent endonuclease of influenza vi
Externí odkaz:
https://doaj.org/article/3d0f8d5ec5c64235aeaaa042d9b2f1f0
Autor:
Akira Matsumura, Naohisa Kitade, Shingo Sakamoto, Atsuyuki Shimazaki, Yutaka Tonomura, Akira Ino, Naotake Kobayashi, Yuji Nishiura, Takayuki Okuno
Publikováno v:
Bioorganicmedicinal chemistry letters. 28(14)
Novel acetyl-CoA carboxylase 2 (ACC2) selective inhibitors were identified by the conversion of the alkyne unit of A-908292 to the olefin linker. Modification of the center and left part of the lead compound 1b improved the ACC2 inhibitory activity a
Autor:
Kei Mayumi, Takeshi Kasuya, Tatsuya Ikehara, Naohisa Kitade, Ayahisa Watanabe, Reina Onishi, Akira Kugimiya, Mado Nakajima
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 357(2)
TriantennaryN-acetyl galactosamine (GalNAc, GN3) and lipophilic ligands such as cholesterol andα-tocopherol conjugations dramatically improve the distribution and efficacy of second-generation antisense oligonucleotides (ASOs) in the whole liver. To
Autor:
Masatoshi Tomi, Shirou Hirose, Masanori Tachikawa, Shin Ichi Akanuma, Naohisa Kitade, Noriko Yokota, Ken Ichi Hosoya
Publikováno v:
Journal of Neurochemistry. 111:716-725
The purpose of this study was to identify the transporter mediating l-arginine transport at the inner blood–retinal barrier (BRB). The apparent uptake clearance of [3H]l-arginine into the rat retina was found to be 118 μL/(min·g retina), supporti
Autor:
Masatoshi, Tomi, Naohisa, Kitade, Shirou, Hirose, Noriko, Yokota, Shin-Ichi, Akanuma, Masanori, Tachikawa, Ken-ichi, Hosoya
Publikováno v:
Journal of neurochemistry. 111(3)
The purpose of this study was to identify the transporter mediating l-arginine transport at the inner blood-retinal barrier (BRB). The apparent uptake clearance of [(3)H]L-arginine into the rat retina was found to be 118 microL/(min.g retina), suppor
Autor:
Fukao, Keita1 (AUTHOR) shinji.kusakabe@shionogi.co.jp, Noshi, Takeshi1 (AUTHOR), Shano, Shinya2 (AUTHOR), Baba, Kaoru2 (AUTHOR), Sato, Kenji1 (AUTHOR), Sakuramoto, Masashi1 (AUTHOR), Kitade, Naohisa1 (AUTHOR), Tanioka, Hideki1 (AUTHOR), Kusakabe, Shinji1 (AUTHOR), Shishido, Takao1 (AUTHOR) takao.shishido@shionogi.co.jp
Publikováno v:
Viruses (1999-4915). Nov2023, Vol. 15 Issue 11, p2264. 13p.
Autor:
Hashimoto, Takashi1,2 (AUTHOR), Baba, Keiko1 (AUTHOR), Inoue, Kae2 (AUTHOR), Okane, Miyako2 (AUTHOR), Hata, Satoshi2 (AUTHOR), Shishido, Takao1 (AUTHOR), Naito, Akira1 (AUTHOR), Wildum, Steffen3 (AUTHOR), Omoto, Shinya1 (AUTHOR) shinya.oomoto@shionogi.co.jp
Publikováno v:
Influenza & Other Respiratory Viruses. May2021, Vol. 15 Issue 3, p389-395. 7p.
Autor:
Kitano, Mitsutaka1 (AUTHOR) mitsutaka.kitano@shionogi.co.jp, Matsuzaki, Takanobu1 (AUTHOR), Oka, Ryoko1 (AUTHOR), Baba, Kaoru2 (AUTHOR), Noda, Takahiro2 (AUTHOR), Yoshida, Yuki1 (AUTHOR), Sato, Kenji1 (AUTHOR), Kiyota, Kohei1 (AUTHOR), Mizutare, Tohru1 (AUTHOR), Yoshida, Ryu1 (AUTHOR), Sato, Akihiko1 (AUTHOR), Kamimori, Hiroshi1 (AUTHOR), Shishido, Takao1 (AUTHOR), Naito, Akira1 (AUTHOR)
Publikováno v:
Influenza & Other Respiratory Viruses. Nov2020, Vol. 14 Issue 6, p710-719. 10p.
Autor:
Baba, Keiko1 (AUTHOR), Oka, Ryoko1 (AUTHOR), Shano, Shinya1 (AUTHOR), Omoto, Shinya1 (AUTHOR) shinya.oomoto@shionogi.co.jp, Noshi, Takeshi1 (AUTHOR), Shishido, Takao1 (AUTHOR), Naito, Akira1 (AUTHOR), Kawaguchi, Keiko1 (AUTHOR), Ishibashi, Toru1 (AUTHOR), Uehara, Takeki1 (AUTHOR)
Publikováno v:
Influenza & Other Respiratory Viruses. May2020, Vol. 14 Issue 3, p353-357. 5p.
Publikováno v:
Drug Week; 12/8/2023, p2614-2614, 1p