Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Naohisa, Ogo"'
Autor:
Naohiro Yanagimura, Shinji Takeuchi, Koji Fukuda, Sachiko Arai, Azusa Tanimoto, Akihiro Nishiyama, Naohisa Ogo, Hiroyuki Takahashi, Akira Asai, Satoshi Watanabe, Toshiaki Kikuchi, Seiji Yano
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-12 (2022)
Abstract Patients with advanced anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer who are prescribed ALK-tyrosine kinase inhibitors (ALK-TKIs) rarely have complete responses, with residual tumors relapsing as heterogeneous resist
Externí odkaz:
https://doaj.org/article/96cbee869e9e46158e3c0f9d71481295
Autor:
Eriko Hamasaki, Natsuki Wakita, Hiroki Yasuoka, Hikaru Nagaoka, Masayuki Morita, Eizo Takashima, Takayuki Uchihashi, Tetsuya Takeda, Tadashi Abe, Ji-Won Lee, Tadahiro Iimura, Moin A Saleem, Naohisa Ogo, Akira Asai, Akihiro Narita, Kohji Takei, Hiroshi Yamada
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Dynamin is an endocytic protein that functions in vesicle formation by scission of invaginated membranes. Dynamin maintains the structure of foot processes in glomerular podocytes by directly and indirectly interacting with actin filaments. However,
Externí odkaz:
https://doaj.org/article/d8d684637941406b9a5dac408770ee49
Autor:
Hiroaki Ikeda, Hideo Yagita, Hiroshi Mukae, Kiyoshi Yasui, Yosuke Dotsu, Naohisa Ogo, Yudai Sonoda, Hiroyuki Yamaguchi, Akira Asai, Daisuke Muraoka
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Background Cancer immunotherapy shows insufficient efficacy for low immunogenic tumors. Furthermore, tumors often downregulate antigen and major histocompatibility complex expression to escape recognition by T cells, resulting in insufficient T cell
Externí odkaz:
https://doaj.org/article/634e0b99605146a39b58b3eb89b397fe
Autor:
Satoshi Shimizu, Miho Yamada, Takahiro Katagiri, Yoichi Sunagawa, Yasufumi Katanasaka, Yusuke Miyazaki, Masafumi Funamoto, Sari Nurmila, Kana Shimizu, Naohisa Ogo, Akira Asai, Koji Hasegawa, Tatsuya Morimoto
Publikováno v:
European Cardiology Review, Vol 16, Iss , Pp - (2021)
Externí odkaz:
https://doaj.org/article/0a6ff42675f54a0b8898faa6555af0cc
Publikováno v:
FEBS Letters. 597:1138-1148
Publikováno v:
Physiological Reports, Vol 8, Iss 20, Pp n/a-n/a (2020)
Abstract Kidney fibrosis is a histological hallmark of chronic kidney disease (CKD) and is believed to be involved in the progression of CKD. Therefore, inhibition of kidney fibrosis is a potential strategy for slowing CKD progression. Signal transdu
Externí odkaz:
https://doaj.org/article/6b402338a51d4a3db35c3f64b1825953
Autor:
Hideshi Yokoyama, Jun-ichi Sawada, Kohei Sato, Naohisa Ogo, Nanami Kamei, Yoshinobu Ishikawa, Kodai Hara, Akira Asai, Hiroshi Hashimoto
Publikováno v:
ACS Omega, Vol 3, Iss 9, Pp 12284-12294 (2018)
Externí odkaz:
https://doaj.org/article/31862f55eba44f1988de2f9cb8007e6b
Autor:
Hiroyuki Takahashi, Nao Miyoshi, Hisashi Murakami, Yuta Okamura, Naohisa Ogo, Akimitsu Takagi, Daisuke Muraoka, Akira Asai
Publikováno v:
Cancer Immunology, Immunotherapy.
Autor:
Kazunori Iwamoto, Yutaka Uehara, Yukie Inoue, Kyoko Taguchi, Daisuke Muraoka, Naohisa Ogo, Kenji Matsuno, Akira Asai
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170709 (2017)
Bendamustine (BENDA), which bears the bis(2-chloroethyl)amino moiety, is an alkylating agent that stops the growth of cancer cells by binding to DNA and interfering with its replication. However, the mechanism of action underlying its excellent clini
Externí odkaz:
https://doaj.org/article/bf860007ca6c49be8d5ff1910c64fb75
Autor:
Saeko Yoshioka, Tomonori Ikeda, Sogo Fukuchi, Yurika Kawai, Katsumi Ohta, Hisashi Murakami, Naohisa Ogo, Daisuke Muraoka, Osamu Takikawa, Akira Asai
Publikováno v:
International journal of tryptophan research : IJTR. 15
Kynurenine (Kyn), a metabolite of tryptophan (Trp), is a key regulator of mammal immune responses such as cancer immune tolerance. Indoleamine-2,3-dioxygenase (IDO) and tryptophan-2,3-dioxygenase (TDO) are main enzymes regulating the first and rate-l