Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Naohisa, Kitade"'
Autor:
Keita Fukao, Takeshi Noshi, Shinya Shano, Kaoru Baba, Kenji Sato, Masashi Sakuramoto, Naohisa Kitade, Hideki Tanioka, Shinji Kusakabe, Takao Shishido
Publikováno v:
Viruses, Vol 15, Iss 11, p 2264 (2023)
Influenza remains a worldwide health concern. Antiviral drugs are considered as one of the useful options for its prevention as a complementary measure to vaccination. Baloxavir acid selectively inhibits the cap-dependent endonuclease of influenza vi
Externí odkaz:
https://doaj.org/article/3d0f8d5ec5c64235aeaaa042d9b2f1f0
Autor:
Akira Matsumura, Naohisa Kitade, Shingo Sakamoto, Atsuyuki Shimazaki, Yutaka Tonomura, Akira Ino, Naotake Kobayashi, Yuji Nishiura, Takayuki Okuno
Publikováno v:
Bioorganicmedicinal chemistry letters. 28(14)
Novel acetyl-CoA carboxylase 2 (ACC2) selective inhibitors were identified by the conversion of the alkyne unit of A-908292 to the olefin linker. Modification of the center and left part of the lead compound 1b improved the ACC2 inhibitory activity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc357ddc5a313b101e7b21de54f08fe
https://pubmed.ncbi.nlm.nih.gov/29903660
https://pubmed.ncbi.nlm.nih.gov/29903660
Autor:
Kei Mayumi, Takeshi Kasuya, Tatsuya Ikehara, Naohisa Kitade, Ayahisa Watanabe, Reina Onishi, Akira Kugimiya, Mado Nakajima
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 357(2)
TriantennaryN-acetyl galactosamine (GalNAc, GN3) and lipophilic ligands such as cholesterol andα-tocopherol conjugations dramatically improve the distribution and efficacy of second-generation antisense oligonucleotides (ASOs) in the whole liver. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a8608728cb8073061b58e1bed581dbf
https://pubmed.ncbi.nlm.nih.gov/26907624
https://pubmed.ncbi.nlm.nih.gov/26907624
Autor:
Masatoshi Tomi, Shirou Hirose, Masanori Tachikawa, Shin Ichi Akanuma, Naohisa Kitade, Noriko Yokota, Ken Ichi Hosoya
Publikováno v:
Journal of Neurochemistry. 111:716-725
The purpose of this study was to identify the transporter mediating l-arginine transport at the inner blood–retinal barrier (BRB). The apparent uptake clearance of [3H]l-arginine into the rat retina was found to be 118 μL/(min·g retina), supporti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8332c9cb9d3bca9d644480d24c6894e4
https://doi.org/10.1111/j.1471-4159.2009.06367.x
https://doi.org/10.1111/j.1471-4159.2009.06367.x
Autor:
Masatoshi, Tomi, Naohisa, Kitade, Shirou, Hirose, Noriko, Yokota, Shin-Ichi, Akanuma, Masanori, Tachikawa, Ken-ichi, Hosoya
Publikováno v:
Journal of neurochemistry. 111(3)
The purpose of this study was to identify the transporter mediating l-arginine transport at the inner blood-retinal barrier (BRB). The apparent uptake clearance of [(3)H]L-arginine into the rat retina was found to be 118 microL/(min.g retina), suppor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09eb65750e4560d2c714544374184e97
https://pubmed.ncbi.nlm.nih.gov/19712052
https://pubmed.ncbi.nlm.nih.gov/19712052