Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Naohiro Uraoka"'
Autor:
Go Kobayashi, Tetsutaro Hayashi, Kazuhiro Sentani, Naohiro Uraoka, Takafumi Fukui, Aya Kido, Narutaka Katsuya, Akira Ishikawa, Takashi Babasaki, Yohei Sekino, Hiroyuki Nose, Koji Arihiro, Nobuyuki Hinata, Naohide Oue
Publikováno v:
Diagnostic Pathology, Vol 18, Iss 1, Pp 1-14 (2023)
Abstract Background We previously reported Minichromosome maintenance 4 (MCM4) overexpression in gastric cancer. However, the clinicopathological significance of MCM4 in urothelial carcinoma (UC) has not been investigated. To clarify the clinicopatho
Externí odkaz:
https://doaj.org/article/516f0a464ef843f6b0d12a1723c1bf82
Autor:
Akira Ishikawa, Naohiro Uraoka, Jun Shibata, Ryosuke Nobuhiro, Go Kobayashi, Yoichi Saito, Hiroyuki Nose, Naohide Oue
Publikováno v:
Case Reports in Oncology, Vol 16, Iss 1, Pp 82-87 (2023)
Bilateral synchronous paratesticular leiomyoma (BSPL) is a rare tumor that originates from smooth muscle cells in the paratesticular region. Four BSPL cases have been reported sporadically, starting with the 1991 report by Aus and Boiesen. Herein, we
Externí odkaz:
https://doaj.org/article/f023606ea9854f2894eead19b920e51d
Autor:
Ziv Frankenstein, Naohiro Uraoka, Umut Aypar, Ruth Aryeequaye, Mamta Rao, Meera Hameed, Yanming Zhang, Yukako Yagi
Publikováno v:
Applied Microscopy, Vol 51, Iss 1, Pp 1-12 (2021)
Abstract Fluorescence in situ hybridization (FISH) is a technique to visualize specific DNA/RNA sequences within the cell nuclei and provide the presence, location and structural integrity of genes on chromosomes. A confocal Whole Slide Imaging (WSI)
Externí odkaz:
https://doaj.org/article/92558dbc5b3d442fa3c721e0c5a341ef
Autor:
Kazuhiro Tabata, Naohiro Uraoka, Jamal Benhamida, Matthew G. Hanna, Sahussapont Joseph Sirintrapun, Brandon D. Gallas, Qi Gong, Rania G. Aly, Katsura Emoto, Kant M. Matsuda, Meera R. Hameed, David S. Klimstra, Yukako Yagi
Publikováno v:
Diagnostic Pathology, Vol 14, Iss 1, Pp 1-9 (2019)
Abstract Background The establishment of whole-slide imaging (WSI) as a medical diagnostic device allows that pathologists may evaluate mitotic activity with this new technology. Furthermore, the image digitalization provides an opportunity to develo
Externí odkaz:
https://doaj.org/article/3288f48a24204df6b00d57d838a52f8d
Autor:
Edwin R. Parra, Naohiro Uraoka, Mei Jiang, Pamela Cook, Don Gibbons, Marie-Andrée Forget, Chantale Bernatchez, Cara Haymaker, Ignacio I. Wistuba, Jaime Rodriguez-Canales
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Immune-profiling is becoming an important tool to identify predictive markers for the response to immunotherapy. Our goal was to validate multiplex immunofluorescence (mIF) panels to apply to formalin-fixed and paraffin-embedded tissues usin
Externí odkaz:
https://doaj.org/article/48f248acce0f4bd68d965c4ec09c5ab2
Autor:
Souptik Barua, Luisa Solis, Edwin Roger Parra, Naohiro Uraoka, Mei Jiang, Huamin Wang, Jaime Rodriguez-Canales, Ignacio Wistuba, Anirban Maitra, Subrata Sen, Arvind Rao
Publikováno v:
Cancer Informatics, Vol 17 (2018)
Intraductal papillary mucinous neoplasms (IPMNs), critical precursors of the devastating tumor pancreatic ductal adenocarcinoma (PDAC), are poorly understood in the pancreatic cancer community. Researchers have shown that IPMN patients with high-grad
Externí odkaz:
https://doaj.org/article/9656e30d48dd44ec90115028d4cc73d3
Autor:
William N. William, Jianjun Zhang, Xin Zhao, Edwin R. Parra, Naohiro Uraoka, Heather Y. Lin, S. Andrew Peng, Adel K. El‐Naggar, Jaime Rodriguez‐Canales, Jaejoon Song, Ann M. Gillenwater, Ignacio I. Wistuba, Jeffrey N. Myers, Kathryn A. Gold, Renata Ferrarotto, Patrick Hwu, Teresa Davoli, J. Jack Lee, John V. Heymach, Vassiliki A. Papadimitrakopoulou, Scott M. Lippman
Publikováno v:
Cancer. 129:714-727
Studies of the immune landscape led to breakthrough trials of programmed death-1 (PD-1) inhibitors for recurrent/metastatic head and neck squamous cell carcinoma therapy. This study investigated the timing, influence of somatic copy-number alteration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a76430949630ce38768c9b442fcf082d
https://doi.org/10.1002/cncr.34607
https://doi.org/10.1002/cncr.34607
Autor:
Narutaka Katsuya, Akira Ishikawa, Aya Kido, Takafumi Fukui, Go Kobayashi, Yohei Sekino, Naohiro Uraoka, Takashi Babasaki, Wataru Yasui, Kazuhiro Sentani, Naohide Oue
Publikováno v:
Pathobiology. :1-8
Introduction: Gastric cancer (GC) is a leading cause of cancer-related death worldwide. This study focused on minichromosome maintenance 4 (MCM4), a DNA helicase component that functions in DNA replication. Using spheroid colony formation, having a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bae96c48efdb932e7715f1f3c93230d
https://doi.org/10.1159/000525590
https://doi.org/10.1159/000525590
Autor:
Subrata Sen, Luisa M. Solis, Anirban Maitra, Ignacio I. Wistuba, Huamin Wang, Eugene J. Koay, Sean J. Mulvihill, Matthew A. Firpo, C. Max Schmidt, Michele Yip-Schneider, Courtney L. Scaife, Kajsa Affolter, Cara Haymaker, Renganayaki Pandurengan, Wei Lu, Barbara Mino, Shanyu Zhang, Mei Jiang, Wei Qiao, Yu Shen, Ximing Tang, Naohiro Uraoka, Edwin Roger Parra, Sharia Hernandez
Purpose:Intraductal papillary mucinous neoplasms (IPMN) are bona fide precursors to pancreatic ductal adenocarcinoma (PDAC). While genomic alterations during multistep IPMN progression have been well cataloged, the accompanying changes within the tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cec114744f7cfb3e44b3811e9ddfc80
https://doi.org/10.1158/1078-0432.c.6531288
https://doi.org/10.1158/1078-0432.c.6531288
Autor:
Chantale Bernatchez, Cara Haymaker, Anirban Maitra, Patrick Hwu, Jianhua Zhang, Timothy P. Heffernan, Hector A. Alvarez, Michael J. Overman, Milind Javle, Gauri Varadhachary, Jason B. Fleming, Jaime Rodriguez-Canales, Christopher A. Bristow, Ya'an Kang, Edwin Roger Parra, Naohiro Uraoka, Mark W. Hurd, Young Uk Kim, Li Zhao, Vincent Bernard, Caitlin Creasy, Marie-Andrée Forget, Donastas Sakellariou-Thompson
Supplementary material and method Supplementary Figure S1. Addition of a4-1BB does not lead CD8+ TIL into senescence. Supplementary Figure S2. Fold expansion of bulk and CD8+ PDAC TIL following the REP. Supplementary Figure S3. Level of MHC class I e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ffd5dfa3352deb70ac0bbec325dc10e
https://doi.org/10.1158/1078-0432.22467081
https://doi.org/10.1158/1078-0432.22467081