Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Naohiro NOMURA"'
Publikováno v:
Case Reports in Pediatrics, Vol 2023 (2023)
Growth Hormone therapy has been shown to induce transient insulin resistance in children, and there is concern regarding the diabetogenic potential of GH therapy in children born small for gestational age (SGA). In this case, female patient born SGA
Externí odkaz:
https://doaj.org/article/94c09034d9a1452e991c3b0095141821
Autor:
Masayuki Sasahara, Hiroki Takahashi, Takashi Ohchi, Naohiro Nomura, Kentaro Kodama, Kimiyuki Ikeda, Hirotaka Nishikiori, Kenzo Okamoto, Hirofumi Chiba
Publikováno v:
Medicina, Vol 59, Iss 3, p 631 (2023)
Spontaneous lung cancer regression is a very rare course of disease. A 60-year-old male patient was admitted to our hospital with pneumonia and a 19 mm-sized nodule shadow in the S4 of the left lung on chest computed tomography (CT). A percutaneous n
Externí odkaz:
https://doaj.org/article/823c032f1946486b90dab633364240a8
Autor:
Wakana Shoda, Naohiro Nomura, Fumiaki Ando, Hideaki Tagashira, Takahiro Iwamoto, Akihito Ohta, Kiyoshi Isobe, Takayasu Mori, Koichiro Susa, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0235360 (2020)
The sodium (Na+)-chloride cotransporter (NCC) expressed in the distal convoluted tubule (DCT) is a key molecule regulating urinary Na+ and potassium (K+) excretion. We previously reported that high-K+ load rapidly dephosphorylated NCC and promoted ur
Externí odkaz:
https://doaj.org/article/d2729c341b9d4e17acb6dfd724a6bd1b
Autor:
Fumiaki Ando, Shuichi Mori, Naofumi Yui, Tetsuji Morimoto, Naohiro Nomura, Eisei Sohara, Tatemitsu Rai, Sei Sasaki, Yoshiaki Kondo, Hiroyuki Kagechika, Shinichi Uchida
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Patients suffering from congenital nephrogenic diabetes insipidus (NDI) fail to concentrate urine due to mutations in vasopressin type 2 receptor (V2R). Here Ando et al. show that agents disrupting the interaction between PKA and AKAPs restore aquapo
Externí odkaz:
https://doaj.org/article/8c60b14a92e94b27bd57f69fed3d984d
Autor:
Shintaro Mandai, Hidehiko Sato, Soichiro Iimori, Shotaro Naito, Takayasu Mori, Daiei Takahashi, Moko Zeniya, Naohiro Nomura, Eisei Sohara, Tomokazu Okado, Shinichi Uchida, Kiyohide Fushimi, Tatemitsu Rai
Publikováno v:
Kidney International Reports, Vol 3, Iss 2, Pp 356-363 (2018)
Accumulating evidence suggests that a large hospital volume (HV) is associated with favorable outcomes in various diseases or surgical procedures. The aim of this study is to clarify the correlation of HV and dialysis case volume (DCV) with in-hospit
Externí odkaz:
https://doaj.org/article/0e8615ded06b4193889512d1973cf87e
Autor:
Yuki Yoshizaki, Takayasu Mori, Mari Ishigami-Yuasa, Eriko Kikuchi, Daiei Takahashi, Moko Zeniya, Naohiro Nomura, Yutaro Mori, Yuya Araki, Fumiaki Ando, Shintaro Mandai, Yuri Kasagi, Yohei Arai, Emi Sasaki, Sayaka Yoshida, Hiroyuki Kagechika, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract The Kelch-like ECH-associating protein 1 (Keap1)-nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE) signaling pathway is the major regulator of cytoprotective responses to oxidative and electrophilic stress
Externí odkaz:
https://doaj.org/article/9033bda222a94a88a5557b6bef9e8da0
Autor:
Daiei Takahashi, Takayasu Mori, Eisei Sohara, Miyako Tanaka, Motoko Chiga, Yuichi Inoue, Naohiro Nomura, Moko Zeniya, Hiroki Ochi, Shu Takeda, Takayoshi Suganami, Tatemitsu Rai, Shinichi Uchida
Publikováno v:
EBioMedicine, Vol 18, Iss C, Pp 118-127 (2017)
The with-no-lysine kinase (WNK) 4 gene is a causative gene in pseudohypoaldosteronism type II. Although WNKs are widely expressed in the body, neither their metabolic functions nor their extrarenal role is clear. In this study, we found that WNK4 was
Externí odkaz:
https://doaj.org/article/129ae3e519444542ab2352f781a534db
Autor:
Fumiaki Ando, Eisei Sohara, Tetsuji Morimoto, Naofumi Yui, Naohiro Nomura, Eriko Kikuchi, Daiei Takahashi, Takayasu Mori, Alain Vandewalle, Tatemitsu Rai, Sei Sasaki, Yoshiaki Kondo, Shinichi Uchida
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The water channel AQP2 mediates the concentration of urine in the kidney. Here Ando et al. show that Wnt5 promotes collecting duct permeability by regulating AQP2 expression and localization through activation of the calmodulin/calcineurin signalling
Externí odkaz:
https://doaj.org/article/29e7b2aadd534db090339dd9c18e6a53
Autor:
Tse-En J. Wang, Hung-Ting Liu, Yu-Hua Lai, Tong-Rong Jan, Naohiro Nomura, Hui-Wen Chang, Chi-Chung Chou, Ya-Jane Lee, Pei-Shiue J. Tsai
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Cisplatin is a potent anti-cancer drug that has been widely used in the treatment of various cancers; however, cisplatin administration results in severe nephrotoxicity and impedes its clinical applications. In this study, we showed that honokiol, a
Externí odkaz:
https://doaj.org/article/840af774fb5440c19122c7a2ec043692
Autor:
Hiroaki Kikuchi, Eiichiro Kanda, Takayasu Mori, Hidehiko Sato, Soichiro Iimori, Naohiro Nomura, Shotaro Naito, Eisei Sohara, Tomokazu Okado, Shinichi Uchida, Kiyohide Fushimi, Tatemitsu Rai
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0208258 (2018)
In patients with chronic kidney disease (CKD), low body mass index (BMI) is associated with high mortality. This relationship in emergently hospitalized CKD patients is unknown. We investigated the association between obesity and short-term mortality
Externí odkaz:
https://doaj.org/article/3a66c332fa2f46b9b3f94f7c9c024426