Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Naohiro Mizoguchi"'
Publikováno v:
Current Research in Toxicology, Vol 7, Iss , Pp 100187- (2024)
To study the effects of drugs on embryo/fetal development (EFD), developmental and reproductive toxicity studies in zebrafish (Danio rerio) embryos is expected to be an accepted alternative method to animal studies using mammals. However, there is a
Externí odkaz:
https://doaj.org/article/66a71f0a77e84d6e8347da2a3e09741f
Autor:
Wenjing Dong, Ippo Akasaka, Akifumi Komiyama, Tatsuro Nakamura, Naohiro Mizoguchi, Tasuku Nawaji, Shinichi Ikushiro, Makoto Kobayashi, Hiroki Teraoka
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 368 (2023)
The pharmacological and toxicological effects of active metabolites of enzymes including cytochrome P450 (CYP) are important. While it has been believed for a long time that thalidomide causes characteristic limb malformation only in rabbits and prim
Externí odkaz:
https://doaj.org/article/d624408503c34d2c8c699880c61ee07c
Autor:
Tasuku Nawaji, Natsumi Yamashita, Haruka Umeda, Shuangyi Zhang, Naohiro Mizoguchi, Masanori Seki, Takio Kitazawa, Hiroki Teraoka
Publikováno v:
Pharmaceuticals, Vol 13, Iss 12, p 456 (2020)
Zebrafish are used widely in biomedical, toxicological, and developmental research, but information on their xenobiotic metabolism is limited. Here, we characterized the expression of 14 xenobiotic cytochrome P450 (CYP) subtypes in whole embryos and
Externí odkaz:
https://doaj.org/article/f21ef8a793d84d3da6bc49a9778e45eb
Autor:
Yoshinori Sato, Wenjing Dong, Tatsuro Nakamura, Naohiro Mizoguchi, Tasuku Nawaji, Miyu Nishikawa, Takenori Onaga, Shinichi Ikushiro, Makoto Kobayashi, Hiroki Teraoka
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 4013
Volume 24
Issue 4
Pages: 4013
Metabolic activation is the primary cause of chemical toxicity including hepatotoxicity. Cytochrome P450 2E (CYP2E) is involved in this process for many hepatotoxicants, including acetaminophen (APAP), one of the most common analgesics and antipyreti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116f7aefb3ed1bd08e194877a752b155
Autor:
Tasuku Nawaji1 nawaji-tasuku@ceri.jp, Naohiro Mizoguchi1, Mika Ono1, Takeshi Matuura1, Masanori Seki1, Hiroki Teraoka2
Publikováno v:
Journal of Toxicological Sciences. Aug2018, Vol. 43 Issue 4, p267-273. 7p.
Autor:
Takio Kitazawa, Natsumi Yamashita, Naohiro Mizoguchi, Haruka Umeda, Tasuku Nawaji, Hiroki Teraoka, Shuangyi Zhang, Masanori Seki
Publikováno v:
Pharmaceuticals
Pharmaceuticals, Vol 13, Iss 456, p 456 (2020)
Volume 13
Issue 12
Pharmaceuticals, Vol 13, Iss 456, p 456 (2020)
Volume 13
Issue 12
Zebrafish are used widely in biomedical, toxicological, and developmental research, but information on their xenobiotic metabolism is limited. Here, we characterized the expression of 14 xenobiotic cytochrome P450 (CYP) subtypes in whole embryos and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c890d27a82a7e34d42a83a30e8d59a01
http://europepmc.org/articles/PMC7763843
http://europepmc.org/articles/PMC7763843
Autor:
Yoko Kato-Unoki, Koki Mukai, Jae Man Lee, Tsuneyuki Tatsuke, Yohei Shimasaki, Hina Satone, Xuchun Qiu, Naohiro Mizoguchi, Mst Ruhina Margia Khanam, Takahiro Kusakabe, Ayano Teramoto, Yuji Oshima
Publikováno v:
European Journal of Phycology. 53:29-38
We investigated the gene structure and predicted amino acid sequence of the antioxidant enzyme 2-Cys peroxiredoxin (2-Cys Prx) in the raphidophyte Chattonella marina, which is a harmful algal bloom (HAB) species. The open reading frame of 2-Cys Prx w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca04e112c322e9754f0236c7f4ced1e5
https://doi.org/10.1080/09670262.2017.1346206
https://doi.org/10.1080/09670262.2017.1346206
Publikováno v:
The Journal of toxicological sciences. 43(4)
Developmental toxicity is an adverse developmental outcome, i.e., death, malformation, growth retardation, or functional deficiency. Recently, alternative methods of assessing developmental toxicity using zebrafish (Danio rerio) as a preliminary scre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d2167e38a8e1083341fcc11820e429a
https://pubmed.ncbi.nlm.nih.gov/29618715
https://pubmed.ncbi.nlm.nih.gov/29618715