Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Naohiro Kurotaki"'
Autor:
Yoshiro Morimoto, Shinji Ono, Shintaro Yoshida, Hiroyuki Mishima, Akira Kinoshita, Takeshi Tanaka, Yoshihiro Komohara, Naohiro Kurotaki, Tatsuya Kishino, Yuji Okazaki, Hiroki Ozawa, Koh-ichiro Yoshiura, Akira Imamura
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Genetic and epidemiological evidence has suggested that genetic factors are important in schizophrenia, although its pathophysiology is poorly understood. This study used whole-exome sequencing to investigate potential novel schizophrenia-ca
Externí odkaz:
https://doaj.org/article/a4ec410821e14154a3dd5e8f9b9d61a8
Autor:
Akira Nishi, Shusuke Numata, Atsushi Tajima, Xiaolei Zhu, Koki Ito, Atsushi Saito, Yusuke Kato, Makoto Kinoshita, Shinji Shimodera, Shinji Ono, Shinichiro Ochi, Akira Imamura, Naohiro Kurotaki, Shu-ichi Ueno, Nakao Iwata, Kiyoshi Fukui, Issei Imoto, Atsushi Kamiya, Tetsuro Ohmori
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Here we report de novo non-synonymous single-nucleotide variants (SNVs) by conducting whole exome sequencing of 18 trios consisting of Japanese patients with sporadic schizophrenia and their parents. Among nine SNVs, we explored the function
Externí odkaz:
https://doaj.org/article/2f03255fb4a14d7c9a0b4184ac4e7df3
Autor:
Naohiro Kurotaki, Shinya Tasaki, Hiroyuki Mishima, Shinji Ono, Akira Imamura, Taeko Kikuchi, Nao Nishida, Katsushi Tokunaga, Koh-ichiro Yoshiura, Hiroki Ozawa
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20589 (2011)
The recent development of high-resolution DNA microarrays, in which hundreds of thousands of single nucleotide polymorphisms (SNPs) are genotyped, enables the rapid identification of susceptibility genes for complex diseases. Clusters of these SNPs m
Externí odkaz:
https://doaj.org/article/9ea03aa45bba4b7fb598179c994869ad
Autor:
Takeshi Tanaka, Koh-ichiro Yoshiura, Hiroki Ozawa, Yoshiro Morimoto, Akira Kinoshita, Shinji Ono, Tatsuya Kishino, Naohiro Kurotaki, Akira Imamura, Hiroyuki Mishima, Yuji Okazaki, Shintaro Yoshida, Yoshihiro Komohara
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Translational Psychiatry
Translational Psychiatry
Genetic and epidemiological evidence has suggested that genetic factors are important in schizophrenia, although its pathophysiology is poorly understood. This study used whole-exome sequencing to investigate potential novel schizophrenia-causing gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d156a06232f0f97b3138a87eea1e24b
https://doaj.org/article/a4ec410821e14154a3dd5e8f9b9d61a8
https://doaj.org/article/a4ec410821e14154a3dd5e8f9b9d61a8
Publikováno v:
Journal of Neural Transmission
Panic disorder (PD) is a common and debilitating neuropsychiatric disorder characterized by panic attacks coupled with excessive anxiety. Both genetic factors and environmental factors play an important role in PD pathogenesis and response to treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d6046ea55d403d3023038173ff87e1
https://doi.org/10.1007/s00702-020-02205-y
https://doi.org/10.1007/s00702-020-02205-y
Publikováno v:
Pediatrics International. 64
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::901429fb29e1cc8d5dc60667fb79accc
https://doi.org/10.1111/ped.14681
https://doi.org/10.1111/ped.14681
Publikováno v:
The FASEB Journal. 34(1):180-191
Mutations of PRRT2 (proline-rich transmembrane protein 2) cause several neurological disorders, represented by paroxysmal kinesigenic dyskinesia (PKD), which is characterized by attacks of involuntary movements triggered by sudden voluntary movements
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b3d498bbdc4ea630c42ebd9f33b5af
http://hdl.handle.net/10069/39661
http://hdl.handle.net/10069/39661
Autor:
Tatsuya Kishino, Yoshihiro Komohara, Koh-ichiro Yoshiura, Naohiro Yamaguchi, Chisei Satoh, Miako Sakaguchi, Hiroyuki Mishima, Akira Imamura, Hiroki Ozawa, Masahiro Nakashima, Naohiro Kurotaki, Shintaro Yoshida, Takeshi Tanaka, Akira Kinoshita, Shinji Ono, Katsuya Matsuda, Yoshiro Morimoto
Publikováno v:
Neurology. 92:e2364-e2374
OBJECTIVE: To identify genes related to normal-pressure hydrocephalus (NPH) in one Japanese family with several members with NPH. METHODS:We performed whole-exome sequencing (WES) on a Japanese family with multiple individuals with NPH and identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6cca92d39ffc9ebd8e96f7c0398351
https://doi.org/10.1212/wnl.0000000000007505
https://doi.org/10.1212/wnl.0000000000007505
Autor:
Takahiro Tsujita, Yoshiro Morimoto, Akira Imamura, Shinji Ono, Yuji Okazaki, Hiroki Ozawa, Naohiro Kurotaki, Shinji Kanegae, Naoki Yamamoto, Hirohisa Kinoshita
Publikováno v:
Journal of Neural Transmission
Twin studies of psychiatric disorders such as schizophrenia and autism spectrum disorder have employed epidemiological approaches that determine heritability by comparing the concordance rate between monozygotic twins (MZs) and dizygotic twins. The b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1e532da04cd2d2e9bcc5e9e1133dad
https://pubmed.ncbi.nlm.nih.gov/32285255
https://pubmed.ncbi.nlm.nih.gov/32285255
Autor:
Yoshiro, Morimoto, Shintaro, Yoshida, Akira, Kinoshita, Chisei, Satoh, Hiroyuki, Mishima, Naohiro, Yamaguchi, Katsuya, Matsuda, Miako, Sakaguchi, Takeshi, Tanaka, Yoshihiro, Komohara, Akira, Imamura, Hiroki, Ozawa, Masahiro, Nakashima, Naohiro, Kurotaki, Tatsuya, Kishino, Koh-Ichiro, Yoshiura, Shinji, Ono
Publikováno v:
Neurology. 92(20)
To identify genes related to normal-pressure hydrocephalus (NPH) in one Japanese family with several members with NPH.We performed whole-exome sequencing (WES) on a Japanese family with multiple individuals with NPH and identified a candidate gene. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::454f7c190ffd3914e78194b3d2d41a06
https://pubmed.ncbi.nlm.nih.gov/31004073
https://pubmed.ncbi.nlm.nih.gov/31004073