Výsledky vyhledávání - "Naohiro Kawamoto"

Akademický článek

Calibrated ribosome profiling assesses the dynamics of ribosomal flux on transcripts

Autor: Kotaro Tomuro, Mari Mito, Hirotaka Toh, Naohiro Kawamoto, Takahito Miyake, Siu Yu A. Chow, Masao Doi, Yoshiho Ikeuchi, Yuichi Shichino, Shintaro Iwasaki

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)

Abstract Ribosome profiling, which is based on deep sequencing of ribosome footprints, has served as a powerful tool for elucidating the regulatory mechanism of protein synthesis. However, the current method has substantial issues: contamination by r

Externí odkaz: https://doaj.org/article/3e4840e33a634862b8c9b00c7dcca52c

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Akademický článek

dCas13-mediated translational repression for accurate gene silencing in mammalian cells

Autor: Antonios Apostolopoulos, Naohiro Kawamoto, Siu Yu A. Chow, Hitomi Tsuiji, Yoshiho Ikeuchi, Yuichi Shichino, Shintaro Iwasaki

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)

Abstract Current gene silencing tools based on RNA interference (RNAi) or, more recently, clustered regularly interspaced short palindromic repeats (CRISPR)‒Cas13 systems have critical drawbacks, such as off-target effects (RNAi) or collateral mRNA

Externí odkaz: https://doaj.org/article/1c2c5943edd047dbb5f597fa7b0e2f42

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Akademický článek

Damped circadian oscillation in the absence of KaiA in Synechococcus

Autor: Naohiro Kawamoto, Hiroshi Ito, Isao T. Tokuda, Hideo Iwasaki

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)

Proteins KaiA, KaiB and KaiC constitute a biochemical circadian oscillator in Synechococcus cyanobacteria. Here, Kawamoto et al. show that kaiBC promoter activity exhibits a damped, low-amplitude circadian oscillation in the absence of KaiA, which co

Externí odkaz: https://doaj.org/article/3b91fcef2e414ff9b5e9032aafbbbe34

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Na + /Ca 2+ exchanger mediates cold Ca 2+ signaling conserved for temperature-compensated circadian rhythms

Autor: Motomu Endo, Kazuhiko Kume, Naohiro Kon, Yoshitaka Fukada, Hsin Tzu Wang, Yoshiaki S. Kato, Koji Kawasaki, Hideaki Tagashira, Gen Kurosawa, Yasunori Sugiyama, Ryosuke Enoki, Tatsuto Nakane, Hideo Iwasaki, Takahiro Iwamoto, Naohiro Kawamoto, Kyouhei Uemoto

Publikováno v: Science Advances. 7

Circadian rhythms are based on biochemical oscillations generated by clock genes/proteins, which independently evolved in animals, fungi, plants, and cyanobacteria. Temperature compensation of the oscillation speed is a common feature of the circadia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864bedd9171de38c56ceee8060cdd65d
https://doi.org/10.1126/sciadv.abe8132

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Damped Oscillation in the Cyanobacterial Clock System

Autor: Naohiro Kawamoto, Yoriko Murayama, Hideo Iwasaki, Hiroshi Ito, Motohide Seki

Publikováno v: Circadian Rhythms in Bacteria and Microbiomes ISBN: 9783030721572

Although chronobiologists have postulated self-sustainability in circadian clocks, we report here two examples of damped oscillation in the cyanobacterial circadian system. First, low temperature transformed the self-sustained KaiC phosphorylation rh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cb9e74358e3f148ab0d21c63e52016c8
https://doi.org/10.1007/978-3-030-72158-9_12